Results 1 to 10 of about 290,520 (264)

Eed controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crest [PDF]

eLife
 The histone methyltransferase Polycomb repressive complex 2 (PRC2) is required for specification of the neural crest, and mis-regulation of neural crest development can cause severe congenital malformations. PRC2 is necessary for neural crest induction,
Tim Casey-Clyde, S John Liu, Angelo Pelonero, Juan Antonio Camara Serrano, Camilla Teng, Yoon-Gu Jang, Harish N Vasudevan, Arun Padmanabhan, Jeffrey Ohmann Bush, David R Raleigh   +9 more
doaj   +2 more sources

A gene regulatory network for neural induction

eLife, 2023
During early vertebrate development, signals from a special region of the embryo, the organizer, can redirect the fate of non-neural ectoderm cells to form a complete, patterned nervous system.
Katherine E Trevers, Hui-Chun Lu, Youwen Yang, Alexandre P Thiery, Anna C Strobl, Claire Anderson, Božena Pálinkášová, Nidia MM de Oliveira, Irene M de Almeida, Mohsin AF Khan, Natalia Moncaut, Nicholas M Luscombe, Leslie Dale, Andrea Streit, Claudio D Stern   +14 more
doaj   +1 more source

Depletion of Demethylase KDM6 Enhances Early Neuroectoderm Commitment of Human PSCs

Frontiers in Cell and Developmental Biology, 2021
Epigenetic modifications play a crucial role in neurogenesis, learning, and memory, but the study of their role in early neuroectoderm commitment from pluripotent inner cell mass is relatively lacking.
Yajing Meng, Tianzhe Zhang, Ran Zheng, Song Ding, Jie Yang, Ran Liu, Yingan Jiang, Wei Jiang, Wei Jiang, Wei Jiang   +9 more
doaj   +1 more source

Comparisons in temperature and photoperiodic-dependent diapause induction between domestic and wild mulberry silkworms

Scientific Reports, 2021
The bivoltine strain of the domestic silkworm, Bombyx mori, has two generations per year. It shows a facultative diapause phenotype determined by environmental conditions, including photoperiod and temperature, and nutrient conditions during embryonic ...
Takeshi Yokoyama, Shigeru Saito, Misato Shimoda, Masakazu Kobayashi, Yoko Takasu, Hideki Sezutsu, Yoshiomi Kato, Makoto Tominaga, Akira Mizoguchi, Kunihiro Shiomi   +9 more
doaj   +1 more source

I-SceI-mediated double-strand break does not increase the frequency of homologous recombination at the Dct locus in mouse embryonic stem cells. [PDF]

PLoS ONE, 2012
Targeted induction of double-strand breaks (DSBs) at natural endogenous loci was shown to increase the rate of gene replacement by homologous recombination in mouse embryonic stem cells.
Myriam Fenina, Dominique Simon-Chazottes, Sandrine Vandormael-Pournin, Jihane Soueid, Francina Langa, Michel Cohen-Tannoudji, Bruno A Bernard, Jean-Jacques Panthier   +7 more
doaj   +1 more source

Neural induction drives body axis formation during embryogenesis, but a neural induction-like process drives tumorigenesis in postnatal animals

Frontiers in Cell and Developmental Biology, 2023
Characterization of cancer cells and neural stem cells indicates that tumorigenicity and pluripotency are coupled cell properties determined by neural stemness, and tumorigenesis represents a process of progressive loss of original cell identity and gain
Ying Cao, Ying Cao, Ying Cao
doaj   +1 more source

Dnmt3bas coordinates transcriptional induction and alternative exon inclusion to promote catalytically active Dnmt3b expression

Cell Reports, 2023
Summary: Embryonic expression of DNMT3B is critical for establishing de novo DNA methylation. This study uncovers the mechanism through which the promoter-associated long non-coding RNA (lncRNA) Dnmt3bas controls the induction and alternative splicing of
Mohd Saleem Dar, Isaiah K. Mensah, Ming He, Sarah McGovern, Ikjot Singh Sohal, Hannah Christian Whitlock, Nina Elise Bippus, Madison Ceminsky, Martin L. Emerson, Hern J. Tan, Mark C. Hall, Humaira Gowher   +11 more
doaj   +1 more source

Wls is expressed in the epidermis and regulates embryonic hair follicle induction in mice. [PDF]

PLoS ONE, 2012
Wnt proteins are secreted molecules that play multiple roles during hair follicle development and postnatal hair cycling. Wntless (Wls) is a cargo protein required for the secretion of various Wnt ligands.
Sixia Huang, Xuming Zhu, Yanfang Liu, Yixin Tao, Guoyin Feng, Lin He, Xizhi Guo, Gang Ma   +7 more
doaj   +1 more source

Effect of Parental Genotypes and Their Reciprocal Crosses on Haploid Plant Production by Anther Culture and Confirmation of Double Haploids by Flow Cytometry in Bread Wheat

Journal of Agricultural Sciences, 2022
Double haploids (DHs) production and utilization is an important aspect of wheat breeding programs in worldwide, because, it provides many advantages over the conventional breeding program.
Surendra Barpete, Sancar Fatih Özcan, Güray Akdogan, Hussein Abdullah Ahmed Ahmed   +3 more
doaj   +1 more source

Caspase dependent programmed cell death in developing embryos: a potential target for therapeutic intervention against pathogenic nematodes. [PDF]

PLoS Neglected Tropical Diseases, 2011
BACKGROUND: Successful embryogenesis is a critical rate limiting step for the survival and transmission of parasitic worms as well as pathology mediated by them.
Alok Das Mohapatra, Sunil Kumar, Ashok Kumar Satapathy, Balachandran Ravindran   +3 more
doaj   +1 more source