Results 11 to 20 of about 290,520 (264)

Sensitive windows for within- and trans-generational plasticity of anti-predator defences

Peer Community Journal, 2023
Transgenerational plasticity could be an important mechanism for adaptation to variable environments in addition to within-generational plasticity. But its potential for adaptation may be restricted to specific developmental windows that are highly ...
Tariel-Adam, Juliette, Luquet, Émilien, Plénet, Sandrine   +2 more
doaj   +1 more source

Efficient definitive endoderm induction from mouse embryonic stem cell adherent cultures: A rapid screening model for differentiation studies

Stem Cell Research, 2014
Definitive endoderm (DE) differentiation from mouse embryonic stem cell (mESC) monolayer cultures has been limited by poor cell survival or low efficiency.
Josué Kunjom Mfopou, Marloes Geeraerts, Roba Dejene, Stijn Van Langenhoven, Asma Aberkane, Leo A. Van Grunsven, Luc Bouwens   +6 more
doaj   +1 more source

Exosomes as secondary inductive signals involved in kidney organogenesis

Journal of Extracellular Vesicles, 2018
The subfraction of extracellular vesicles, called exosomes, transfers biological molecular information not only between cells but also between tissues and organs as nanolevel signals.
Mirja Krause, Aleksandra Rak-Raszewska, Florence Naillat, Ulla Saarela, Christina Schmidt, Veli-Pekka Ronkainen, Geneviève Bart, Seppo Ylä-Herttuala, Seppo J. Vainio   +8 more
doaj   +1 more source

Differentiation of Mouse Embryonic Stem Cells to Neuronal Cells Using Hanging Droplets and Retinoic Acid

Bio-Protocol, 2019
Controlled differentiation of embryonic stem cells is an essential tool in stem cell research. In this protocol, we describe a simple differentiation protocol involving the induction of embryoid body formation in mouse embryonic stem cells (mESC) using ...
Jeroen Witteveldt, Sara Macias
doaj   +1 more source

Self-contained induction of neurons from human embryonic stem cells. [PDF]

PLoS ONE, 2009
BACKGROUND: Neurons and glial cells can be efficiently induced from mouse embryonic stem (ES) cells in a conditioned medium collected from rat primary-cultured astrocytes (P-ACM).
Tsuyoshi Okuno, Takashi Nakayama, Nae Konishi, Hideo Michibata, Koji Wakimoto, Yutaka Suzuki, Shinji Nito, Toshio Inaba, Imaharu Nakano, Shin-Ichi Muramatsu, Makoto Takano, Yasushi Kondo, Nobuo Inoue   +12 more
doaj   +1 more source

OCT4B2, a novel alternative spliced variant of OCT4, is significantly upregulated under heat-stress condition and downregulated in differentiated cells

Tumor Biology, 2017
OCT4 is a crucial transcription factor that maintains self-renewal and pluripotency of embryonic stem and embryonic carcinoma cells. The human OCT4 gene can generate at least three variants (OCT4A, OCT4B, and OCTB1) via alternative splicing and ...
Ensieh M Poursani, Majid Mehravar, Bahram Mohammad Soltani, Seyed Javad Mowla   +3 more
doaj   +1 more source

Gene regulatory network interactions in sea urchin endomesoderm induction. [PDF]

PLoS Biology, 2009
A major goal of contemporary studies of embryonic development is to understand large sets of regulatory changes that accompany the phenomenon of embryonic induction. The highly resolved sea urchin pregastrular endomesoderm-gene regulatory network (EM-GRN)
Aditya J Sethi, Robert C Angerer, Lynne M Angerer   +2 more
doaj   +1 more source

Establishment of an Embryonic Tip Regeneration System of Soybean

Brazilian Archives of Biology and Technology
In order to establish an optimal soybean embryonic tip regeneration system that can serve as soybean genetic transformation receptor, and be used for the study of genetic function verification, the influences of single factor on the adventitious bud of ...
LIU Si-yan, LI Guang-long, QU Jing, GUAN Shu-yan, YAO Dan, WANG Pi-wu, LIU Si-chen, JIA Yang, GUAN Peng-fei, WANG Long-qing   +9 more
doaj   +1 more source

Generation of human pluripotent stem cell lines with suppressed expression of the Notch ligand DLL4 using short hairpin RNAs

Stem Cell Research, 2016
Studies with different animal models have shown that the Notch ligand DLL4 has a key role in the development of the embryonic vasculature. Here we describe the generation and characterization of a human embryonic stem cell line and an induced pluripotent
Federico González-Pozas, Rosa Montes, Lourdes López-Onieva, Tamara Romero, Joan Domingo-Reinés, Pedro J. Real, Verónica Ramos-Mejía, Verónica Ayllón   +7 more
doaj   +1 more source

Experiments on Embryonic Induction [PDF]

Journal of Experimental Biology, 1934
ABSTRACT It is shown that the ectoderm of the area opaca of chick embryos of the primitive streak stage can react to primitive streak grafts by the formation of an induced neural plate. The conclusion is drawn that the competence to form neural plate is not conferred on ectoderm by the gut endoderm, which determines the formation of the ...
openaire   +2 more sources