Results 201 to 210 of about 1,293,017 (382)

Complete Meiosis from Embryonic Stem Cell-Derived Germ Cells In Vitro.

Cell Stem Cell, 2016
Quan Zhou, Mei Wang, Yan Yuan, Xuepeng Wang, Rui Fu, Haifeng Wan, Mingming Xie, Mingxi Liu, Xuejiang Guo, Ying Zheng, Guihai Feng, Qinghua Shi, Xiao-Yang Zhao, J. Sha, Qi Zhou   +14 more
semanticscholar   +1 more source

ZNHIT3 Regulates Translation to Ensure Cell Lineage Differentiation in Mouse Preimplantation Development

Advanced Science, EarlyView.
Box C/D snoRNP complex regulates protein translation. This study identifies ZNHIT3 as a key component of the complex and ensures normal protein expression, including transcription factors orchestrating cell fate commitment, during early mouse embryogenesis.
Guanghui Yang, Qiliang Xin, Jurrien Dean
wiley   +1 more source

Expression of AML1-d, a short human AML1 isoform, in embryonic stem cells suppresses in vivo tumor growth and differentiation [PDF]

, 1998
Revital Ben Aziz‐Aloya, Ditsa Levanon, Heather A. Karn, Debora Kidron, Dalia Goldenberg, Joseph Lotem, Sylvie Polak-Chaklon, Yoram Groner   +7 more
openalex   +1 more source

Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome

Nature Genetics, 2015
S. Schoenfelder, R. Sugar, Andrew Dimond, B. Javierre, Harry Armstrong, Borbála Mifsud, Emilia Dimitrova, Louise S. Matheson, Filipe Tavares-Cadete, M. Furlan-Magaril, A. Segonds-Pichon, W. Jurkowski, S. Wingett, Kristina Tabbada, Simon Andrews, Bram Herman, E. Leproust, Cameron S. Osborne, H. Koseki, P. Fraser, N. Luscombe, Sarah Elderkin   +21 more
semanticscholar   +1 more source

3D‐Printed Biomimetic Vascular Scaffold Crosslinked with Heparan Sulfate for Sustained Release of PDGFB‐LG4 Fusion Protein Promotes Bone Regeneration

Advanced Science, EarlyView.
Fusion protein PDGFB‐LG4 exhibits superior osteoinductive and angiogenic activity compared to PDGFB. The PCLHS‐PDGFB‐LG4 scaffold, featuring perfusable and permeable vascular‐like networks, promotes angiogenesis and osteogenesis through the sustained release of PDGFB‐LG4, thereby accelerating the bone defect repair process.
Jiahua Duan, Gaofei Qian, Huikang Zhang, Feifan Wang, Qiang Tian, Dong Lei, Jianning Zhao   +6 more
wiley   +1 more source

First-in-human clinical study of an embryonic stem cell product for urea cycle disorders. [PDF]

Stem Cell Res Ther
Umezawa A, Fukuda A, Horikawa R, Uchida H, Enosawa S, Oishi Y, Nakamura N, Sasaki K, Yanagi Y, Shimizu S, Nakao T, Kodama T, Sakamoto S, Hayakawa I, Akiyama S, Saku N, Miyata S, Ite K, Javaregowda PK, Toyoda M, Nonaka H, Nakamura K, Ito Y, Fukuhara Y, Miyazaki O, Nosaka S, Nakabayashi K, Haga C, Yoshioka T, Masuda A, Ohkura T, Yamazaki-Inoue M, Machida M, Abutani-Sakamoto R, Miyajima S, Akutsu H, Matsubara Y, Igarashi T, Kasahara M.   +38 more
europepmc   +1 more source

Gene conversion during vector insertion in embryonic stem cells [PDF]

, 1995
Paul Hasty, Jaime A. Rivera‐Pérez, Allan Bradley   +2 more
openalex   +1 more source

MRAS: Master Regulator Analysis of Alternative Splicing

Advanced Science, EarlyView.
This study developed a computational approach called MRAS, designed to identify master regulators of splicing differences across various biological contexts. In this framework, altered RBP expression, rather than spliceosomal mutations or other modifications, plays a central role in driving these splicing differences.
Lei Zhou, Yue Huang, Yang Zhao, Dan Guo, Xiao Wen, Ruihong Xu, Xuan Lv, Song Wu, Sicheng Jing, Zhaoqi Liu   +9 more
wiley   +1 more source

Saponins enhance the stability and cost-efficiency of human embryonic stem cell culture. [PDF]

Cell Regen
Shi J, Wu M, Fang S, Liu Z, Liu H, Zhao Y, Liu L, Shao Z.   +7 more
europepmc   +1 more source

Testing an “In-Out” Targeting Procedure for Making Subtle Genomic Modifications in Mouse Embryonic Stem Cells

, 1991
Vicky Valancius, Oliver Smithies
openalex   +2 more sources