Results 41 to 50 of about 1,324,654 (403)
Differential elasticity in lineage segregation of embryonic stem cells [PDF]
arXiv, 2022 The question of what guides lineage segregation is central to development, where cellular differentiation leads to segregated cell populations destined for specialized functions. Here, using optical tweezers measurements of mouse embryonic stem cells (mESCs), we reveal a mechanical mechanism based on differential elasticity in the second lineage ...
arxiv
Dynamics of single human embryonic stem cells and their pairs: a quantitative analysis [PDF]
Scientific Reports 7, 570 (2017), 2016 Numerous biological approaches are available to characterise the mechanisms which govern the formation of human embryonic stem cell (hESC) colonies. To understand how the kinematics of single and pairs of hESCs impact colony formation, we study their mobility characteristics using time-lapse imaging.
arxiv +1 more source
Democracy Derived? New Trajectories in Pluripotent Stem Cell Research [PDF]
, 2011 How has the development of human induced pluripotent stem cells (hiPSCs) modified the trajectory of stem cell research? Here, coauthorship networks of stem cell research articles and analysis of cell lines used in stem cell research indicate that hiPSCs ...
DeRouen, Mindy C. +3 more
core +1 more source
Tracking the embryonic stem cell transition from ground state pluripotency
Development, 2016 Mouse embryonic stem (ES) cells are locked into self-renewal by shielding from inductive cues. Release from this ground state in minimal conditions offers a system for delineating developmental progression from naïve pluripotency.
Tüzer Kalkan +13 more
semanticscholar +1 more source
Stem cells in the embryonic kidney [PDF]
Kidney International, 2008 The mammalian kidney, the metanephros, is formed by a reciprocally inductive interaction between two precursor tissues, the metanephric mesenchyme and the ureteric bud. The ureteric bud induces the metanephric mesenchyme to differentiate into the epithelia of glomeruli and renal tubules.
openaire +3 more sources
Journal of Immunology Research, 2020 Epidemiological studies have demonstrated that interleukin-10 (IL-10) polymorphisms may be associated with the development of Behcet’s disease (BD). However, the published results were inconsistent. Therefore, this meta-analysis was conducted to derive a
Xue-Feng Li +4 more
doaj +1 more source
Cell Death and Disease, 2022 Deregulated lncRNAs play critical roles in tumorigenesis and tumor progression. NR2F1-AS1 is an antisense lncRNA of NR2F1. However, the biological function of NR2F1-AS1 in gastric cancer (GC) remains largely unclear. In this study, we revealed that NR2F1-
Dandan Li +9 more
doaj +1 more source
The King is Dead, Long Live the King: Entering A New Era of Stem Cell Research and Clinical Development [PDF]
, 2011 In mid November the biopharma industry was shocked by the announcement from Geron that they were ending work on embryonic stem cell research and therapy.
Ichim, Thomas +2 more
core +3 more sources
Journal of Translational Medicine, 2023 Background Clinically, Charcot-Marie-Tooth disease (CMT)-associated muscle atrophy still lacks effective treatment. Deletion and mutation of L-periaxin can be involved in CMT type 4F (CMT4F) by destroying the myelin sheath form, which may be related to ...
Ruo-nan Zhang +21 more
doaj +1 more source
Hypoxia Signaling Pathway in Stem Cell Regulation: Good and Evil [PDF]
, 2018 Purpose of Review: This review summarizes the role of hypoxia and hypoxia-inducible factors (HIFs) in the regulation of stem cell biology, specifically focusing on maintenance, differentiation, and stress responses in the context of several stem cell ...
Aljoufi, Arafat +3 more
core +1 more source