Human stem cells and articular cartilage regeneration. [PDF]
, 2012 The regeneration of articular cartilage damaged due to trauma and posttraumatic osteoarthritis is an unmet medical need. Current approaches to regeneration and tissue engineering of articular cartilage include the use of chondrocytes, stem cells ...
Inui, Atsuyuki +2 more
core +4 more sources
Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals
Advanced Functional Materials, EarlyView.This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee +4 more
wiley +1 more source
Toward an animal model of cystic fibrosis: targeted interruption of exon 10 of the cystic fibrosis transmembrane regulator gene in embryonic stem cells. [PDF]
, 1991 Beverly H. Koller +7 more
openalex +3 more sources
Dissection of Autophagosome Formation Using Apg5-Deficient Mouse Embryonic Stem Cells
Journal of Cell Biology, 2001 In macroautophagy, cytoplasmic components are delivered to lysosomes for degradation via autophagosomes that are formed by closure of cup-shaped isolation membranes. However, how the isolation membranes are formed is poorly understood.
N. Mizushima +8 more
semanticscholar +1 more source
Germ-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cells. [PDF]
, 1989 Beverly H. Koller +8 more
openalex +1 more source
Embryonic Stem Cells: Introducing Exogenous Regulators into Embryonic Stem Cells [PDF]
, 2011 The application of embryonic stem (ES) cells to research and therapy has been a landmark development in science. Cell therapy using ES cells depends on the progress of the stable culture conditions and differentiation induction methods. ES cells were first obtained directly from inner cell masses (ICMs) of blastocysts by Evans and Kaufman (1981), and ...
openaire +3 more sources
Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis
Advanced Healthcare Materials, EarlyView.This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han +7 more
wiley +1 more source
Cells, 2019 A population of small stem cells with diameters of up to 5 μm resembling very small embryonic-like stem cells (VSELs) were sorted from human embryonic stem cell (hESC) cultures using magnetic-activated cell sorting (MACS) based on the expression of ...
Irma Virant-Klun +4 more
doaj +1 more source
Why not "do simple things in a simple way": Use of the Pap test as the first step in screening genetic stability for human cultured stem cell therapy? [PDF]
, 2011 The aim of this study was to analyze adipose tissue-derived mesenchymal stem cells (AT-MSCs) using the Pap test as a first screening step to evaluate genetic stability.
Ana Carolina Irioda +13 more
core +1 more source
Microgravity Reduces the Differentiation and Regenerative Potential of Embryonic Stem Cells
Stem Cells and Development, 2015 Mechanical unloading in microgravity is thought to induce tissue degeneration by various mechanisms, including inhibition of regenerative stem cell differentiation.
E. Blaber +7 more
semanticscholar +1 more source