Results 171 to 180 of about 354,563 (218)
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The Validated Embryonic Stem Cell Test with Murine Embryonic Stem Cells
2018Birth defects are the leading cause of infant mortality in the USA, yet the causes of most of these conditions are unknown. While a combination of genetic and environmental factors are suspected in most cases, little information exists about the health risks that prenatal exposure to many common chemicals poses for the fetus.
Lauren M, Walker +2 more
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Journal of Cell Science, 2000
ABSTRACT Embryonic stem (ES) cells are cells derived from the early embryo that can be propagated indefinitely in the primitive undifferentiated state while remaining pluripotent; they share these properties with embryonic germ (EG) cells. Candidate ES and EG cell lines from the human blastocyst and embryonic gonad can differentiate into
M F, Pera, B, Reubinoff, A, Trounson
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ABSTRACT Embryonic stem (ES) cells are cells derived from the early embryo that can be propagated indefinitely in the primitive undifferentiated state while remaining pluripotent; they share these properties with embryonic germ (EG) cells. Candidate ES and EG cell lines from the human blastocyst and embryonic gonad can differentiate into
M F, Pera, B, Reubinoff, A, Trounson
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Embryonic Stem Cells and Infertility
American Journal of Perinatology, 2018AbstractEmbryonic stem cells (ESCs) have the ability to differentiate into several cell lineages and self-renew. Through a spontaneous process, ESCs can differentiate into germ cells of various stages, partly due to their self-renewal ability and their microenvironment culture.
Nahid, Lorzadeh, Nastaran, Kazemirad
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2006
Bovine embryonic stem (bES) cell lines reported to date vary in morphology and marker expression, such as alkaline phosphatase (ALPL), stage-specific embryonic antigen 4 (SSEA4), and octamer-binding transcription factor-4 (OCT4), that normally are associated with the undifferentiated, pluripotent state.
Marsha, Roach +3 more
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Bovine embryonic stem (bES) cell lines reported to date vary in morphology and marker expression, such as alkaline phosphatase (ALPL), stage-specific embryonic antigen 4 (SSEA4), and octamer-binding transcription factor-4 (OCT4), that normally are associated with the undifferentiated, pluripotent state.
Marsha, Roach +3 more
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Pluripotency of embryonic stem cells
Cell and Tissue Research, 2007Embryonic stem (ES) cells derived from pre-implantation embryos have the potential to differentiate into any cell type derived from the three germ layers of ectoderm (epidermal tissues and nerves), mesoderm (muscle, bone, blood), and endoderm (liver, pancreas, gastrointestinal tract, lungs), including fetal and adult cells.
Yamanaka, S +7 more
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Neurosurgery Clinics of North America, 2007
Human embryonic stem cells (hESCs) are stable in terms of their pluripotency, karyotype, global gene expression, ability to repair DNA and maintain telomerase levels, and growth characteristics. hESCs offer a renewable source of a wide range of cell types for use in research and cell-based therapies to treat disease.
Cleo, Choong, Mahendra S, Rao
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Human embryonic stem cells (hESCs) are stable in terms of their pluripotency, karyotype, global gene expression, ability to repair DNA and maintain telomerase levels, and growth characteristics. hESCs offer a renewable source of a wide range of cell types for use in research and cell-based therapies to treat disease.
Cleo, Choong, Mahendra S, Rao
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Differentiation of Embryonic Stem Cells
Current Protocols in Neuroscience, 1997AbstractEmbryonic stem (ES) cells are pluripotent cells whose developmental state is equivalent to cells of the inner cell mass in the blastocyst‐stage embryo. This unit presents a method of producing differentiated ES cells in which the cells are first aggregated on a less adhesive surface to form embryoid bodies (EBs).
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2012
The embryonic stem cell test is an animal-free alternative test method for developmental toxicity. Mouse embryonic stem cells are cultured in a hanging drop method to form embryoid bodies. These embryoid bodies, when plated on tissue culture dishes, differentiate to form contracting myocardial cell foci within 10 days.
Sjors H W, Schulpen, Aldert H, Piersma
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The embryonic stem cell test is an animal-free alternative test method for developmental toxicity. Mouse embryonic stem cells are cultured in a hanging drop method to form embryoid bodies. These embryoid bodies, when plated on tissue culture dishes, differentiate to form contracting myocardial cell foci within 10 days.
Sjors H W, Schulpen, Aldert H, Piersma
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EMBRYONIC POTENTIAL AND STEM CELLS
Bioethics, 2007ABSTRACTThis paper examines three arguments that use the concept of potential to identify embryos that are morally suitable for embryonic stem cell research (ESCR). According to the first argument, due to Ronald Green, the fact that they are scheduled for disposal makes embryos left over from IVF treatments morally appropriate for research. Paul McHugh
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Mutation in Embryonic Stem Cells
Science, 2001A single human embryonic stem (es) cell might be modified in the laboratory to provide an unlimited supply of cells for therapy, according to Geron researcher Melissa Carpenter in the News Focus article “Stem cells: new excitement, persistent questions” (G. Vogel, 1 Dec., p.
L, Roccanova, P, Ramphal, P, Rappa
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