Results 201 to 210 of about 5,338,715 (307)

Correction: CXCL13 suppresses liver regeneration through the negative regulation of HGF signaling

Cell Death and Disease
Qun Zhao, Jingyi Wu, Mengyuan Feng, Anjie Zhang, Liwei Fu, Jinglin Chen, Lian Li, Fangzhou Li, Tingting Li, Shu Jin, Shengbao Li, Xianjun Yu   +11 more
doaj   +1 more source

Transcriptome profiling of ocular surface ectoderm derived from embryonic stem cells, and identification of CACNG6 and AQP3 as its surface markers. [PDF]

Int J Ophthalmol
Sun L, Li YM, Song YW, Yang YC, Duan L, Gao Y, Li JX, Yu YK, Pang KP, Dang GF, Zhang CW.   +10 more
europepmc   +1 more source

SDF‐1 Attenuates Oocyte Quality Decline During Reproductive Aging Through Autophagy‐Enhanced Stress Granule Scavenging

Advanced Science, EarlyView.
SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long, Meng Wang, Ruolin Mao, Hong Chen, Juepu Zhou, Xiangfei Wang, Zheng Yuan, Ri‐Cheng Chian, Nan Xiao, Qingsong Xi, Yimin Shu, Lei Jin, Lixia Zhu   +12 more
wiley   +1 more source

EpCAM supports exit from pluripotency of embryonic stem cells via Eomes. [PDF]

Cell Death Dis
Gong N, Gouda M, Balaz AM, Song J, Kranz G, Hess J, Baumeister P, Unger K, Katalina V, Canis M, Gires O.   +10 more
europepmc   +1 more source

Tumor‐Derived Exosomal circAP2B1 Induces M2 Macrophage Polarization by Enhancing Mitochondrial Homeostasis to Promote Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
ESCC‐derived exosomal circAP2B1 promotes tumor progression by reprogramming mitochondrial metabolism via the ESRRA/KPNA1/MFN2 axis to induce M2 polarization of macrophages. ABSTRACT Esophageal squamous cell carcinoma (ESCC) remodels the immunosuppressive tumor microenvironment via exosome‐mediated intercellular communication.
Yiru Wang, Gang Feng, Youyu Wang, Ruihao Liang, Haixia Pan, Kai Lei   +5 more
wiley   +1 more source

Naïve pluripotency and genomic stability are coordinated in embryonic stem cells by a novel pluripotency regulator ZFP998. [PDF]

Nucleic Acids Res
Tang M, Wang L, Liu JW, Zhong WH, Wu H, Nie WH, Li GM, Zhang WD, Zhou H, Gao J, Zheng P.   +10 more
europepmc   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Early replication fragile sites are associated with cancer-related CNVs and SNVs in human embryonic stem cells. [PDF]

Stem Cell Reports
Dong YP, Qiu M, Tang H, Shi W, Lu Y, Ji F, Liao H, Ying S, Zheng P, Wang L.   +9 more
europepmc   +1 more source

Long Noncoding RNA PCALRx Interacts with Pyruvate Carboxylase to Drive Multi‐Organ Developmental Toxicity in Zebrafish Embryos Exposed to Amoxicillin

Advanced Science, EarlyView.
Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao, Ping Jiang, Xinli Zhou, Mengying Yin, Qiong Luo, Hui Wang   +5 more
wiley   +1 more source

Deletion of activating transcription factor 3 (Atf3) promotes cardiomyocyte differentiation from embryonic stem cells. [PDF]

Sci Rep
Su L, Jiang Z, He R, Wu M, Shu Y, Liu Z, Li C, Liu S.   +7 more
europepmc   +1 more source