Results 261 to 270 of about 565,140 (354)

Stub1 maintains proteostasis of master transcription factors in embryonic stem cells

Md Mahfuz Al Mamun, Muhammad Riaz Khan, Yifu Zhu, Yuwei Zhang, Shuai Zhou, Ran Xu, Ihtisham Bukhari, Rick F. Thorne, Jinming Li, Xu Dong Zhang, Guangzhi Liu, Song Chen, Mian Wu, Xiaoyuan Song   +13 more
openalex   +1 more source

Nanoscale Mapping of the Subcellular Glycosylation Landscape

Advanced Science, EarlyView.
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter, Steffen Sass, Mike Heilemann, Thomas Kuner, Maja Klevanski   +4 more
wiley   +1 more source

BACH1 recruits STAT3 to enhance leukemia inhibitory factor receptor activity and augments the self-renewal capacity of mouse embryonic stem cells. [PDF]

Stem Cell Res Ther
Ma J, Ma S, Niu C, Wang S, Wei X, Meng D, Zhi X, Guo J.   +7 more
europepmc   +1 more source

A Novel SALL4/OCT4 Transcriptional Feedback Network for Pluripotency of Embryonic Stem Cells

, 2010
Jianchang Yang, Chong Gao, Li Chai, Yupo Ma   +3 more
openalex   +2 more sources

Mechanical Environment Afforded by Engineered Hydrogel Critically Regulates Survival of Neural Stem Cells Transplanted in the Injured Spinal Cord via Piezo1‐Mediated Mechanotransduction

Advanced Science, EarlyView.
Neural stem cell transplantation shows promise for spinal cord repair, but poor graft survival limits therapeutic efficacy. This study demonstrates that increasing hydrogel stiffness from 10% to 16% concentration significantly enhances transplanted neural stem cell survival through Piezo1‐mediated mechanotransduction, revealing mechanical properties as
Hee Hwan Park, Yurim Kim, Byeong Seong Jang, Simay Genişcan, Dong Hoon Hwang, Yeojin Seo, Seung‐Ah Jee, Hyo Gyeong Seo, Hyung Soon Kim, Ariandokht Einisadr, Ho‐Jeong Kim, Seolhee Lee, Sangwoo Kwon, Kyung Sook Kim, Kang In Lee, Jae Young Lee, Joo Min Park, Young‐Min Kim, Soo‐Chang Song, Byung Gon Kim   +19 more
wiley   +1 more source

Discovery of NANOG enhancers and their essential roles in self-renewal and differentiation in human embryonic stem cells. [PDF]

Stem Cell Reports
Yan J, Luo R, Rosen BP, Liu D, Wong W, Leslie CS, Huangfu D.   +6 more
europepmc   +1 more source

YKT6 Promotes Bladder Cancer Progression by Stabilizing β‐catenin Through USP7‐Mediated Deubiquitination

Advanced Science, EarlyView.
The SNARE protein YKT6 is upregulated in bladder cancer (BLCA), correlating with poor prognosis. YKT6 promotes tumor proliferation and metastasis by activating Wnt/β‐catenin signaling. It recruits Ubiquitin‐Specific Peptidase 7 (USP7) to deubiquitinate and stabilize β‐catenin, enhancing its nuclear accumulation and driving oncogenic gene expression ...
Sheng Tu, Wenzhi Du, Yongwen Luo, Jiageng Shi, Tianyun Liu, Meng Ji, Kangping Xiong, Siming Chen, Fenfang Zhou, Mingxing Li, Jingtian Yu, Gang Wang, Lingao Ju, Yi Zhang, Yu Xiao, Xinghuan Wang, Kaiyu Qian   +16 more
wiley   +1 more source

Domain-specific AI segmentation of IMPDH2 rod/ring structures in mouse embryonic stem cells. [PDF]

BMC Biol
Ball STM, Hennessy MJ, Tan Y, Hoettges KF, Perkins ND, Wilkinson DJ, White MRH, Zheng Y, Turner DA.   +8 more
europepmc   +1 more source

Inhibition of TGFß signaling supports embryonic stem cell derivation and the ground state of pluripotency in mouse

, 2014
Sabitri Ghimire, Björn Heindryckx, Jitesh Neupane, Dieter Deforce, Tom Deroo, Petra De Sutter   +5 more
openalex   +1 more source

Analysis of altered gene expression specific to embryotoxic chemical treatment during embryonic stem cell differentiation into myocardiac and neural cells

, 2011
Noriyuki Suzuki, Satoshi Ando, Kayo Sumida, Nobuyuki Horie, Koichi Saito   +4 more
openalex   +2 more sources