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Stem Cells and Development, 2007
Stem cells are unique cell populations with the ability to choose between self-renewal and differentiation. Embryonic stem (ES) cells have the ability to form any fully differentiated cell of the body. To date, only three species of mammals have yielded long-term cultures of self-renewing ES cells- mice, monkeys, and humans.
Atindriya, Biswas, Robert, Hutchins
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Stem cells are unique cell populations with the ability to choose between self-renewal and differentiation. Embryonic stem (ES) cells have the ability to form any fully differentiated cell of the body. To date, only three species of mammals have yielded long-term cultures of self-renewing ES cells- mice, monkeys, and humans.
Atindriya, Biswas, Robert, Hutchins
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Neurosurgery Clinics of North America, 2007
Human embryonic stem cells (hESCs) are stable in terms of their pluripotency, karyotype, global gene expression, ability to repair DNA and maintain telomerase levels, and growth characteristics. hESCs offer a renewable source of a wide range of cell types for use in research and cell-based therapies to treat disease.
Cleo, Choong, Mahendra S, Rao
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Human embryonic stem cells (hESCs) are stable in terms of their pluripotency, karyotype, global gene expression, ability to repair DNA and maintain telomerase levels, and growth characteristics. hESCs offer a renewable source of a wide range of cell types for use in research and cell-based therapies to treat disease.
Cleo, Choong, Mahendra S, Rao
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2014
Embriyonik kök hücre, embriyoda erken evrede bulunan totipotent kök hücreler olarak tanımlanırlar. Embriyonik kök hücreler, erken embriyonik dönemde inner cell mass (ICM) kısmından elde edilir ve in vitro olarak bütün somatik hücrelere dönüşebilme yeteneği vardır.
Irina Klimanskaya +2 more
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Embriyonik kök hücre, embriyoda erken evrede bulunan totipotent kök hücreler olarak tanımlanırlar. Embriyonik kök hücreler, erken embriyonik dönemde inner cell mass (ICM) kısmından elde edilir ve in vitro olarak bütün somatik hücrelere dönüşebilme yeteneği vardır.
Irina Klimanskaya +2 more
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Journal of Cell Science, 2000
ABSTRACT Embryonic stem (ES) cells are cells derived from the early embryo that can be propagated indefinitely in the primitive undifferentiated state while remaining pluripotent; they share these properties with embryonic germ (EG) cells. Candidate ES and EG cell lines from the human blastocyst and embryonic gonad can differentiate into
M F, Pera, B, Reubinoff, A, Trounson
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ABSTRACT Embryonic stem (ES) cells are cells derived from the early embryo that can be propagated indefinitely in the primitive undifferentiated state while remaining pluripotent; they share these properties with embryonic germ (EG) cells. Candidate ES and EG cell lines from the human blastocyst and embryonic gonad can differentiate into
M F, Pera, B, Reubinoff, A, Trounson
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Best Practice & Research Clinical Obstetrics & Gynaecology, 2016
The establishment of permanent human embryonic stem cell lines (hESCs) was first reported in 1998. Due to their pluripotent nature and ability to differentiate to all cell types in the body, they have been considered as a cell source for regenerative medicine. Since then, intensive studies have been carried out regarding factors regulating pluripotency
Pauliina, Damdimopoulou +5 more
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The establishment of permanent human embryonic stem cell lines (hESCs) was first reported in 1998. Due to their pluripotent nature and ability to differentiate to all cell types in the body, they have been considered as a cell source for regenerative medicine. Since then, intensive studies have been carried out regarding factors regulating pluripotency
Pauliina, Damdimopoulou +5 more
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Trends in Cell Biology, 2012
Embryonic stem cells (ESCs) - undifferentiated cells originating from preimplantation stage embryos - have prolonged self-renewal capacity and are pluripotent. Activation of the canonical Wnt pathway is implicated in maintenance of and exit from the pluripotent state. Recent findings demonstrate that the essential mediator of canonical Wnt signaling, β-
Jason, Wray, Christine, Hartmann
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Embryonic stem cells (ESCs) - undifferentiated cells originating from preimplantation stage embryos - have prolonged self-renewal capacity and are pluripotent. Activation of the canonical Wnt pathway is implicated in maintenance of and exit from the pluripotent state. Recent findings demonstrate that the essential mediator of canonical Wnt signaling, β-
Jason, Wray, Christine, Hartmann
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2006
Bovine embryonic stem (bES) cell lines reported to date vary in morphology and marker expression, such as alkaline phosphatase (ALPL), stage-specific embryonic antigen 4 (SSEA4), and octamer-binding transcription factor-4 (OCT4), that normally are associated with the undifferentiated, pluripotent state.
Marsha, Roach +3 more
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Bovine embryonic stem (bES) cell lines reported to date vary in morphology and marker expression, such as alkaline phosphatase (ALPL), stage-specific embryonic antigen 4 (SSEA4), and octamer-binding transcription factor-4 (OCT4), that normally are associated with the undifferentiated, pluripotent state.
Marsha, Roach +3 more
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Advances in Pediatrics, 2008
ES cell research represents an exploding field of exploration. Initially predicted to provide rapid cures for numerous human diseases, the clinical usefulness of ES cell-derived cells remains untested in humans. However, ES cells have rapidly expanded our knowledge of human development and the molecular details of differentiation.
Michael K, Fritsch, Don B, Singer
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ES cell research represents an exploding field of exploration. Initially predicted to provide rapid cures for numerous human diseases, the clinical usefulness of ES cell-derived cells remains untested in humans. However, ES cells have rapidly expanded our knowledge of human development and the molecular details of differentiation.
Michael K, Fritsch, Don B, Singer
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2006
Embryonic stem (ES) cells are derived from preimplantation stage mouse embryos at the time when they have reached the blastocyst stage. It is at this point that the first steps of differentiation take place during mammalian embryonic development.
Andras, Nagy, Kristina, Vintersten
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Embryonic stem (ES) cells are derived from preimplantation stage mouse embryos at the time when they have reached the blastocyst stage. It is at this point that the first steps of differentiation take place during mammalian embryonic development.
Andras, Nagy, Kristina, Vintersten
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