Results 101 to 110 of about 3,399,190 (337)

“Noninvasive predictive marker for esophageal variceal bleeding”

open access: yesBMC Gastroenterology
Objective Esophageal varices are common in cirrhosis with portal hypertension; some patients face high risk of life-threatening esophageal variceal bleeding (EVB).
Shuo Zhang   +3 more
doaj   +1 more source

Tick exposure biomarkers: A One Health approach to new tick surveillance tools

open access: yesCurrent Research in Parasitology and Vector-Borne Diseases
The spread of tick-borne disease (TBD) is escalating globally, driven by climate change and socio-economic shifts, underlining the urgency to improve surveillance, diagnostics, and control strategies.
Alexis Dziedziech   +4 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Update on tick-borne pathogens detection methods within ticks

open access: yesCurrent Research in Parasitology and Vector-Borne Diseases
Ticks are known vectors of various pathogens, including bacteria, parasites and viruses, that impact both animal and human health. Improving knowledge of the distribution of tick-borne pathogens, combined with their early detection in ticks, are ...
Eva Krupa   +3 more
doaj   +1 more source

ACUTE ARTICULAR SYNDROME. THE CONCEPT OF EMERGENCY CARE IN RHEUMATOLOGY

open access: yesНаучно-практическая ревматология, 2018
The absence of a current emergency care system for rheumatic patients makes the solution of this problem relevant. Objective: to create and test a health care system for patients with acute articular syndrome (AAS) and to analyze the distribution of ...
A. S. Povzun, V. I. Mazurov
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Developing a conceptual model for exploring emergence [PDF]

open access: yes, 2006
Emergence is a fundamental property of complex systems and can be thought of as a new property or behaviour which appears due to non-linear interactions within the system; emergence may be considered to be the 'product' or by-product of the system.
McDonald, D.M., Weir, G.R.S.
core   +1 more source

New Approaches to the Circle of Sense and Nonsense

open access: yesPhilosophies
I will briefly discuss the history of research-related projects that Mark Burgin and I worked on together. I will then discuss our joint research related to the circle of sense and nonsense.
Bill Seaman
doaj   +1 more source

Causal Emergence and Epiphenomenal Emergence [PDF]

open access: yesErkenntnis, 2018
According to one conception of strong emergence, strongly emergent properties are nomologically necessitated by their base properties and have novel causal powers relative to them. In this paper, I raise a difficulty for this conception of strong emergence, arguing that these two features (i.e., nomological necessitation and causal novelty) are ...
openaire   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

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