Results 41 to 50 of about 4,320,301 (409)

Osteopathic emergency medicine programs infrequently publish in high-impact emergency medicine journals [PDF]

, 2014
Introduction Both the Accreditation Council for Graduate Medical Education (ACGME) and the American Osteopathic Association (AOA) require core faculty to engage in scholarly work, including publication in peer-reviewed journals. With the ACGME/AOA merger,
Baskin, SM, Carlson, JN, Lin, C
core   +2 more sources

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Causality and Emergency Medicine? [PDF]

The Journal of Emergency Medicine, 2011
no ...
openaire   +4 more sources

An Evaluation of Risk Attitudes and Risk Tolerance in Emergency Medicine Residents [PDF]

, 2016
An underlying issue to our current healthcare system is how decisions made in the emergency department affect patients. This is paramount for underserved populations, which are more likely to have poor physical and mental health, lack of primary care ...
Papanagnou, MD, Dimitrios, Rahman, Nishad A.   +1 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Difference between how ambulance service personnel use paper and electronic patient care records when attending older people at home. [PDF]

, 2015
This is the accepted manuscript. This is a non-final version of an article published in final form in European Journal of Emergency Medicine. The final version is available from Wolters Kluwer at http://journals.lww.com/euro-emergencymed/Citation ...
Amador, Sarah, Buswell, Marina, Fleming, Jane, Goodman, Claire, Lumbard, Philip, Prothero, Larissa S.   +5 more
core   +3 more sources

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Farewell to a Friend - with "Love" [PDF]

, 2020
Peter Rosen, MD, FAAEM, one of the main founding fathers and mothers in the field of emergency medicine, passed away in Tucson, Arizona, on the 11th of November 2019 from complications of chronic diseases, with his best friend and wife Ann at his side ...
Kazzi, Amin
core  

The 2016 Academic Emergency Medicine Consensus Conference, Shared Decision Making in the Emergency Department: Development of a Policy-relevant Patient-centered Research Agenda Diagnostic Testing Breakout Session Report. [PDF]

, 2016
Diagnostic testing is an integral component of patient evaluation in the emergency department (ED). Emergency clinicians frequently use diagnostic testing to more confidently exclude worst-case diagnoses rather than to determine the most likely ...
Arterburn, Barton, Barton, Berkman, Charles, Edmonds, Elwyn, Elwyn, Flynn, Geyer, Gilbert, Gilbert, Hampers, Hess, Hess, Hess, Hoffman, Joseph-Williams, Jull, Jull, Kanzaria, Kanzaria, Katz, Kindermann, Kline, Kocher, Korley, Kripalani, Kutner, Larkin, Legare, Marin, Mitchell, O'Connor, Oshima Lee, Peterson, Rising, Rising, Schillinger, Sheehan, Stacey, Sudore, Venkatesh, Weiss, Weiss, Wharam, Wiener, Wolf, Wong   +48 more
core   +2 more sources