Results 21 to 30 of about 12,583 (231)

Emodin and aloe-emodin, two potential molecules in regulating cell migration of skin cells through the MAP kinase pathway and affecting Caenorhabditis elegans thermotolerance

BMC Molecular and Cell Biology, 2023
Background Emodin and aloe-emodin are two anthraquinones having positive effects in wound healing. However, their mechanism of action of wound healing is not fully understood.
Aysenur Gunaydin-Akyildiz, Rabia Sare Yanikoglu, Meltem Gulec, Gulbahar Ozge Alim-Toraman, Ebru Didem Kuran, Sezen Atasoy, Abdullah Olgun, Gulacti Topcu   +7 more
doaj   +1 more source

Forced degradation studies of aloe emodin and emodin by HPTLC

Indian Journal of Pharmaceutical Sciences, 2015
Anthraquinones are natural phenolic compounds, which are reported to act as anti-aging, anti-inflammatory, antioxidant, anti-cancer, laxative and antitumor agents. They are abudant in plants like candle bush, aloes, cascara bark and rhubarb. The present work was to observe the effect of different forced degradation conditions by high-performance thin ...
Sindhu, Narayanan, Aruna P, Jadhav, V J, Kadam   +2 more
openaire   +3 more sources

Bioconcentration and Metabolism of Emodin in Zebrafish Eleutheroembryos

Frontiers in Pharmacology, 2017
Emodin is a major active anthraquinone of various herbal laxatives, which can exert many pharmacological effects. However, chronic use of anthranoid laxatives, even at low dosages, may cause melanosis coli (MC).
Jiefeng Chen, Shaodong Li, Mengping Liu, Christopher Wai Kei Lam, Zheng Li, Xinjun Xu, Zuanguang Chen, Wei Zhang, Meicun Yao   +8 more
doaj   +1 more source

Selective Hydroxymethylation of Emodin [PDF]

Bulletin of the Chemical Society of Japan, 1991
Abstract Electrochemical oxidation of 1,3,8-trihydroxy-6-methylanthraquinone, emodin, in dry alkaline methanol under a constant current of 0.05 A for 10 h under an applied potential difference of 15 V at room temperature resulted, for the first time, in an efficient and selective hydroxymethylation at C-2.
Tarasankar Pal, Anjali Pal
openaire   +1 more source

Emodin-induced autophagic cell death hinders epithelial–mesenchymal transition via regulation of BMP-7/TGF-β1 in renal fibrosis

Journal of Pharmacological Sciences, 2021
We aim to explore the effects of emodin and its mechanisms on renal fibrosis (RF). We firstly modeled adriamycin-induced rat RF with unilateral nephrectomy. In vivo and in vitro pharmacological experiments were performed in this study.
Wei Liu, Renze Gu, Yujiao Lou, Chunfeng He, Qingchuan Zhang, Dongmei Li   +5 more
doaj   +1 more source

Antibiofilm efficacy of emodin alone or combined with ampicillin against methicillin-resistant Staphylococcus aureus. [PDF]

Sci Rep
Zhao M, Chen F, Yang W, Yan T, Chen Q.
europepmc   +3 more sources

Emodin Ameliorates Intestinal Dysfunction by Maintaining Intestinal Barrier Integrity and Modulating the Microbiota in Septic Mice

Mediators of Inflammation, 2022
Sepsis-induced inflammatory response leads to intestinal damage and secondary bacterial translocation, causing systemic infections and eventually death. Emodin is a natural anthraquinone derivative in many plants with promising bioactivities.
Mina Zhang, Bo Lian, Rui Zhang, Yuhong Guo, Jingxia Zhao, Shasha He, Yunjing Bai, Ning Wang, Yan Lin, Xuerui Wang, Qingquan Liu, Xiaolong Xu   +11 more
doaj   +1 more source

The p53-mediated cell cycle regulation is a potential mechanism for emodin-suppressing osteosarcoma cells

Heliyon
Background: As the most common primary bone cancer, the therapy of osteosarcoma requires further study. An anthraquinone derivative, emodin, has been found to have anticancer potential.
Qian Zhang, Shuli Hao, Guangyou Wei, Xiangyu Liu, Yang Miao   +4 more
doaj   +1 more source

Antibacterial Activity and Membrane-Targeting Mechanism of Aloe-Emodin Against Staphylococcus epidermidis

Frontiers in Microbiology, 2021
The emergence of multidrug-resistant Staphylococcus epidermidis (S. epidermidis) dwarfs the current antibiotic development and calls for the discovery of new antibacterial agents.
Tao Li, Yan Lu, Hua Zhang, Lei Wang, Ross C. Beier, Yajie Jin, Wenjing Wang, Huanrong Li, Xiaolin Hou   +8 more
doaj   +1 more source

Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ERαInhibition [PDF]

Evidence-Based Complementary and Alternative Medicine, 2013
The anthraquinones emodin and aloe-emodin are abundant in rhubarb. Several lines of evidence indicate that emodin and aloe-emodin have estrogenic activity as phytoestrogens. However, their effects on estrogen receptorα(ERα) activation and breast cancer cell growth remain controversial.
Pao-Hsuan Huang, Chih-Yang Huang, Mei-Chih Chen, Yueh-Tsung Lee, Chia-Herng Yue, Hsin-Yi Wang, Ho Lin   +6 more
openaire   +2 more sources