Results 121 to 130 of about 9,587,599 (304)

Early‐Life Manganese Overexposure Activates Microglial Phagocytosis through the YY1/TREM2 Axis Leading to Hippocampal Synaptic Remodeling in Mice

Advanced Science, EarlyView.
Early‐life manganese exposure induces behavioral deficits and aberrant hippocampal synaptic remodeling by enhancing microglial phagocytosis in young adult male mice. Mechanistically, manganese promotes Yin Yang 1 (YY1)/triggering receptor expressed on myeloid cells 2 (TREM2) signaling through enhanced HIF1α‐mediated transcription and suppressed SMURF2 ...
Keyu Chen, Bin He, Kuan Liu, Zhuo Ma, Bin Xu   +4 more
wiley   +1 more source

The “Emorality” of Caring: Validation of an Empirical Model of the Moral Feelings of Affective Care in Teaching Communities

Behavioral Sciences
This article presents a study that addresses the challenge of establishing a relationship between the axiological and the affective, by validating a structural model through an assessment instrument (SEMORCUNA) that isolates the moral feelings associated
Antonio Rodríguez-Hernández, Joaquín Sepúlveda-Aravena, Mariela Melgarejo-Coronel, Isabel Duarte Lores   +3 more
doaj   +1 more source

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

Advanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan, Tingmo Huang, Liyue Zeng, Ruixue Du, Hengshuo Zhang, Shen Liu, Tao Zhang, Jianzhong Hu, Hongbin Lu   +8 more
wiley   +1 more source

State education policies as a critical component of systemic SEL: Roger Weissberg’s vision and continuing impact

Social and Emotional Learning: Research, Practice, and Policy
What does it mean to promote social and emotional learning (SEL) across all 50 states? That was the visionary question of Dr. Roger Weissberg when he and the Collaborative for Academic, Social, and Emotional Learning (CASEL) set out to collaborate with ...
Nick Yoder, Caitlin Dermody, Andy Tucker, Asher A. Miller, Ruth Cross, Pat Conner, Dana Godek, Chi Kim, Linda Dusenbury   +8 more
doaj   +1 more source

Emotional Education in Early Onset Schizophrenia and Asperger's Syndrome. [PDF]

Behav Sci (Basel), 2020
Frolli A, Ricci MC, Tortorelli FA, Cavallaro A, Valenzano L, Rega A, Operto FF, Corrivetti G.   +7 more
europepmc   +1 more source

Predictors of rater bias in the assessment of social-emotional competence [PDF]

, 2016
The Devereux Student Strengths Assessment Mini (DESSA-Mini) (LeBuffe, Shapiro, & Naglieri, 2014) efficiently monitors the growth of Social-Emotional Competence (SEC) in the routine implementation of Social Emotional Learning programs. The DESSAMini is
Shapiro, Valerie B, Valerie B. Shapiro, Accomazzo, Sarah, B. K. Elizabeth Kim, Joe N. Roscoe, Sarah Accomazzo, Roscoe, Joe N., Shapiro, Valerie, Kim, Elizabeth B. K., Centre for Resilience & Socio-Emotional Health, Kim, BK Elizabeth, Roscoe, Joe N   +11 more
core   +1 more source

Arhgef1 Deletion Disrupts Early Cortical Neurogenesis via PAK1 Overactivation and Causes Motor Dysfunction in Adulthood

Advanced Science, EarlyView.
ARHGEF1 plays a pivotal role in both embryonic cortical neurogenesis and adult motor function. During early development, it governs genesis of deep‐layer cortical neurons by negatively regulating RAC1/CDC42‐PAK1‐Cofilin signaling. In adulthood, ARHGEF1 is important for the maintenance of neuronal morphology and activity in the motor cortex, ensuring ...
Liuren Li, Xuanyue Ma, Zhenyu Ding, Bang Sun, Linglin Liu, Hei Matthew Yip, Wei Wang, Tianying Wu, Yuan Guo, Yinghui Peng, Shiqing Zhang, Jacque Pak Kan Ip, Li Zhang, Keshen Li, Lei Shi   +14 more
wiley   +1 more source

A Novel Bioactive Component, Efoba, From Aged Garlic Targets CTSC to Suppress NET‐Driven Neuroinflammation and Ameliorate Secondary Brain Injury After Intracerebral Hemorrhage

Advanced Science, EarlyView.
Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng, Jianhua Wang, Tao Zhang, Xiaofan Fan, Jinxiu Guo, Shiyuan Zhao, Wenxue Sun, Pei Jiang   +7 more
wiley   +1 more source

Design, Implementation and Evaluation of an Emotional Education Program: Effects on Academic Performance. [PDF]

Front Psychol, 2020
Mira-Galvañ MJ, Gilar-Corbi R.
europepmc   +1 more source

Increasing Emotional Intelligence through Training: Current Status and Future Directions [PDF]

, 2013
Emotional intelligence consists of adaptive emotional functioning involving inter-related competencies relating to perception, understanding, utilising and managing emotions in the self and others.
Thorsteinsson, Einar B, John M. Malouff, Malouff, John M., Nicola S. Schutte, Einar B. Thorsteinsson, Malouff, John M, Schutte, Nicola S., Thorsteinsson, Einar B., Schutte, Nicola   +8 more
core   +1 more source