Results 1 to 10 of about 187,623 (239)
Emphysema Distribution and Diffusion Capacity Predict Emphysema Progression in Human Immunodeficiency Virus Infection. [PDF]
PLoS ONE, 2016 Chronic obstructive pulmonary disease (COPD) and emphysema are common amongst patients with human immunodeficiency virus (HIV). We sought to determine the clinical factors that are associated with emphysema progression in HIV.345 HIV-infected patients ...
Janice M Leung +11 more
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Association of automated quantified emphysema and interstitial lung abnormality with survival in non-small cell lung cancer [PDF]
Insights into ImagingObjectives To investigate the prognostic value of artificial intelligence (AI) quantified emphysema and interstitial lung abnormality (ILA) in patients with non-small cell lung cancer (NSCLC).
Guangjing Weng +7 more
doaj +2 more sources
Frequency and characteristics of emphysema in adults with FLNA variants: a single-center study [PDF]
Orphanet Journal of Rare DiseasesIntroduction FLNA pathogenic variants lead to various congenital malformations. Pulmonary manifestations were reported in early age. In adults, few cases of emphysema were published.
Arthur Michalski +15 more
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Respiratory Research, 2021 Many lung diseases are characterized by fibrosis, leading to impaired tissue patency and reduced lung function. Development of fibrotic tissue depends on two-way interaction between the cells and the extra-cellular matrix (ECM).
Peta Bradbury +8 more
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Journal of Experimental & Clinical Cancer Research, 2022 Background Cancer stem-like cells (CSCs) play a pivotal role in lung tumor formation and progression. Nerve injury-induced protein 1 (Ninjurin1, Ninj1) has been implicated in lung cancer; however, the pathological role of Ninj1 in the context of lung ...
Seung Yeob Hyun +11 more
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STAR Protocols, 2023 Summary: The slow-cycling subpopulation plays an important role in anticancer drug resistance and tumor recurrence. Here, we describe a clinically relevant patient-derived xenograft model and a carboxyfluorescein succinimidyl ester dye that is diluted in
Jaebeom Cho, Hye-Young Min, Ho-Young Lee
doaj +1 more source
Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases. [PDF]
, 2016 BACKGROUND: Emphysema is characterised by distinct pathological sub-types, but little is known about the divergent underlying aetiology. Matrix-metalloproteinases (MMPs) are proteolytic enzymes that can degrade the extracellular matrix and have been ...
Bourne, S +10 more
core +2 more sources
Respiratory Research, 2020 The role of the ATP binding cassette transporter A1 (ABCA1) in maintaining cellular lipid homeostasis in cardiovascular disease is well established. More recently, the important beneficial role played by ABCA1 in modulating pathogenic disease mechanisms,
Patrick He +2 more
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Emphysema Is Common in Lungs of Cystic Fibrosis Lung Transplantation Patients: A Histopathological and Computed Tomography Study. [PDF]
PLoS ONE, 2015 Lung disease in cystic fibrosis (CF) involves excessive inflammation, repetitive infections and development of bronchiectasis. Recently, literature on emphysema in CF has emerged, which might become an increasingly important disease component due to the ...
Onno M Mets +6 more
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Respiratory Research, 2019 Lung cancer (LC) has the highest relative risk of development as a comorbidity of chronic obstructive pulmonary disease (COPD). The molecular mechanisms that mediate chronic inflammation and lung function impairment in COPD have been identified in LC ...
Cassandra P. Nader +3 more
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