Results 1 to 10 of about 213,364 (422)
Automatic Emphysema Detection using Weakly Labeled HRCT Lung Images [PDF]
, 2017 A method for automatically quantifying emphysema regions using High-Resolution Computed Tomography (HRCT) scans of patients with chronic obstructive pulmonary disease (COPD) that does not require manually annotated scans for training is presented. HRCT scans of controls and of COPD patients with diverse disease severity are acquired at two different ...
Carl, Jesper +7 more
arxiv +10 more sources
Emphysema Distribution and Diffusion Capacity Predict Emphysema Progression in Human Immunodeficiency Virus Infection. [PDF]
PLoS ONE, 2016 Chronic obstructive pulmonary disease (COPD) and emphysema are common amongst patients with human immunodeficiency virus (HIV). We sought to determine the clinical factors that are associated with emphysema progression in HIV.345 HIV-infected patients ...
Janice M Leung +11 more
doaj +4 more sources
Polarized Helium to Image the Lung [PDF]
, 2005 The main findings of the european PHIL project (Polarised Helium to Image the Lung) are reported. State of the art optical pumping techniques for polarising ^3He gas are described. MRI methodological improvements allow dynamical ventilation images with a good resolution, ultimately limited by gas diffusion.
Leduc, Michèle, Nacher, Pierre-Jean
arxiv +7 more sources
Respiratory Research, 2019 Background The mechanisms underlying airflow obstruction in COPD cannot be distinguished by standard spirometry. We ascertain whether mathematical modeling of airway biomechanical properties, as assessed from spirometry, could provide estimates of ...
Mariaelena Occhipinti +12 more
doaj +2 more sources
Radiology, 2022 Background Given the different methods of assessing emphysema, controversy exists as to whether it is associated with lung cancer. Purpose To perform a systematic review and meta-analysis of the association between chest CT-defined emphysema and the ...
Xiaofei Yang +7 more
semanticscholar +1 more source
Respiratory Research, 2021 Many lung diseases are characterized by fibrosis, leading to impaired tissue patency and reduced lung function. Development of fibrotic tissue depends on two-way interaction between the cells and the extra-cellular matrix (ECM).
Peta Bradbury +8 more
doaj +1 more source
High-fiber diets attenuate emphysema development via modulation of gut microbiota and metabolism
Scientific Reports, 2021 Dietary fiber functions as a prebiotic to determine the gut microbe composition. The gut microbiota influences the metabolic functions and immune responses in human health.
Yoon Ok Jang +8 more
semanticscholar +1 more source
Journal of Experimental & Clinical Cancer Research, 2022 Background Cancer stem-like cells (CSCs) play a pivotal role in lung tumor formation and progression. Nerve injury-induced protein 1 (Ninjurin1, Ninj1) has been implicated in lung cancer; however, the pathological role of Ninj1 in the context of lung ...
Seung Yeob Hyun +11 more
doaj +1 more source
Emphysema Subtyping on Thoracic Computed Tomography Scans using Deep Neural Networks [PDF]
Sci Rep. 2023 Aug 29;13(1):14147, 2023 Accurate identification of emphysema subtypes and severity is crucial for effective management of COPD and the study of disease heterogeneity. Manual analysis of emphysema subtypes and severity is laborious and subjective. To address this challenge, we present a deep learning-based approach for automating the Fleischner Society's visual score system ...
arxiv +1 more source
Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases. [PDF]
, 2016 BACKGROUND: Emphysema is characterised by distinct pathological sub-types, but little is known about the divergent underlying aetiology. Matrix-metalloproteinases (MMPs) are proteolytic enzymes that can degrade the extracellular matrix and have been ...
Bourne, S +10 more
core +2 more sources