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Emphysema Distribution and Diffusion Capacity Predict Emphysema Progression in Human Immunodeficiency Virus Infection. [PDF]
PLoS ONE, 2016 Chronic obstructive pulmonary disease (COPD) and emphysema are common amongst patients with human immunodeficiency virus (HIV). We sought to determine the clinical factors that are associated with emphysema progression in HIV.345 HIV-infected patients ...
Janice M Leung +11 more
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Respiratory Research, 2021 Many lung diseases are characterized by fibrosis, leading to impaired tissue patency and reduced lung function. Development of fibrotic tissue depends on two-way interaction between the cells and the extra-cellular matrix (ECM).
Peta Bradbury +8 more
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Journal of Experimental & Clinical Cancer Research, 2022 Background Cancer stem-like cells (CSCs) play a pivotal role in lung tumor formation and progression. Nerve injury-induced protein 1 (Ninjurin1, Ninj1) has been implicated in lung cancer; however, the pathological role of Ninj1 in the context of lung ...
Seung Yeob Hyun +11 more
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Respiratory Research, 2020 The role of the ATP binding cassette transporter A1 (ABCA1) in maintaining cellular lipid homeostasis in cardiovascular disease is well established. More recently, the important beneficial role played by ABCA1 in modulating pathogenic disease mechanisms,
Patrick He +2 more
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Emphysema Is Common in Lungs of Cystic Fibrosis Lung Transplantation Patients: A Histopathological and Computed Tomography Study. [PDF]
PLoS ONE, 2015 Lung disease in cystic fibrosis (CF) involves excessive inflammation, repetitive infections and development of bronchiectasis. Recently, literature on emphysema in CF has emerged, which might become an increasingly important disease component due to the ...
Onno M Mets +6 more
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BMJ, 2006 Emphysema affects 3.1 million people in the United States alone and causes severe disability and early death in up to 45% of patients.1 Emphysematous destruction of the lung is associated with decreased elastic recoil pressure. As a result, the diseased lung requires less pressure than a normal lung to inflate and, once inflated, exerts less pressure ...
VENUTA, Federico, G. Bognolo
openaire +3 more sources
Respiratory Research, 2019 Lung cancer (LC) has the highest relative risk of development as a comorbidity of chronic obstructive pulmonary disease (COPD). The molecular mechanisms that mediate chronic inflammation and lung function impairment in COPD have been identified in LC ...
Cassandra P. Nader +3 more
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Diagnosing and mapping pulmonary emphysema on X-ray projection images [PDF]
, 2013 To assess whether grating-based X-ray dark-field imaging can increase the sensitivity of X-ray projection images in the diagnosis of pulmonary emphysema and allow for a more accurate assessment of emphysema distribution.
Achterhold, Klaus +16 more
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Eosinophils promote pulmonary matrix destruction and emphysema via Cathepsin L
Signal Transduction and Targeted Therapy, 2023 Patients with chronic obstructive pulmonary disease (COPD) who exhibit elevated blood eosinophil levels often experience worsened lung function and more severe emphysema.
Xia Xu +14 more
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