Results 91 to 100 of about 213,364 (422)
Exercise intolerance and systemic manifestations of pulmonary emphysema in a mouse model
Background Systemic effects of chronic obstructive pulmonary disease (COPD) significantly contribute to severity and mortality of the disease. We aimed to develop a COPD/emphysema model exhibiting systemic manifestations of the disease.
Hasenfuss Gerd+6 more
doaj +1 more source
Alveolar macrophages and the diagnosis of drowning [PDF]
In the present study, we examined the number of alveolar macrophages in lung tissue from 17 cases of fresh water drowning, 22 cases of acute death and 6 cases of lung emphysema.
A. Nerlich+12 more
core +1 more source
BackgroundMitochondrial damage leading to oxidant stress may play an important role in the pathogenesis of airflow obstruction and emphysema. NLPR3 inflammasome can be activated by mitochondrial ROS (mtROS) and other stimuli.
Feng Li+11 more
semanticscholar +1 more source
Diagnosing the first patient: Integrating histopathology into an undergraduate gross anatomy course
Abstract The incorporation of humanism through exploration of pathology in gross anatomy allows students to develop a deeper appreciation of the pathological basis of disease and to explore the impacts of pathology on donors' lives through clinicopathologic correlation of their findings.
Kyle A. Robertson+2 more
wiley +1 more source
Features of transbronchial lung cryobiopsy‐diagnosed fibrotic hypersensitivity pneumonitis
This study describes the clinical and pathological features of fibrotic hypersensitivity pneumonitis diagnosed with transbronchial lung crybiopsy. Usual interstitial pneumonia was the most frequent pathological finding of fibrotic hypersensitivity pneumonitis.
Xi Zhan+14 more
wiley +1 more source
Weak Supervision in Convolutional Neural Network for Semantic Segmentation of Diffuse Lung Diseases Using Partially Annotated Dataset [PDF]
Computer-aided diagnosis system for diffuse lung diseases (DLDs) is necessary for the objective assessment of the lung diseases. In this paper, we develop semantic segmentation model for 5 kinds of DLDs. DLDs considered in this work are consolidation, ground glass opacity, honeycombing, emphysema, and normal.
arxiv +1 more source
Allosteric modulation of beta1 integrin function induces lung repair in animal model of emphysema. [PDF]
Emphysema is a progressive lung disease characterised by loss of lung parenchyma with associated functional changes including decreased tissue elastance. Here we report beta1 integrin is a novel target for tissue repair and regeneration in emphysema.
Chris J. Armit+6 more
core +1 more source
Local lung responses following endobronchial elastase and lipopolysaccharide instillation in sheep [PDF]
Chronic lipopolysaccharide (LPS) exposure may contribute to the pathogenesis of a number of lung diseases including COPD and emphysema. We sought to develop a large- animal model of emphysema using repeated LPS administration into sheep lung segments. An
Baker, Alison+7 more
core +2 more sources
Tobacco smoking (TS) is implicated in lung cancer (LC) progression through the development of metabolic syndrome. However, direct evidence linking metabolic syndrome to TS-mediated LC progression remains to be established. Our findings demonstrate that 4-
Hyun-Ji Jang+11 more
doaj +1 more source