Results 21 to 30 of about 219,949 (396)

Protein phosphatase 2A (PP2A): a key phosphatase in the progression of chronic obstructive pulmonary disease (COPD) to lung cancer

open access: yesRespiratory Research, 2019
Lung cancer (LC) has the highest relative risk of development as a comorbidity of chronic obstructive pulmonary disease (COPD). The molecular mechanisms that mediate chronic inflammation and lung function impairment in COPD have been identified in LC ...
Cassandra P. Nader   +3 more
doaj   +1 more source

Automatic Emphysema Detection using Weakly Labeled HRCT Lung Images [PDF]

open access: yes, 2018
A method for automatically quantifying emphysema regions using High-Resolution Computed Tomography (HRCT) scans of patients with chronic obstructive pulmonary disease (COPD) that does not require manually annotated scans for training is presented.
Carl, Jesper   +7 more
core   +7 more sources

Eosinophils promote pulmonary matrix destruction and emphysema via Cathepsin L

open access: yesSignal Transduction and Targeted Therapy, 2023
Patients with chronic obstructive pulmonary disease (COPD) who exhibit elevated blood eosinophil levels often experience worsened lung function and more severe emphysema.
Xia Xu   +14 more
doaj   +1 more source

Subcutaneous emphysema during root canal therapy: endodontic accident by sodium hypoclorite [PDF]

open access: yes, 2017
Cervicofacial subcutaneous emphysema is defined as the abnormal introduction of air in the subcutaneous tissues of the head and neck. It is mainly caused by trauma, head and neck surgery, general anesthesia, and coughing or habitual performance of ...
Battisti, Andrea   +5 more
core   +1 more source

Fecal microbial transplantation and a high fiber diet attenuates emphysema development by suppressing inflammation and apoptosis

open access: yesExperimental and Molecular Medicine, 2020
Recent work has suggested a microbial dysbiosis association between the lung and gut in respiratory diseases. Here, we demonstrated that gut microbiome modulation attenuated emphysema development.
Yoon Ok Jang   +9 more
semanticscholar   +1 more source

Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers.

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2020
BACKGROUND The relative roles of mucus plugs and emphysema in mechanisms of airflow limitation and hypoxemia in smokers with chronic obstructive pulmonary disease (COPD) are uncertain.
E. Dunican   +33 more
semanticscholar   +1 more source

Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation [PDF]

open access: yes, 2011
Deficiency of vitamin D is associated with accelerated decline in lung function. Vitamin D is a ligand for nuclear hormone vitamin D receptor (VDR), and upon binding it modulates various cellular functions.
Hwang, Jae-woong   +4 more
core   +1 more source

CT Assessment of Subtypes of Pulmonary Emphysema in Mongolian Miners

open access: yesCentral Asian Journal of Medical Sciences, 2020
Objectives: To determine the incidence of subtypes of pulmonary emphysema identified by LDCT imaging and the relationship between emphysema subtypes with smoking and pulmonary function in miners.
Garamjav Khishigdavaa   +7 more
doaj   +1 more source

Association Between Air Pollution and Lung Lobar Emphysema in COPD

open access: yesFrontiers in Medicine, 2021
The development of emphysema has been linked to air pollution; however, the association of air pollution with the extent of lobar emphysema remains unclear.
Nguyen Thanh Tung   +22 more
doaj   +1 more source

A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema.

open access: yesNew England Journal of Medicine, 2003
BACKGROUND Lung-volume-reduction surgery has been proposed as a palliative treatment for severe emphysema. Effects on mortality, the magnitude and durability of benefits, and criteria for the selection of patients have not been established.
A. Fishman   +7 more
semanticscholar   +1 more source

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