Results 21 to 30 of about 188,190 (286)

Development of a 4-aminopyrazolo[3,4-d]pyrimidine-based dual IGF1R/Src inhibitor as a novel anticancer agent with minimal toxicity

open access: yesMolecular Cancer, 2018
Background Both the type I insulin-like growth factor receptor (IGF1R) and Src pathways are associated with the development and progression of numerous types of human cancer, and Src activation confers resistance to anti-IGF1R therapies. Hence, targeting
Ho Jin Lee   +8 more
doaj   +1 more source

Diagnosing and mapping pulmonary emphysema on X-ray projection images [PDF]

open access: yes, 2013
To assess whether grating-based X-ray dark-field imaging can increase the sensitivity of X-ray projection images in the diagnosis of pulmonary emphysema and allow for a more accurate assessment of emphysema distribution.
Achterhold, Klaus   +16 more
core   +1 more source

Pulmonary Emphysema: Visual Interpretation and Quantitative Analysis

open access: yes대한영상의학회지, 2021
Pulmonary emphysema is a cause of chronic obstructive pulmonary disease. Emphysema can be accurately diagnosed via CT. The severity of emphysema can be assessed using visual interpretation or quantitative analysis.
Jihang Kim
doaj   +1 more source

Comorbid Conditions in Idiopathic Pulmonary Fibrosis: Recognition and Management. [PDF]

open access: yes, 2017
Idiopathic pulmonary fibrosis (IPF), a fibrosing interstitial pneumonia of unknown etiology, primarily affects older adults and leads to a progressive decline in lung function and quality of life.
Collard, Harold R, Oldham, Justin M
core   +2 more sources

Pulmonary artery stiffness in chronic obstructive pulmonary disease (copd) and emphysema: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study [PDF]

open access: yes, 2018
Purpose: Chronic obstructive pulmonary disease (COPD) and particularly emphysema are characterized by stiffness of the aorta, due in part to accelerated elastin degradation in the lungs and aorta. Stiffness of the pulmonary arteries (PAs) may also be
Balte, Pallavi   +12 more
core   +1 more source

Association between plasma sRAGE and emphysema according to the genotypes of AGER gene

open access: yesBMC Pulmonary Medicine, 2022
Background Higher soluble receptor for advanced glycation end product (sRAGE) levels are considered to be associated with severe emphysema. However, the relationship remains uncertain when the advanced glycation end-product specific receptor (AGER) gene ...
Sooim Sin   +4 more
doaj   +1 more source

Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression [PDF]

open access: yes, 2010
Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic bronchitis, emphysema and irreversible airflow limitation. These changes are thought to be due to oxidative stress and an imbalance of proteases and antiproteases ...
A Babusyte   +63 more
core   +6 more sources

Basilar Predominant Emphysema: Thinking beyond Alpha-1-Antitrypsin Deficiency

open access: yesCase Reports in Medicine, 2022
Basilar predominant emphysema, or disproportionate emphysematous involvement of the lung bases compared to the apices, is an uncommon radiographic pattern of emphysema traditionally associated with alpha-1-antitrypsin deficiency (AATD). We present a case
Ho-Man Yeung, Lauren Gaffaney
doaj   +1 more source

Risk factors of pneumothorax and chest tube placement after computed tomography-guided core needle biopsy of lung lesions : a single-centre experience with 822 biopsies [PDF]

open access: yes, 2018
Purpose: To determine the risk factors of pneumothorax and chest tube placement after computed tomography-guided core needle lung biopsy (CT-CNB). Material and methods: Variables that could increase the risk of pneumothorax and chest tube placement were ...
Gokalp, Gokhan   +3 more
core   +1 more source

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