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Food Science &Nutrition, Volume 11, Issue 1, Page 390-407, January 2023., 2023 COPD aggravates AS, possibly through the destruction of pulmonary microvascular barrier function; thus, lung inflammation triggers systemic inflammation. In treating COPD with AS, TXL enhances the antiatherosclerotic effect of Ato, protecting the pulmonary microvascular barrier.
Xiangnan Kuang +11 more
wiley +1 more source
Rare surfactant‐related variants in familial and sporadic pulmonary fibrosis
Human Mutation, Volume 43, Issue 12, Page 2091-2101, December 2022., 2022 Abstract The role of constitutional genetic defects in idiopathic pulmonary fibrosis (IPF) is increasingly appreciated. Monogenic disorders associated with IPF affect two pathways: telomere maintenance, accounting for approximately 10% of all patients with IPF, and surfactant biology, responsible for 1%–3% of cases and often co‐occurring with lung ...
Rachel M. Sutton +10 more
wiley +1 more source
Emphysema Is Common in Lungs of Cystic Fibrosis Lung Transplantation Patients: A Histopathological and Computed Tomography Study. [PDF]
PLoS ONE, 2015 Lung disease in cystic fibrosis (CF) involves excessive inflammation, repetitive infections and development of bronchiectasis. Recently, literature on emphysema in CF has emerged, which might become an increasingly important disease component due to the ...
Onno M Mets +6 more
doaj +1 more source
BMJ, 2006 Emphysema affects 3.1 million people in the United States alone and causes severe disability and early death in up to 45% of patients.1 Emphysematous destruction of the lung is associated with decreased elastic recoil pressure. As a result, the diseased lung requires less pressure than a normal lung to inflate and, once inflated, exerts less pressure ...
VENUTA, Federico, G. Bognolo
openaire +3 more sources
Respiratory Research, 2019 Lung cancer (LC) has the highest relative risk of development as a comorbidity of chronic obstructive pulmonary disease (COPD). The molecular mechanisms that mediate chronic inflammation and lung function impairment in COPD have been identified in LC ...
Cassandra P. Nader +3 more
doaj +1 more source
Eosinophils promote pulmonary matrix destruction and emphysema via Cathepsin L
Signal Transduction and Targeted Therapy, 2023 Patients with chronic obstructive pulmonary disease (COPD) who exhibit elevated blood eosinophil levels often experience worsened lung function and more severe emphysema.
Xia Xu +14 more
doaj +1 more source
Xeroderma Pigmentosum Group C Deficiency Alters Cigarette Smoke DNA Damage Cell Fate and Accelerates Emphysema Development [PDF]
, 2018 Cigarette smoke (CS) exposure is a major risk factor for the development of emphysema, a common disease characterized by loss of cells comprising the lung parenchyma.
Fisher, Amanda J. +8 more
core +1 more source
Experimental and Molecular Medicine, 2020 Recent work has suggested a microbial dysbiosis association between the lung and gut in respiratory diseases. Here, we demonstrated that gut microbiome modulation attenuated emphysema development.
Yoon Ok Jang +9 more
semanticscholar +1 more source
Association Between Air Pollution and Lung Lobar Emphysema in COPD
Frontiers in Medicine, 2021 The development of emphysema has been linked to air pollution; however, the association of air pollution with the extent of lobar emphysema remains unclear.
Nguyen Thanh Tung +22 more
doaj +1 more source
Diagnosing and mapping pulmonary emphysema on X-ray projection images [PDF]
, 2013 To assess whether grating-based X-ray dark-field imaging can increase the sensitivity of X-ray projection images in the diagnosis of pulmonary emphysema and allow for a more accurate assessment of emphysema distribution.
Achterhold, Klaus +16 more
core +1 more source