Results 31 to 40 of about 231,498 (381)

A circadian based inflammatory response – implications for respiratory disease and treatment

Sleep Science and Practice, 2017
Circadian clocks regulate the daily timing of many of our physiological, metabolic and biochemical functions. The immune system also displays circadian oscillations in immune cell count, synthesis and cytokine release, clock gene expression in cells and ...
Maria Comas, Christopher J. Gordon, Brian G. Oliver, Nicholas W. Stow, Gregory King, Pawan Sharma, Alaina J. Ammit, Ronald R. Grunstein, Craig L. Phillips   +8 more
doaj   +1 more source

Pathogenesis of chronic obstructive pulmonary disease [PDF]

, 2005
The current paradigm for the pathogenesis of chronic obstructive pulmonary disease is that chronic airflow limitation results from an abnormal inflammatory response to inhaled particles and gases in the lung. Airspace inflammation appears to be different
Macnee, W
core   +2 more sources

Pulmonary Emphysema: Visual Interpretation and Quantitative Analysis

대한영상의학회지, 2021
Pulmonary emphysema is a cause of chronic obstructive pulmonary disease. Emphysema can be accurately diagnosed via CT. The severity of emphysema can be assessed using visual interpretation or quantitative analysis.
Jihang Kim
doaj   +1 more source

Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression [PDF]

, 2010
Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic bronchitis, emphysema and irreversible airflow limitation. These changes are thought to be due to oxidative stress and an imbalance of proteases and antiproteases ...
A Babusyte, A Kode, A Papi, A Sebastian, A Sydbom, AP Rogerio, AW Boots, C Kandaswami, C Tabak, CJ Vlahos, D Nowak, DC Newcomb, EH Walker, G Agullo, GA Finlay, GW Peet, HJ Park, HS Deshmukh, HS Deshmukh, I Rahman, IC Walda, IK Demedts, J Robak, JA Conquer, JC Chen, JD Hasday, JH Vernooy, JW Hwang, K Ito, K Minamoto, K Ohnishi, KF Chung, KK Meja, L Biasutto, L Larsson, L Segura-Valdez, M Comalada, M Harwood, M Ichinose, M Kasielski, M Suzuki, MK Hwang, MM Mu, N Louhelainen, O Michel, P Maestrelli, P Santus, PC Hollman, PF Mercer, PJ Jagielo, R Mahadeva, S Nanua, S Rajendrasozhan, S Shishodia, SK Biswas, SP Davies, SV Culpitt, T Shinohara, T Zheng, U Sajjan, W MacNee, Y Kaneko, Y Nakamaru, Y-T Huang   +63 more
core   +6 more sources

Development of a 4-aminopyrazolo[3,4-d]pyrimidine-based dual IGF1R/Src inhibitor as a novel anticancer agent with minimal toxicity

Molecular Cancer, 2018
Background Both the type I insulin-like growth factor receptor (IGF1R) and Src pathways are associated with the development and progression of numerous types of human cancer, and Src activation confers resistance to anti-IGF1R therapies. Hence, targeting
Ho Jin Lee, Phuong Chi Pham, Seung Yeob Hyun, Byungyeob Baek, Byungjin Kim, Yunha Kim, Hye-Young Min, Jeeyeon Lee, Ho-Young Lee   +8 more
doaj   +1 more source

n-3系脂肪散を強化した食事療法が有効と考えられた肺気腫の一例 [PDF]

, 1998
An effective treatment for the advanced stages of chronic obstructive pulmonary disease (COPD) has not been established yet. We report our recent experience of one patient with pulmonary emphysema treated by dietary supplementation of n-3 fatty acid for ...
Ashida, Kozo, Hosaki, Yasuhiro, Mifune, Takashi, Mitsunobu, Fumihiro, Okamoto, Makoto, Tanizaki, Yoshiro, Tsugeno, Hirofumi, Tsuji, Takao   +7 more
core   +1 more source

Association between plasma sRAGE and emphysema according to the genotypes of AGER gene

BMC Pulmonary Medicine, 2022
Background Higher soluble receptor for advanced glycation end product (sRAGE) levels are considered to be associated with severe emphysema. However, the relationship remains uncertain when the advanced glycation end-product specific receptor (AGER) gene ...
Sooim Sin, Myung-nam Lim, Jeeyoung Kim, So Hyeon Bak, Woo Jin Kim   +4 more
doaj   +1 more source

Attitudes and access to lung volume reduction surgery for COPD: a survey by the British Thoracic Society. [PDF]

, 2014
OBJECTIVE: Lung volume reduction surgery for emphysema leads to improved survival in appropriately selected individuals, and it is therefore recommended in national and international guidelines for this group of patients.
Hopkinson, NS, Jordan, S, McNulty, W
core   +1 more source

Fleischner Society Visual Emphysema CT Patterns Help Predict Progression of Emphysema in Current and Former Smokers: Results from the COPDGene Study.

Radiology, 2020
Background The correlation between visual emphysema patterns and subsequent progression of disease may provide a way to enrich a study population for treatment trials of emphysema.
Bilal El Kaddouri, M. Strand, D. Baraghoshi, S. Humphries, J. Charbonnier, E. V. van Rikxoort, D. Lynch   +6 more
semanticscholar   +1 more source

Diagnosing and mapping pulmonary emphysema on X-ray projection images [PDF]

, 2013
To assess whether grating-based X-ray dark-field imaging can increase the sensitivity of X-ray projection images in the diagnosis of pulmonary emphysema and allow for a more accurate assessment of emphysema distribution.
Achterhold, Klaus, Auweter, Sigrid, Bamberg, Fabian, Bech, Martin, Bohla, Alexander, Eickelberg, Oliver, Gifford, Martin, Herzen, Julia, Loewen, Rod, Meinel, Felix G., Nikolaou, Konstantin, Pfeiffer, Franz, Reiser, Maximilian F., Ruth, Ronald, Schleede, Simone, Schwab, Felix, Yildirim, Ali Ö.   +16 more
core   +1 more source