Results 31 to 40 of about 213,364 (422)

Association Between Long-term Exposure to Ambient Air Pollution and Change in Quantitatively Assessed Emphysema and Lung Function.

Journal of the American Medical Association (JAMA), 2019
Importance While air pollutants at historical levels have been associated with cardiovascular and respiratory diseases, it is not known whether exposure to contemporary air pollutant concentrations is associated with progression of emphysema ...
Meng Wang, C. P. Aaron, Jaime Madrigano, Eric A. Hoffman, E. Angelini, Jie Yang, A. Laine, Thomas M Vetterli, Patrick L. Kinney, Paul D. Sampson, L. Sheppard, A. Szpiro, S. Adar, K. Kirwa, Benjamin M. Smith, David J Lederer, A. Diez-Roux, S. Vedal, Joel D. Kaufman, R. G. Barr   +19 more
semanticscholar   +1 more source

Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers.

American Journal of Respiratory and Critical Care Medicine, 2020
BACKGROUND The relative roles of mucus plugs and emphysema in mechanisms of airflow limitation and hypoxemia in smokers with chronic obstructive pulmonary disease (COPD) are uncertain.
E. Dunican, Brett M. Elicker, T. Henry, D. Gierada, M. Schiebler, W. Anderson, I. Barjaktarevic, R. G. Barr, E. Bleecker, Richard C. Boucher, R. Bowler, S. Christenson, A. Comellas, C. Cooper, D. Couper, Gerard J. Criner, M. Dransfield, Claire M. Doerschuk, M. B. Drummond, N. Hansel, M. Han, Annette T. Hastie, Eric A. Hoffman, Jerry A Krishnan, Stephen C. Lazarus, F. Martinez, Charles E. McCulloch, W. O’Neal, Victor E. Ortega, R. Paine, S. Peters, J. Schroeder, Prescott G. Woodruff, J. Fahy   +33 more
semanticscholar   +1 more source

Pulmonary artery stiffness in chronic obstructive pulmonary disease (copd) and emphysema: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study [PDF]

, 2018
Purpose: Chronic obstructive pulmonary disease (COPD) and particularly emphysema are characterized by stiffness of the aorta, due in part to accelerated elastin degradation in the lungs and aorta. Stiffness of the pulmonary arteries (PAs) may also be
Balte, Pallavi, Barr, R. Graham, Bluemke, David A., Carr, James, Dashnaw, Stephen, Gomes, Antoinette S., Hoffman, Eric A., Kawut, Steven M., Lima, Joao A.C., Liu, Chia-Ying, McAllister, David A., Parikh, Megha, Poor, Hooman D.   +12 more
core   +1 more source

CT Assessment of Subtypes of Pulmonary Emphysema in Mongolian Miners

Central Asian Journal of Medical Sciences, 2020
Objectives: To determine the incidence of subtypes of pulmonary emphysema identified by LDCT imaging and the relationship between emphysema subtypes with smoking and pulmonary function in miners.
Garamjav Khishigdavaa, Ichinnorov Dashtseren, Tuvshinjargal Dashjamts, Buyankhishig Lhagvatogoo, Naidan Nyamkhuu, Oyunchimeg Dookhuu, Gonchigsuren Dagvasumberel, Bayasgalan Gombojav   +7 more
doaj   +1 more source

Development of a 4-aminopyrazolo[3,4-d]pyrimidine-based dual IGF1R/Src inhibitor as a novel anticancer agent with minimal toxicity

Molecular Cancer, 2018
Background Both the type I insulin-like growth factor receptor (IGF1R) and Src pathways are associated with the development and progression of numerous types of human cancer, and Src activation confers resistance to anti-IGF1R therapies. Hence, targeting
Ho Jin Lee, Phuong Chi Pham, Seung Yeob Hyun, Byungyeob Baek, Byungjin Kim, Yunha Kim, Hye-Young Min, Jeeyeon Lee, Ho-Young Lee   +8 more
doaj   +1 more source

Subcutaneous emphysema during root canal therapy: endodontic accident by sodium hypoclorite [PDF]

, 2017
Cervicofacial subcutaneous emphysema is defined as the abnormal introduction of air in the subcutaneous tissues of the head and neck. It is mainly caused by trauma, head and neck surgery, general anesthesia, and coughing or habitual performance of ...
Battisti, Andrea, Ciolfi, Chiara, Mohsen, Mohamed, Palaia, Gaspare, Romeo, Umberto, Tenore, Gianluca   +5 more
core   +1 more source

A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema.

New England Journal of Medicine, 2003
BACKGROUND Lung-volume-reduction surgery has been proposed as a palliative treatment for severe emphysema. Effects on mortality, the magnitude and durability of benefits, and criteria for the selection of patients have not been established.
A. Fishman, F. Martinez, K. Naunheim, S. Piantadosi, R. Wise, A. Ries, G. Weinmann, D. Wood   +7 more
semanticscholar   +1 more source

Pulmonary Emphysema: Visual Interpretation and Quantitative Analysis

대한영상의학회지, 2021
Pulmonary emphysema is a cause of chronic obstructive pulmonary disease. Emphysema can be accurately diagnosed via CT. The severity of emphysema can be assessed using visual interpretation or quantitative analysis.
Jihang Kim
doaj   +1 more source

Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation [PDF]

, 2011
Deficiency of vitamin D is associated with accelerated decline in lung function. Vitamin D is a ligand for nuclear hormone vitamin D receptor (VDR), and upon binding it modulates various cellular functions.
Hwang, Jae-woong, Rahman, Irfan, Sun, Jun, Sundar, Isaac K, Wu, Shaoping   +4 more
core   +1 more source

Cigarette smoke-induced autophagy impairment accelerates lung aging, COPD-emphysema exacerbations and pathogenesis.

American Journal of Physiology - Cell Physiology, 2018
Cigarette-smoke (CS) exposure and aging are the leading causes of chronic obstructive pulmonary disease (COPD)-emphysema development, although the molecular mechanism that mediates disease pathogenesis remains poorly understood.
N. Vij, P. Chandramani-Shivalingappa, Colin Van Westphal, R. Hole, M. Bodas   +4 more
semanticscholar   +1 more source