Results 51 to 60 of about 694,998 (286)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Aplikasi Sistem Pendukung Keputusan Penilaian Kinerja Karyawan untuk Kenaikan Gaji pada PT AAA
Intensif: Jurnal Ilmiah Penelitian Teknologi dan Penerapan Sistem Informasi, 2017 PT AAA is a company engaged in the process of instrumentation and electrical design, procurement and construction of instruments. In an effort to improve employee performance PT AAA provide salary increase to employees who have good performance.
Adhika Pramita Widyassari
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Akofena: This study aimed to measure the impact of human resource management strategies-specifically recruitment strategy, training and development strategy, performance appraisal strategy, and motivation strategy—on improving employee performance at Ahmed ...
Abdelkader TALHA, Abdelkader MAKHLOUF, Kada YAZID & Abdelkrim MERAHI
doaj +1 more source
Frontiers in PsychologySupervisory feedback to stimulate research and development (R&D) employee creativity is a management issue that concerns scholars and practitioners.
Haihong Li +5 more
doaj +1 more source
Factors influencing managers’ attitudes towards performance appraisal
SA Journal of Human Resource Management, 2017 Orientation: Managers often have negative attitudes towards performance appraisal because of its problematic nature, which is influenced by political and social contextual factors.
Tanya du Plessis, Annelize van Niekerk
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Performance Appraisal: Dimensions and Determinants [PDF]
The determinants of the dimensions that shape a formal system of performance appraisal are studied in relation to a sample of Spanish manufacturing establishments.
Galdón-Sánchez, José Enrique +2 more
core