Results 101 to 110 of about 334,116 (311)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Pengaruh Kepribadian, Kemampuan Dan Disiplin Kerja Terhadap Kinerja Karyawan PT. Suryamas Citra Lestari Cabang Surakarta [PDF]

, 2016
The purpose of this study was to investigate the influence of personality, ability and discipline on employee performance. The population of this research at PT. Suryamas Citra Lestari Surakarta branch. Processing of data by means of SPSS. The results of
, Dr. Rini Kuswati, S.E., M.Si, Santoso, Wahyu Aji   +1 more
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Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

PENGARUH KEPEMIMPINAN DAN DISIPLIN KERJA TERHADAP KINERJA KARYAWAN PADA PT CENTRAL CAPITAL FUTURES CABANG MALANG

Jurnal Ilmiah Bisnis dan Ekonomi Asia, 2018
This study aims to determine: (1). The influence of leadership on employee performance of PT Central Capital Futures Malang Branch; (2). The influence of work discipline on employee performance of PT Central Capital Futures Malang Branch; (3).
Any Isvandiari, Bagus Al Idris
doaj   +1 more source

Analisis Disiplin Kerja Pegawai pada Dinas Pengelolaan Keuangan dan Aset (Dpka) Kabupaten Rokan Hulu [PDF]

, 2015
Syahrial, 1025096, 2015, the analysis of employee discipline in the financial services and asset management (DPKA) Rokan Hulu district, Anal, Supervisor I Welven Aida, S.Pd, M.Pd dan Supervisor II Asrori, S.Pd, MM.The aim of this research is to know what
Syahrial, S. (Syahrial)
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Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Employee Performance: Leadership Styles, Discipline and Motivation

Dinasti International Journal of Management Science, 2023
Leadership style is a factor that determines the development of an organization . Work discipline and motivation are determining factors of the employee’s performance. This study aims to describe and examine the influence of leadership style, discipline, and motivation variables on employee performance.
openaire   +1 more source

Pengaruh Kepemimpinan dan Disiplin Kerja terhadap Kinerja Karyawan pada Perum Perumnas Regional V Semarang [PDF]

, 2015
Human resource management plays an active role in improving employee performance through a number of variables that influence it, including the leadership, work discipline and employee performance. Perum Perumnas Regional V Semarang is one public company
Nugraha, H. S. (Hari), Safitri, A. R. (Ayu), Widiartanto, W. (Widiartanto)   +2 more
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Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Pengaruh Disiplin Kerja Dan Kemampuan Kerja Terhadap Prestasi Kerja Karyawan (Studi Pada Pegawai Kantor Pusat PT Pelabuhan Indonesia III (Persero) Surabaya) [PDF]

, 2013
The purpose of this study were to determine the effect of Labor Dicipline and The Ability to work on employee performance simultaneously and partially at the Head Office of PT Pelabuhan Indonesia III Persero Surabaya.
Rahmawati, A. H. (Aulia)
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