Results 51 to 60 of about 1,043,884 (276)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Office of Injured Employee Counsel Quarterly Review

open access: yes, 2011
Quarterly newsletter discussing the activities of the Office of Injured Employee Counsel in ...
Texas. Office of Injured Employee Counsel.
core   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

THE INFLUENCE OF WORK BALANCE, WORK DISCIPLINE, AND EMPLOYEE MOTIVATION ON EMPLOYEE PERFORMANCE OF AUTOMOTIVE CARS IN PALOPO CITY

open access: yesJournal of Management Small and Medium Enterprises (SME's)
This study aims to investigate the effect of work balance, work discipline, and employee motivation on the performance of Palopo city car automotive employees. The method used in this research is a quantitative method.
Nurhayani Nurhayani   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

PENGARUH INDIVIDU DAN ORGANISASI TERHADAP DISIPLIN KERJA (Studi Pada PT. Bank “X” Cabang “Y” Malang)

open access: yesWacana: Jurnal Sosial dan Humaniora, 2012
  Work discipline is the condition desired by organization. Work discipline will never be happened automatically, but should be shaped by many factors, both individual and organizational factors.
Laily Kristianawati   +2 more
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

THE INFLUENCE OF SERVANT LEADERSHIP, WORKLOAD AND WORK DISCIPLINE ON THE PERFORMANCE OF REGIONAL COMPANY EMPLOYEES IN WEST JAVA

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics
This study aims to analyze the influence of leadership style (servant leadership), workload, and work discipline on employee performance in Regional Companies in West Java.
Viky Prayuga   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Effect of Work Discipline and Training on Employee Performance of PT Federal International Finance Depok Branch

open access: yesJurnal Ilmiah Ilmu Administrasi Publik, 2020
This study aims to determine the effect of work discipline and training on employee performance at PT. Federal International Finance Depok Branch.
Agrasadya Agrasadya
doaj   +1 more source

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