By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Work Discipline, Work Motivation and Employee Performance
Advances in Human Resource Management Research, 2023 This study's objective was to examine and ascertain the impact of discipline and work motivation on employee performance at PT Trans Kalla Makassar. All 321 employees at PT Trans Kalla Makassar constitute the population of this investigation. Based on the slovin formulation, the number of samples used was as high as 76 respondents.
Sandra Bahasoan, Ida Baharuddin
openaire +1 more source
Pengaruh Komitmen Pegawai dan Kepuasan Kerja terhadap Disiplin Kerja di Kantor Badan Penelitian dan Pengembangan Provinsi Riau [PDF]
, 2014 The aims of this research is to find out the employee commitment and job satisfaction with work discipline. The population of this research is taken from employes of Research and Development of Riau Province Offices.
Hasbi, M. I. (Muhammad) +1 more
core
Pengaruh Motivasi dan Disiplin Serta Lingkungan Kerja terhadap Kinerja Pegawai Sekretariat Daerah Kabupaten Ogan Komering Ilir [PDF]
, 2012 The purpose of this research is to know the influence of motivation, discipline, and workeEnvironment not only jointly but also partially of employee performance for Secretariat of Ogan Komering Ilir Area. This research used 63 employees for the samples.
Atmawijaya, G. (Ganda)
core +2 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Pengaruh Individu dan Organisasi terhadap Disiplin Kerja (Studi pada PT. Bank “X” Cabang “Y” Malang) [PDF]
, 2010 Work discipline is the condition desired by organization. Work discipline will never be happened automatically, but should be shaped by many factors, both individual and organizational factors.
Habsyi, T. A. (Taher) +2 more
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
IJEBD (International Journal of Entrepreneurship and Business Development)Design/methodology/approach: This type of research uses a quantitative approach and uses primary data. The population in the study was 110 employees of the Cirebon Regency Secretariat. The sampling technique in this research uses saturated samples,
Hikmah Nur Janah +2 more
doaj +1 more source
PENGARUH GAYA KEPEMIMPINAN, DISIPLIN KERJA, DAN KOMPENSASI TERHADAP KINERJA KARYAWAN (Studi Kasus Pada Toko Bang Ahmad Kab. Jombang) [PDF]
This study aims to: (1) Understand Employee Performance, Leadership Style, Work Discipline, and Compensation at Ahmad's store. (2) Understand the direct influence of Leadership Style on Employee Performance.
Attamyizu, Muhammad Zamzam
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source