Results 81 to 90 of about 426,342 (280)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

PENGARUH KEPRIBADIAN KARYAWAN DAN PERSEPSI BUDAYA ORGANISASI TERHADAP EMPLOYEE ENGAGEMENT PADA PT. INDUSTRI TELEKOMUNIKASI INDONESIA (PERSERO) [PDF]

, 2016
Penelitian dilatarbelakangi oleh hasil penjualan yang menurun dan tidak memenuhi target, denda keterlambatan penyelesaian proyek yang tinggi, dan kerugian yang dialami PT. INTI (Persero) pada tahun 2014.
Nurjanah, Rian
core  

Linking Distributive and Procedural Justice to Employee Engagement Through Social Exchange: A Field Study in India [PDF]

, 2013
Research linking justice perceptions to employee outcomes has referred to social exchange as its central theoretical premise. We tested a conceptual model linking distributive and procedural justice to employee engagement through social exchange ...
Aarti Ramaswami, Adams J.S., Ang S., Aroian L.A., Arup Varma, Aselage J., Atkouf O., Avolio B.J., Bentler P.M., Bentler P.M., Bhatnagar J., Bies R.J., Biswas S., Biswas S., Blau P., Bowen D.E., Boxall P., Brockner J., Browne M.W., Browne M.W., Budhwar P., Budhwar P., Budhwar P., Byrne Z.S., Cohen-Charash Y., Colquitt J.A., Colquitt J.A., Colquitt J.A., Colquitt J.A., Colquitt J.A., Coyle-Shapiro J.A.M., Cropanzano R., Cropanzano R., Cropanzano R., Eisenberger R., Eisenberger R., Fiske S.T., Folger R., Goodman L.A., Greenberg J., Greenberg J., Hofstede G., Hu L.T., Iacobucci D., James L.R., James L.R., Kashyap V., Kenny D.A., Konovsky M.A., Kuvaas B., Loi R., MacKinnon D.P., MacKinnon D.P., Masterson S.S., McBain R., Moorman R.H., Moorman R.H., Ngo H.Y., Niehoff B.P., Pillai R., Podsakoff P.M., Raja U., Rhoades L., Rhoades L., Rousseau D.M., Rupp D.E., Saks A.M., Schaufeli W.B., Settoon R.P., Sobel M.E., Soumendu Biswas, Sparrow P.R., Tekleab A.G., Thibaut J., Tsui A.S., Wood R.E., Yadapadithaya P.S.   +76 more
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Corporate social responsibility, corporate reputation and employee engagement [PDF]

Corporate social responsibility (CSR) has been outlined as voluntarily additional legal duties of organization to serve environment and community. This voluntarily actions of corporate help them to develop reputation which can shape favorable attitude of
Ali, Imran, Ali, Jawaria Fatima
core   +1 more source

Current challenges that New Zealand small: Medium sized enterprises face in retention of employees: With a focus on the landscape industry [PDF]

, 2018
Employee retention is a growing concern in Human Resources. Poor employee retention results in businesses incurring increased expenses. Businesses have to search for, recruit and retain employees when job vacancies occur.
Taylor, Beverly, Williams, Devon
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

PENGARUH MOTIVASI KERJA DAN BUDAYA ORGANISASI TERHADAP EMPLOYEE ENGAGEMENT KARYAWAN KANTOR PUSAT PT. PERKEBUNAN NUSANTARA VIII BANDUNG [PDF]

, 2018
ABSTRAK Sumber daya manusia adalah sumber daya penggerak yang berpengaruh terhadap sumber daya lainnya dan proses operasional perusahaan. Sumber daya manusia yang memiliki keterikatan tinggi pada Kantor Pusat PT.
Pembimbing I, Dr. Ina Ratnamiasih., SE., MSi, Tsania Sam Eva, 134010230   +1 more
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source