Results 101 to 110 of about 19,080,997 (296)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

The Impact of Employee Well-being on Employee Retention

open access: yes, 2019
This paper aims to examine the impact of employee well-being on employee retention. A total sample of 238 employees was taken from Syrian Private Financial Institutions located in Damascus. The research concluded that there is a significant positive impact of workplace well-being and psychological well-being on employee retention.
Warrak, Ahmad, Ismail, Hassan
openaire   +1 more source

Working for wellness: defining, measuring, and enhancing employee well-being

open access: yes, 2017
The focus of this thesis was on the utility of the workplace in promoting employee well-being. The thesis applied principles of positive psychology (PP) to the field of occupational health psychology (OHP).
Page, Kathryn May (3634438)
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Homeostasis and Well Being [PDF]

open access: yes
The paper suggests that maintenance of a homeostatic equilibrium provides a rationale for many actions of economic agents. Homeostatic equilibrium has physical, economic, emotional, psychological and environmental dimensions.
John Malcolm Dowling, Yap Chin Fang
core   +2 more sources

2017 Well Being Trust Annual Report

open access: yes, 2018
Tyler Norris, writing in the 2017 Well Being Trust Annual Report: This is a promising moment for our nation, as the importance of mental health and well-being become obvious to growing numbers of Americans and awareness of mental health disorders ...
Well Being Trust
core   +1 more source

Perspectives and Practices of Healthcare Leaders in Supporting Healthcare Worker Well-Being: A Reality Check

open access: yesJournal of Healthcare Leadership
Iris M Reijmerink,1 Maarten J van der Laan,1 Fedde Scheele,2,3 J K Götz Wietasch4 1Department of Surgery, University Medical Centre Groningen, Groningen, the Netherlands; 2Amsterdam Academic Medical Center, Research in Education, Amsterdam, the ...
Reijmerink IM   +3 more
doaj  

Research on the impact of remote work on employee productivity and well–being

open access: yesУченые записки Российской академии предпринимательства
The study is devoted to the analysis of the impact of remote work on the productivity and well–being of employees. The article examines the results of research from different parts of the world, showing how the remote format affects labor efficiency, the
L. Y. Martynovskiy
doaj   +1 more source

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