Results 81 to 90 of about 19,080,997 (296)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

High involvement management and employee well-being [PDF]

IZA World of Labor, 2015
A wide range of high involvement management practices, such as self-managed teams, incentive pay schemes, and employer-provided training have been shown to boost firms’ productivity and financial performance. However, less is known about whether these practices, which give employees more discretion and autonomy, also benefit employees. Recent empirical
openaire   +4 more sources

WORKING CONDITIONS AND EMPLOYEE WELL-BEING: AN EMPIRICAL ANALYSIS [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie
The study examines the relationship between working conditions and employee well-being, based on the premise that the work experience is multidimensional and includes both organizational resources and stress factors.
BACAINȚAN NARCIS PARIS
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Workplace Disability Diversity and Job-Related Well-Being in Britain: A WERS2004 Based Analysis [PDF]

This paper attempts to establish empirically whether there is a link between workplace disability and employee job-related well-being. Using nationally representative linked employer-employee data for Britain, I employ alternative econometric techniques ...
Haile, Getinet Astatike
core  

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Hybrid HRM systems and employee well-being: a self-determination theory perspective

Purpose Drawing from the human resource management (HRM) literature and framed with self-determination theory, this article seeks to investigate the impact of a hybrid system of HRM, characterized by the integration of practices from high-involvement ...
Cafferkey, Kenneth, Liu, Li, Townsend, Keith, She, Long   +3 more
core   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Does Digitization Lead to Sustainable Economic Behavior? Investigating the Roles of Employee Well-Being and Learning Orientation

As digital transformation accelerates across industries, understanding its role in shaping sustainable employee behavior is essential, particularly in mission-driven sectors like healthcare. This study investigates how digitization influences sustainable
Ahmad Bassam Alzubi, Ibrahim Alkish, Hasan Yousef Aljuhmani, Kolawole Iyiola   +3 more
core   +1 more source

Well-being and being-well

, 2018
This chapter provides a framework by drawing upon the work of Maurice Merleau-Ponty in order to conceptualize health as a mind-body-world phenomenon.
Bullington, Jennifer,, Jennifer Bullington   +1 more
core   +1 more source