Results 71 to 80 of about 19,080,997 (296)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Well-being

, 2023
Mean personal well-being index (PWI) and national well-being index (NWI) scores for Statistical Area 2 (2018) units. Original data sourced from Census 2018 and New Zealand Attitudes and Values Study 2018.
Jesse Wiki (11444635)
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Enhancing Employee Well-Being Through Scene Innovation in Retail Enterprises: A Case Study on the Chinese Enterprise Pang Donglai

In retail enterprises, employee well-being is recognized as a key factor influencing service quality and operational sustainability. While prior research has extensively investigated enterprise-centric approaches to improving employee well-being, little ...
Shiyu Liang, Chaoyue Meng, Niannian Cheng, Xinwei Pei   +3 more
core   +1 more source

Exploring the effects of employee and organisational characteristics on two models of employee well-being within an organisational health research framework [PDF]

, 2008
[Abstract]Research within clinical, organisational and community contexts, generally equates an individual’s sense of well-being with the absence of adverse psychological states.
Burns, Richard A.
core  

Review of the Well-Being Agenda in Small Island States: Challenges to Measuring Tourism Employee Well-Being

Island Studies Journal
A holistic agenda for sustainable human development of tourism is lacking in Small Island States (SIS). The main goal of this research is to provide an integrative framework for measuring employee well-being in tourism-dependent SIS.
Miguel Puig-Cabrera, Apisalome Movono, Regina Scheyvens   +2 more
doaj   +1 more source

Examining the Impact of Emotional Intelligence on Employee Well-Being and Employee Engagement in the Digital Era

Journal of Karnali Academy of Health Sciences, 2023
Introduction: Employee Well-Being (EWB) and Employee Engagement (EE) are crucial for a healthy workplace, but concern about Well-Being (WB) and EE are still prevalent.
Pramila Pudasaini Thapa, Hari Rana, Özge Ucar, Josana Khanal, Kapil Amgain   +4 more
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Does the Organization–Employee Relationship Matter? Linking the Organization–Employee Relationship With Employee Well-Being and Performance

Economic and Business Review
The study examines the relationship between the organization–employee relationship (OER), well-being, and work performance of remote workers who were mandated to work from home because of the uncertainties and health risks brought about by the COVID-19 ...
Deepti Pathak, Gaurav Joshi
doaj   +1 more source