Results 111 to 120 of about 314,024 (302)

Virtues of SIN - effects of an immigrant workplace introduction program [PDF]

We evaluate an immigrant workplace introduction program aimed at helping individuals considered employable but at the same time expected to experience substantial difficulties in finding work.
Åslund, Olof, Johansson, Per
core  

Supported Employment in Britain

, 1997
This paper describes supported employment, its growth as an alternative to traditional day services and research which indicates potentially beneficial outcomes in the areas of increased employee income, social integration, satisfaction, engagement in ...
Stephen Beyer, Mark Kilsby
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Implementing the Place-Train Approach in Train-Place Services: Organizational Culture and Supported Employment

Nordic Journal of Working Life Studies
Supported employment (SE) is increasingly implemented in employment services worldwide. The disruptive character of SE, involving a shift from ‘train-place’ to ‘place-train’ models of vocational rehabilitation, has led to growing recognition of ...
Blanka Støren-Vaczy, Vidar Bakkeli
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Estimating the Effect of Training on Employment and Unemployment Durations: Evidence From Experimental Data [PDF]

Using data from a social experiment, we estimate the impact of training on the duration of employment and unemployment spells for AFDC recipients. Although an experimental design eliminates the need to construct a comparison group for this analysis ...
John C. Ham, Robert J. LaLonde
core  

Supported employment in the region of Litoměřice [PDF]

, 2007
This thesis is aimed at the policy of employment of disabled people and at supported employment in the region of Litoměřice. The basic question of the theoretical part is what contemporary policy of empolyment of disabled people in the Czech Republic is (
Galiová, Hana
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The Entrepreneurial Model of Supported Employment

, 1992
Existing supported employment models have provided vocational education and job placement opportunities for special education students. These models of supported employment have limited utility in rural settings due to low population density, great ...
Joe Ferrara, Robert Markve, Randall Morris, Eric Rudrud   +3 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source