Results 121 to 130 of about 1,600,881 (309)

A qualitative study of the IPS employment specialist role in the context of Nav employment in Norway

open access: yesBMC Psychiatry
Background Employment is recognised as a fundamental human right. Still, many people experiencing severe mental illness are outside the workforce. Appropriate employment has several benefits for mental health and is central to recovery and citizenship ...
Cathrine Moe   +8 more
doaj   +1 more source

Reducing gender inequalities to create a sustainable care system [PDF]

open access: yes, 2008
Women mainly provide family care, but as women’s economic opportunities increase they will not continue to bear the costs of providing care unaided. To create a sustainable care system, care and carers must be better supported and more highly valued to ...
Himmelweit, Susan, Land, Hilary
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Supported Employment

open access: yesSwiss Medical Forum ‒ Schweizerisches Medizin-Forum, 2011
U Hepp, B Dubs, U Bigler
  +4 more sources

The Effects of Minimum Wages on Employment: Theory and Evidence from the US [PDF]

open access: yes
Recent work on the economic effects of minimum wages has stressed that the standard economic model, where increases in minimum wages depress employment, is not supported by the empirical findings in some labour markets.
Alan Manning   +2 more
core  

More Color More Pride: Addressing Structural Barriers to Interracial LGBTQ Loving [PDF]

open access: yes, 2019
Through an examination of State-supported racial structures, this Essay illustrates that even after the legalization of interracial and same-sex marriages, the State’s control over housing, education, and employment prospects impedes the formation of ...
Prasad, Praatika
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Supported Employement: Recommendations for successful implementation in South Africa

open access: yesSouth African Journal of Occupational Therapy, 2011
Introduction: This article reports on the findings of a descriptive qualitative study in which supported employment (SE), as a potential strategy to facilitate the employment of persons with disability in the open labour market in South Africa, was ...
Lana van Niekerk   +6 more
doaj  

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