Results 141 to 150 of about 314,024 (302)

Информационный бюллетень

open access: yes, 2015
Title from PDF caption (viewed on April 17, 2019)."Podderzhka pri trudoustroĭstve v malykh gruppakh | ėto uslugi i zani︠a︡tii︠a︡, v ramkakh kotorykh gruppa uchastnikov (menee 8 chelovek) rabotaet v kachestve komandy ili rabocheĭ gruppy."This archived ...

core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

The Development of Supported Employment in Scotland

open access: yes, 2006
Supported employment is consistently identified as an effective employment or practice model. Its economic, social and other benefits are well documented, although several studies show variable outcomes especially in terms of economic benefits.
Hunter, Susan, Ridley, Julie
core  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Handbook Supported Employment

open access: yes, 2007
[Excerpt] Supported employment has brought about improvements in the quality of life of women and men with a disability by enabling them to become active participants in society.
Kamp, Michael, Lynch, Christy
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Supported Employment: the employment consultants' perspective

open access: yes, 2011
Supported employment (SE) organisations work to support people with mental illness into employment. This study sought to examine the experiences and perspectives of staff that work for a SE service.
Kliem, Alexis
core   +1 more source

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