Results 141 to 150 of about 1,600,881 (309)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Disability employment policy [PDF]
This paper is the first in a series aimed at analyzing disability employment policy, and developing recommendations for policy reform in middle income countries.
Mont, Daniel
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Employment and the Social Economy. EU Funding Opportunities for Developing Human Resources [PDF]
, 2012 The paper examines the role of EU cohesion policy in the field of human resources development and improving conditions for employment. The main objective of the analysis is to present a comprehensive picture about funding opportunities in connection with
Kengyel, Ákos
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Mentoring Programmes as a successful instrument for career development of people with disabilities and disadvantaged [PDF]
, 2007 [Excerpt] For many years the Mentoring, as a form of support for young people without work experience, is well-known practice. In the past ten years the Mentoring has proved itself as a wide-applied method of support in the career of people with ...
Leonardo da Vinci Pilot Projects
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Reducing gender inequalities to create a sustainable care system
, 2011 Women mainly provide family care, but as women’s economic opportunities increase they will not continue to bear the costs of providing care unaided. To create a sustainable care system, care and carers must be better supported and more highly valued to ...
Himmelweit, Susan, Land, Hilary
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Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Who writes the pay slip? Do R&D subsidies merely increase researcher wages?. [PDF]
Government intervention in private R&D activity is common practice nowadays. However, its impact may not be unambiguously positive. First, companies may simply replace private R&D budgets with the public R&D grant.
Aerts, Kris
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