Results 71 to 80 of about 10,463,905 (347)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Self-Employment and the Transformation of Employment Relationships in Europe [PDF]
, 2018 Europe is currently witnessing a rise in the heterogeneity and multiplicity of models for utilising the productive capacity of the population. This applies both to formal salaried employment (subcontracting, temporary work, part-time work, casual work and zero-hour contracts, etc.) and its combination in various shapes and forms with different types of
openaire +3 more sources
Innovation and the Growth of Service Firms: The Polish Case [PDF]
, 2013 Differences in the growth of firms remain a major topic in economics and strategy research. In this paper we investigated the link between innovation performance and employment growth.
Grabowski, Wojciech +2 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Labor Market Frictions, Job Insecurity and the Flexibility of the Employment Relationship [PDF]
We analyze a search model of the labor market in which firms and workers meet bilaterally and negotiate over wages in the presence of private information.
Fred Robert-Nicoud (University of Geneva) +2 more
core +3 more sources
Flexible employment relationships and careers in times of the COVID-19 pandemic
Journal of Vocational Behavior, 2020 The COVID-19 pandemic represents a crisis that affects several aspects of people's lives around the globe. Most of the affected countries took several measures, like lockdowns, business shutdowns, hygiene regulations, social distancing, school and ...
Daniel Spurk, C. Straub
semanticscholar +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Does parental employment affect children's educational attainment? [PDF]
, 2008 This paper analyzes whether there exists a causal relationship between parental employment and children's educational attainment. We address potential endogeneity problems due to (i) selection of parents in the labor market by estimating a model on ...
Hörisch, Hannah
core +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The Impact of New Firm Formation on Regional Development in the Netherlands [PDF]
This paper examines the relationship between new firm formation and regional employment change in the Netherlands. Using a new regional data base for the period 1988-2002, we examine the time lags involved in the relationship. We also investigate whether
André van Stel, Kashifa Suddle
core +3 more sources