Results 81 to 90 of about 366,025 (373)

Epithelial–Mesenchymal Transition (EMT)

International Journal of Molecular Sciences, 2023
Epithelial–mesenchymal transition (EMT) is a cellular process involved in many physiological and pathological conditions [...]
Guidalberto Manfioletti, Monica Fedele
openaire   +4 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Mapping lung cancer epithelial-mesenchymal transition states and trajectories with single-cell resolution. [PDF]

, 2019
Elucidating the spectrum of epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET) states in clinical samples promises insights on cancer progression and drug resistance.
Anchang, Benedict, Bendall, Sean C, Benson, Jalen A, Ignatiadis, Nikolaos, Karacosta, Loukia G, Kimmey, Samuel C, Plevritis, Sylvia K, Shrager, Joseph B, Tibshirani, Robert   +8 more
core  

Capsaicin triggers autophagic cell survival which drives epithelial mesenchymal transition and chemoresistance in bladder cancer cells in an Hedgehog-dependent manner [PDF]

, 2016
Bladder cancer (BC) is a common urologic tumor characterized by high risk of recurrence and mortality. Capsaicin (CPS), used as an intravesical drug for overactive bladder, was demonstrated to induce cell death in different cancer cells including BC ...
Amantini, C, CARDINALI, CLAUDIO, GISMONDI, Angela, MORELLI, MARIA BEATRICE, Nabissi, M, Santoni, G., Santoni, M   +6 more
core   +1 more source

Association of the Epithelial–Mesenchymal Transition (EMT) with Cisplatin Resistance

International Journal of Molecular Sciences, 2020
Therapy resistance is a characteristic of cancer cells that significantly reduces the effectiveness of drugs. Despite the popularity of cisplatin (CP) as a chemotherapeutic agent, which is widely used in the treatment of various types of cancer ...
M. Ashrafizadeh, A. Zarrabi, K. Hushmandi, M. Kalantari, R. Mohammadinejad, Tahereh Javaheri, G. Sethi   +6 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

UrBAN: Urban Beehive Acoustics and PheNotyping Dataset

Scientific Data
In this paper, we present a multimodal dataset obtained from a honey bee colony in Montréal, Quebec, Canada, spanning the years of 2021 to 2022. This apiary comprised 10 beehives, with microphones recording more than 3000 hours of high quality raw audio,
Mahsa Abdollahi, Yi Zhu, Heitor R. Guimarães, Nico Coallier, Ségolène Maucourt, Pierre Giovenazzo, Tiago H. Falk   +6 more
doaj   +1 more source

Single-pixel terahertz imaging: a review

Opto-Electronic Advances, 2020
This paper is devoted to reviewing the results achieved so far in the application of the single-pixel imaging technique to terahertz (THz) systems. The use of THz radiation for imaging purposes has been largely explored in the last twenty years, due to ...
Zanotto Luca, Piccoli Riccardo, Dong Junliang, Morandotti Roberto, Razzari Luca   +4 more
doaj   +1 more source

Three-Dimensional Pinecone-like Binder-Free Pt–TiO₂ Nanorods on Ti Mesh Structures: Synthesis, Characterization and Electroactivity towards Ethanol Oxidation

Molecules, 2022
We report here the synthesis of binderless and template-less three-dimensional (3D) pinecone-shaped Pt/TiO2/Ti mesh structure. The TiO2 hydrothermally synthesized onto Ti mesh is composed of a mixture of flower-like nanorods and vertically aligned bar ...
Naser Mohammadi, Juan Carlos Abrego-Martinez, Mohamed Mohamedi   +2 more
doaj   +1 more source