Results 81 to 90 of about 338,860 (400)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Genetic algorithm-enhanced microcomb state generation

Communications Physics
Microcavities enable the generation of highly efficient microcombs, which find applications in various domains, such as high-precision metrology, sensing, and telecommunications.
Celine Mazoukh, Luigi Di Lauro, Imtiaz Alamgir, Bennet Fischer, Nicolas Perron, A. Aadhi, Armaghan Eshaghi, Brent E. Little, Sai T. Chu, David J. Moss, Roberto Morandotti   +10 more
doaj   +1 more source

Spectrally resolved wave-mixing between near- and far-infrared pulses in gas

New Journal of Physics, 2013
We investigate the nonlinear wave-mixing in gases between intense, short optical pulses and long-wavelength fields (mid infrared and terahertz). We show numerically that the beating between the sum- and difference-frequency generation components can be ...
M Clerici, D Faccio, L Caspani, M Peccianti, O Yaakobi, B E Schmidt, M Shalaby, F Vidal, F Légaré, T Ozaki, R Morandotti   +10 more
doaj   +1 more source

A General Initialization Scheme for Electromagnetic Transient Simulation: Towards Large-Scale Hybrid AC-DC Grids [PDF]

arXiv, 2020
With the large-scale hybrid AC-DC grids coming into being, electromagnetic transient (EMT) simulation is required to accurately describe the dynamics of systems. However, the EMT steady-state initialization for hybrid AC-DC system is difficult and time-consuming when the system scale is huge.
arxiv  

TGFβ impairs HNF1α functional activity in Epithelial-to-Mesenchymal Transition interfering with the recruitment of CBP/p300 acetyltransferases [PDF]

, 2019
The cytokine transforming growth factor β (TGFβ) plays a crucial role in the induction of both epithelial-to-mesenchymal transition (EMT) program and fibro-cirrhotic process in the liver, where it contributes also to organ inflammation following several ...
Amicone, Laura, Battistelli, Cecilia, Bisceglia, Francesca, Marchetti, Alessandra, Montaldo, Claudia, Noce, Valeria, Strippoli, Raffaele, Tripodi, Marco, Zammataro, Agatino   +8 more
core   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Robust Distributed Collaborative Beamforming for Wireless Sensor Networks with Channel Estimation Impairments

Sensors, 2019
We propose a new collaborative beamforming (CB) solution robust (i.e., RCB) against major channel estimation impairments over dual-hop transmissions through a wireless sensor network (WSN) of K nodes. The source first sends its signal to the WSN.
Oussama Ben Smida, Slim Zaidi, Sofiène Affes, Shahrokh Valaee   +3 more
doaj   +1 more source

Effective-Medium Theory with No Approximation for One Dimensional Metamaterials [PDF]

arXiv, 2021
Transfer matrix theory (TMT) is used to study the effective-medium theory (EMT) of one dimensional metamaterials (1D MMs). 1D MMs with equal diagonal elements of periodic transfer matrix are defined as 1D perfect MMs (1D PMMs), which can be suitable for EMT with no approximation.
arxiv  

The Extended Mind Thesis and Mechanistic Explanations [PDF]

, 2013
The Extended Mind Thesis (EMT) is traditionally formulated against the bedrock of functionalism, and ongoing debates are typically bogged down with questions concerning the exact relationship between EMT and different versions of functionalism.
Fazekas, Péter
core  

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source