Nature Communications, 2016 Determining results of asymmetric reactions can take long periods of time and consume large amounts of organic solvents during work-up and analysis. Here, the authors report a bifunctional organic probe that can bind to chiral hydroxyacids, and provide ...
Keith W. Bentley +2 more
doaj +1 more source
A Racemic Naphthyl-Coumarin-Based Probe for Quantitative Enantiomeric Excess Analysis of Amino Acids and Enantioselective Sensing of Amines and Amino Alcohols. [PDF]
ChemistryOpen, 2022 Li JY +8 more
europepmc +1 more source
Chemistry – A European Journal, EarlyView.One‐pot transition‐metal‐free methods for the synthesis of all three bonds of the alkyne's triple bond are reviewed. After analysis of several named reactions and discussion of improvements, recent advances in the synthesis of alkynes are discussed. Each section contains a proposed reaction mechanism and analysis of the strengths and weaknesses of the ...
Eugene Kim +4 more
wiley +1 more source
Fluorine-containing substituents: metabolism of the α,α-difluoroethyl thioether motif
Beilstein Journal of Organic Chemistry, 2019 We report the metabolism of the recently introduced α,α-difluoroethyl thioether motif to explore further its potential as a substituent for bioactives discovery chemistry. Incubation of two aryl–SCF2CH3 ethers with the model yeast organism Cunninghamella
Andrea Rodil +4 more
doaj +1 more source
Determination of the Enantiomeric Excess of Horner Phosphines by 13C NMR Spectroscopy. A 13C and 31P NMR Study of the Diastereomeric Complexes Formed with [η3-(+)(1R,5R )-Pinenyl]nickel Bromide Dimer [PDF]
, 1986 Richard Mynott +2 more
openalex +1 more source
Silent Partners in the Mill: Unveiling the Role of Additives in Mechanochemical Synthesis
Chemistry – A European Journal, EarlyView.Mechanochemistry offers a sustainable, solvent‐free alternative to traditional synthesis, often enhanced by additives in a process known as additive‐assisted grinding. This review discusses how various additives, including liquids, ionic solids, and advanced materials like ionic liquids and piezoelectric compounds, improve reaction efficiency ...
Johanna Breinsperger +3 more
wiley +1 more source
Helvetica Chimica Acta, EarlyView.Four stereogenic centers are formed diastereoselectively in one step from a cyclic (E,E)‐1,5‐diene system using an electrophilic addition reaction. Subsequent ozonolytic cleavage of the intact Z‐double bond, followed by intramolecular nucleophilic substitution, yields an octahydroterfurandione with a threo,cis,threo configuration, an arrangement found ...
Holger Schimanski +6 more
wiley +1 more source
High-throughput screening of α-chiral-primary amines to determine yield and enantiomeric excess. [PDF]
Tetrahedron, 2021 Moor SR +3 more
europepmc +1 more source
Molecular imprinting for neurology: Materials, applications, and limitations
Ibrain, EarlyView.Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma +3 more
wiley +1 more source
DIOS‐MSEED: A chip‐based method for measurement of enantiomeric excess by kinetic resolution/mass spectrometry [PDF]
, 2001 Zhouxin Shen +4 more
openalex +1 more source