Results 51 to 60 of about 667,303 (272)

Towards Chemoenzymatic Syntheses of Both Enantiomers of Phosphoemeriamine

Molecules
An enzyme-promoted addition of nitromethane to the appropriate phosphorylated imine (aza-Henry reaction) intended to be used in the synthesis of the title phosphoemeriamine, a phospha-analog of emeriamine (aminocarnitine), failed due to the ...
Piotr Kiełbasiński, Małgorzata Kwiatkowska, Piotr Łyżwa, Marian Mikołajczyk   +3 more
doaj   +1 more source

Harnessing Non‐Covalent Protein–Protein Interaction Domains for Production of Biocatalytic Materials Systems

Advanced Functional Materials, EarlyView.
Non‐covalent protein–protein interactions mediated by SH3, PDZ, or GBD domains enable the self‐assembly of stable and biocatalytically active hydrogel materials. These soft materials can be processed into monodisperse foams that, once dried, exhibit enhanced mechanical stability and activity and are easily integrated into microstructured flow ...
Julian S. Hertel, Maria Alessandra Martini, Marius Stoeckle, Annika J. Weber, Kersten S. Rabe, Christof M. Niemeyer   +5 more
wiley   +1 more source

Assignment-free chirality detection in unknown samples via microwave three-wave mixing

Communications Chemistry, 2022
Identification of chiral molecules in multi-component mixtures of unknown compositions remains a challenge. Here, the authors show that microwave three-wave mixing that uses broad-spectrum fields can detect chiral molecules in enantiomeric excess without
Greta Koumarianou, Irene Wang, Lincoln Satterthwaite, David Patterson   +3 more
doaj   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

(Poly)Borylated Species as Modern Reactive Groups toward Unusual Synthetic Applications

Angewandte Chemie, EarlyView.
In this review, we spotlight recent breakthroughs in α‐polyboron‐substituted carbon‐centered intermediates (carbanion, carbocation, radical, and carbene) and polyborylated alkenes. By bridging fundamental reactivity with the application potential of these extraordinary species, we hope this review will serve as a roadmap for harnessing these unique ...
Nadim Eghbarieh, Nicole Hanania, Pinaki Nad, Tipu Alam, Tamir Kish, Ahmad Masarwa   +5 more
wiley   +2 more sources

Enantioselective Growth of Chiral Serine‐Induced β‐Ag2Se Crystals from an Organoselenium Compound

Advanced Functional Materials, EarlyView.
Chiral amino acids direct the enantioselective crystallization of β‐Ag2Se nanocrystals from an organoselenium precursor. L‐ and D‐serine induce distinct morphologies and opposite homochiral adsorption preferences, transferring molecular handedness into the inorganic lattice.
Matan Oliel, Yarden B. Moshe, Gil Otis, Dana D. Medina, Yitzhak Mastai, Subhomoy Das   +5 more
wiley   +1 more source

Asymmetric Hydride Shift Reactions Catalyzed by Chiral Aluminium Complexes

Angewandte Chemie, EarlyView.
An asymmetric intramolecular hydride shift reaction has been developed that is catalyzed by Al Lewis acids in conjunction with a chiral BINOL‐derived ligand. Racemic THP substrates are transformed into cyclohexene products via an intermediate prochiral enone; which undergoes a key 1,5‐hydride shift reaction.
Mostafa M. Amer, Jingyan Hou, Jinfang Wang, Akvile Mazeikaite, Timothy J. Donohoe   +4 more
wiley   +2 more sources

Chiroptical activity of hydroxycarboxylic acids with implications for the origin of biological homochirality

Communications Chemistry, 2021
Enantiomerically-enriched hydroxycarboxylic acids have been found in meteorites, but the possible origin of this asymmetry has not been explored experimentally.
Jana Bocková, Nykola C. Jones, Uwe J. Meierhenrich, Søren V. Hoffmann, Cornelia Meinert   +4 more
doaj   +1 more source

Rapid Determination of Enantiomeric Excess via NMR Spectroscopy: A Research-Informed Experiment

, 2017
An undergraduate chemistry experiment that draws from primary research is described. The experiment exploits chiral supramolecular assemblies for the determination of enantiomeric excess by 1H NMR spectroscopy.
J. Fossey, E. Anslyn, William D. G. Brittain, S. Bull, Brette M. Chapin, C. S. L. Duff, T. James, G. Lees, Stephanie Lim, J. A. Lloyd, Charles V. Manville, D. Payne, Kimberley A Roper   +12 more
semanticscholar   +1 more source

Chiral Nanohoops as an Efficient Spin Polarization System

Advanced Functional Materials, EarlyView.
Chiral conjugated nanohoops with a central dibenzopentalene unit exhibit 90% spin polarization at low voltage and high conductivity. These properties make them ideal components in molecular spintronics applications. Abstract A central challenge in molecular spintronics is to achieve a high spin polarization at low operating voltages and ambient ...
Anu Gupta, Philipp Seitz, Mathias Hermann, Birgit Esser, Ron Naaman   +4 more
wiley   +1 more source