Results 61 to 70 of about 667,303 (272)
Angewandte Chemie, EarlyView.Various substituted chromane‐2‐carboxamides were successfully deracemized by employing a chiral benzophenone (BP, 10 mol%) as photocatalyst and an achiral thiol as additive (20 mol%). The method was applied to the concise enantioselective synthesis of five active pharmaceutical ingredients.
Biki Ghosh +5 more
wiley +2 more sources
Advanced Healthcare Materials, EarlyView.Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang +7 more
wiley +1 more source
Angewandte Chemie, EarlyView.We have developed stable, robust, and reusable heterogeneous metal catalysts for an efficient continuous flow asymmetric hydrogenation (AH) of a variety of olefins, far beyond the typical benchmark AH. The products are produced continuously over long periods of time with high catalytic performance (up to 99% ee).
Jorge Faiges +5 more
wiley +2 more sources
Life, 2013 A series of non-proteinogenic amino acids, most of them found quite commonly in the meteorites known as carbonaceous chondrites, were subjected to solid state radiolysis in vacuum to a total radiation dose of 3.2 MGy corresponding to 23% of the total ...
Yaser Hafez +3 more
doaj +1 more source
Redox-enabled direct stereoconvergent heteroarylation of simple alcohols
Nature Communications, 2021 Synthesizing complex structures of high enantiomeric excess from racemic feedstock is an enduring challenge. Here, the authors couple racemic secondary alcohols with pyrroles to form enantioenriched 2-substituted heteroarenes, via a borrowing hydrogen ...
Yongbing Liu +4 more
doaj +1 more source
Estimation of Enantiomeric Excess Based on Rapid Host–Guest Exchange
Chemosensors, 2021 Chiral molecules possess enantiomers that have non-superimposable chemical structures but exhibit identical nuclear magnetic resonance (NMR) spectra.
Jan Labuta +7 more
doaj +1 more source
Emerging methods for the rapid determination of enantiomeric excess [PDF]
Chirality, 2002 AbstractMethods for enantiomeric excess determination using a variety of spectroscopic techniques are summarized. Particular attention is paid to techniques that have promise for application to problems of combinatorial catalyst discovery but have not yet been so employed. Chirality 14:534–540, 2002. © 2002 Wiley‐Liss, Inc.
openaire +2 more sources
Advanced Photonics Research, EarlyView.Recent advances in nanophotonics‐based chiral biosensing approaches are comprehensively reviewed, highlighting key trends, advantages, and limitations of each technology. Special attention is given to emerging strategies that exploit magneto‐optical and quantum plasmonic phenomena to enhance sensitivity down to the level of a few molecules, or even a ...
Jorge Ricardo Mejía‐Salazar
wiley +1 more source
Dual Circularly Polarized Luminescence from Chiral Boron‐Embedded Polycyclic Aromatic Hydrocarbons
Angewandte Chemie, EarlyView.Boron‐embedded polycyclic aromatic hydrocarbons featuring an asymmetric boron center coordinated by a proximal P═O group were synthesized. Anthracene‐fused boracyclic derivatives show dual circularly polarized luminescence (CPL) arising from excited‐state P═O⋯B dissociation, which converts point chirality into C−B axial chirality.
Tatsuya Mori +6 more
wiley +2 more sources
Novel Chiral Switching Ligands for Enantioselective Asymmetric Reductions of Prochiral Ketones
Molecules, 2001 The newly developed chiral ligands 1 and 4 show opposite enantioselectivity in the asymmetric reduction of prochiral ketones resulting in the production of either enantiomer depending on the metal complex with high enantiomeric excess.
S. Velmathi +3 more
doaj +1 more source