Results 61 to 70 of about 33,103 (197)

Determining enantiomeric excess using indicator-displacement assays

, 2008
The invention includes an enantioselective indicator-displacement assay useful to determine enantiomeric excess (ee) enantiomeric samples calorimetrically. Determination may be by inspection of color with the naked eye, spectrographic measurement, or mathematical calculation. Concentration may also be determined.
Eric V. Anslyn, Lei Zhu, Jan Frantz Folmer-Andersen   +2 more
openaire   +3 more sources

Asymmetric amplification in amino acid sublimation involving racemic compound to conglomerate conversion [PDF]

, 2011
A straightforward unprecedented sublimation protocol that reveals both conversion of a racemic compound into a racemic conglomerate and subsequent enantioenrichment has been developed for the proteinogenic amino acid valine.
Cintas, Pedro, Noorduin, Wim L., Ortiz Menéndez, José Eugenio, Torres Pérez-Hidalgo, Trinidad José, Viedma, Cristobal   +4 more
core   +4 more sources

Stochastic Approach to Enantiomeric Excess Amplification and Chiral Symmetry Breaking

, 2006
Stochastic aspects of chemical reaction models related to the Soai reactions as well as to the homochirality in life are studied analytically and numerically by the use of the master equation and random walk model. For systems with a recycling process, a
Blackmond D. G., Buhse T., Calvin M., Frank F. C., Goldanskii V. I., Gridnev I. D., Gridnev I. D., Islas J. R., Japp F. R., Lente G., Lente G., Mills M. H., Pasteur L., Pearson K., Press W. H., Saito Y., Saito Y., Saito Y., Saito Y., Saito Y., Sato I., Sato I., Shibata R., Singleton D. A., Singleton D. A., Soai K., Soai K., Soai K., Stryer L., Vollhardt K. P. C.   +29 more
core   +1 more source

Spatial dynamics of homochiralization [PDF]

, 2005
The emergence and spreading of chirality on the early Earth is considered by studying a set of reaction-diffusion equations based on a polymerization model.
Brandenburg, Axel, Multamaki, Tuomas
core   +2 more sources

Determination of Enantiomeric Excess in Amine Derivatives with Molecular Self‐Assemblies [PDF]

Angewandte Chemie, 2015
AbstractWe report the first fluorescence‐based assay for the rapid determination of the ee value of amines, amino alcohols, and amino acid esters. The method uses the self‐assembly of 2‐formylphenylboronic acid with a chiral diol and a chiral amine or derivatives (of unknown chirality) to produce two diastereomeric iminoboronates that differ in their ...
Shcherbakova, Elena G., Minami, Tsuyoshi, Brega, Valentina, James, Tony D., Anzenbacher, Pavel   +4 more
openaire   +2 more sources

Enantioselective desymmetrization of cyclohexadienones via an intramolecular Rauhut–Currier reaction of allenoates

Nature Communications, 2016
The Rauhut-Currier reaction is a powerful method to form carbon-carbon bonds. Here, the authors report an enantioselective intramolecular variant between alkenes and allenoates, giving access to highly functionalised bicyclic lactones in excellent ...
Weijun Yao, Xiaowei Dou, Shan Wen, Ji’en Wu, Jagadese J. Vittal, Yixin Lu   +5 more
doaj   +1 more source

Hydroformylation of Vinylferrocene with Rhodium and Platinum Catalysts

CHIMIA, 1986
2- and 3-ferrocenylpropionaldehydes (2 and 3) have been prepared by highly regioselective hydroformylation of vinylferrocene (1) using rhodium and platinum catalysts.
László Kollár, Barbara Floris, Piero Pino   +2 more
doaj   +1 more source

Visualization of enantiorecognition by excited-state conformation modulation

Nature Communications
Chiral purity is crucial in life sciences, emphasizing the importance of precise enantiomeric identification and the development of analytical techniques.
Zizhao Huang, Ying Hu, Jie Sun, Zhenyi He, Tao Jiang, He Tian, Xiang Ma   +6 more
doaj   +1 more source

Calcium(II)-mediated resolution of methyl o-chloromandelate with chiral O,O′-dibenzoyltartaric acid in preparative scale

Main Group Metal Chemistry, 2019
We report here the coordination-mediated resolution of methyl o-chloromandelate, which is a key intermediate for clopidogrel, in preparative scale. The reaction of CaO, optically pure (2R, 3R)-O,O′-dibenzoyltartaric acid, and methyl o-chloromandelate in ...
Xu Hong-Wu, Wu Li-Huan, Ren Qiang, Liu Cui-Yu, Yan Guan-Qing   +4 more
doaj   +1 more source

CALB Immobilized onto Magnetic Nanoparticles for Efficient Kinetic Resolution of Racemic Secondary Alcohols: Long-Term Stability and Reusability

Molecules, 2019
In this study, an immobilization strategy for magnetic cross-linking enzyme aggregates of lipase B from Candida antarctica (CALB) was developed and investigated. Magnetic particles were prepared by conventional co-precipitation.
Xiu Xing, Jun-Qi Jia, Jing-Fan Zhang, Zi-Wen Zhou, Jun Li, Na Wang, Xiao-Qi Yu   +6 more
doaj   +1 more source