Results 161 to 170 of about 86,276 (266)

Enantiomers of oxyphenonium bromide. Analytical and pharmacological aspects.

open access: yesPharmaceutisch weekblad. Scientific edition, 1987
This thesis focuses on some analytical and pharmacological aspects of enantiomers. Enantiomers always exist as a pair of non-identical mirror-images that resemble each other as a left and a rigbt hand. The configuration around the central (carbon) atom is opposite.
openaire   +3 more sources

Trends in toxicological findings and drug seizures of MDMA in New Zealand from 2010 to 2022

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract 3,4‐Methylenedioxymethamphetamine (MDMA) or “ecstasy,” is a commonly used drug worldwide, including in New Zealand, where 4.8% of the population aged 15 years or over reported using it in a 2023/2024 survey. This study provides additional insights on MDMA prevalence data in New Zealand by reporting toxicology data from Coronial and driving ...
Thomas J. Sheehan   +4 more
wiley   +1 more source

Computational redesign and directed evolution of a lanthanide-dependent photoredox enzyme for enantioselective diol cleavage. [PDF]

open access: yesChem Sci
Leiss-Maier F   +7 more
europepmc   +1 more source

In vitro and in vivo metabolism profiles of cathinone and pseudoephedrine: Discrimination between khat and pseudoephedrine uses

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract In the present study, the metabolism of khat (Catha edulis) and pseudoephedrine was compared with the aim of identifying objective criteria that could be used to discriminate between them for forensic and doping‐control purposes. An in vitro study using human liver microsomes and an in vivo study using rat urine were performed under harmonized
Jong Suk Park   +6 more
wiley   +1 more source

Rapid enantioselective fluorescence recognition and chiral separation of free amino acids. [PDF]

open access: yesNat Commun
Li Y   +8 more
europepmc   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

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