Enantiomers of oxyphenonium bromide. Analytical and pharmacological aspects.
This thesis focuses on some analytical and pharmacological aspects of enantiomers. Enantiomers always exist as a pair of non-identical mirror-images that resemble each other as a left and a rigbt hand. The configuration around the central (carbon) atom is opposite.
openaire +3 more sources
Enantioselective Determination of Amphetamine-Type Stimulants in Environmental Waters Using SPE and CE-MS/MS. [PDF]
Clivillé-Cabré P +3 more
europepmc +1 more source
Trends in toxicological findings and drug seizures of MDMA in New Zealand from 2010 to 2022
Abstract 3,4‐Methylenedioxymethamphetamine (MDMA) or “ecstasy,” is a commonly used drug worldwide, including in New Zealand, where 4.8% of the population aged 15 years or over reported using it in a 2023/2024 survey. This study provides additional insights on MDMA prevalence data in New Zealand by reporting toxicology data from Coronial and driving ...
Thomas J. Sheehan +4 more
wiley +1 more source
Computational redesign and directed evolution of a lanthanide-dependent photoredox enzyme for enantioselective diol cleavage. [PDF]
Leiss-Maier F +7 more
europepmc +1 more source
Abstract In the present study, the metabolism of khat (Catha edulis) and pseudoephedrine was compared with the aim of identifying objective criteria that could be used to discriminate between them for forensic and doping‐control purposes. An in vitro study using human liver microsomes and an in vivo study using rat urine were performed under harmonized
Jong Suk Park +6 more
wiley +1 more source
Rapid enantioselective fluorescence recognition and chiral separation of free amino acids. [PDF]
Li Y +8 more
europepmc +1 more source
Psychedelics, entactogens and psychoplastogens for depression and related disorders
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley +1 more source
DFT calculations and theory do not support enantiospecificity in NMR J-coupling constants. [PDF]
Perras FA, Zwanziger JW, Rossini AJ.
europepmc +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source

