Results 231 to 240 of about 3,273,294 (390)

Charge Relocation Enables a Modular and Diastereoselective Synthesis of cis‐Substituted Tetrahydrofurans

Angewandte Chemie International Edition, Accepted Article.
Diastereoselective construction of organic scaffolds from simple and commercial materials is a powerful strategy in contemporary organic synthesis. Herein, we report a novel disconnection for the direct preparation of tetrahydrofurans (THF) and corresponding derivatives from acyl chlorides and alkenes using charge relocation. Newly synthesised Hantzsch
Zhi-Jie Niu, Bogdan R. Brutiu, Margaux Riomet, Daniel Kaiser, Nuno Maulide   +4 more
wiley   +1 more source

Enantioselective Synthesis of Spirocyclic Isoxazolones Using a Conia-Ene Type Reaction. [PDF]

J Org Chem
Kamlar M, Putatunda S, Císařová I, Veselý J.   +3 more
europepmc   +1 more source

Enantioselective Synthesis of α-Aryl Ketones by a Cobalt-Catalyzed Semipinacol Rearrangement. [PDF]

Angew Chem Int Ed Engl
Kalomenopoulos PG, Emayavaramban B, Johnston CP.   +2 more
europepmc   +1 more source

β‐Quaternary α‐Amino Acids via Iridium‐Catalyzed Branched and Enantioselective Hydroalkylation of 1,1‐Disubstituted Styrenes

Angewandte Chemie International Edition, Accepted Article.
A cationic Ir(I)‐complex modified with the chiral diphosphine DM‐SEGPHOS mediates the hydroalkylation of diverse α‐methyl styrenes with N‐aryl glycine derivatives. The processes occur with complete branched selectivity and high enantioselectivity. Styrenes possessing higher α‐alkyl substituents also participate to provide the targets with moderate to ...
Fenglin Hong, L. Anders Hammarback, Yihong Wang, Craig M. Robertson, John Bower   +4 more
wiley   +1 more source

Enantioselective Synthesis of Fluorinated Indolizidinone Derivatives. [PDF]

Org Lett, 2023
Escolano M, Gaviña D, Díaz-Oltra S, Sánchez-Roselló M, Del Pozo C.   +4 more
europepmc   +1 more source

Enantioselective synthesis of goniobutenolides A and B

, 1995
Soo Y. Ko, Joanne Lerpiniere
openalex   +1 more source

Influence of Ligand Design and Non‐Covalent Interactions on the Isoselective Ring‐Opening Polymerization of rac‐β‐Butyrolactone Using Salan and Salalen Rare‐Earth Metal Catalysts

Angewandte Chemie International Edition, EarlyView.
Polyhydroxybutyrates are key sustainable polyesters, but controlling the stereoregularity is crucial for exhibiting the most promising thermal and mechanical properties. Highly active rare‐earth metal salan/salalen complexes yield isotactic (Pm up to 0.96 at 0 °C) or syndioenriched (Pr up to 0.91) PHB, depending on the steric demand of the ligand and ...
Stefanie Hörl, Ion Chiorescu, Jonas Bruckmoser, Jonas Futter, Bernhard Rieger   +4 more
wiley   +1 more source

Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering

Chemistry – A European Journal, Volume 28, Issue 67, December 1, 2022., 2022
Structural and biochemical data demonstrate that 4‐phenylbenzoic acid binds within the active site of the cytochrome P450 monooxygenase CYP199A4, but no oxidation occurs. Protein engineering and molecular dynamic simulations establish that aromatic oxidation is enabled by a subtle shift of the substrate relative to the heme, thus improving our ...
Tom Coleman, Joel Z. H. Lee, Alicia M. Kirk, Daniel Z. Doherty, Matthew N. Podgorski, Dilshi K. Pinidiya, John B. Bruning, James J. De Voss, Elizabeth H. Krenske, Stephen G. Bell   +9 more
wiley   +1 more source

Towards Substrate–Reagent Interaction of Lochmann–Schlosser Bases in THF: Bridging THF Hides Potential Reaction Site of a Chiral Superbase

Chemistry – A European Journal, Volume 28, Issue 69, December 9, 2022., 2022
The isolation of a new THF‐solvated, ferrocene‐based Lochmann–Schlosser base with all four components lithium, potassium, carbanion, and alkoxide led to the observation of new structural motifs with respect to these superbasic reagents. The “kick out” of a THF leads to the detachment, providing the typical Li/K reaction site, whereas the “smart pass ...
Lukas Brieger, Tobias Schrimpf, Rebecca Scheel, Christian Unkelbach, Carsten Strohmann   +4 more
wiley   +1 more source

Synthesis of New Chiral Catalysts, Isoquinuclidinylmethanols, for the Enantioselective Addition of Diethylzinc to Aryl Aldehydes

, 1997
Hiroshi Hongo, Hiroto Nakano, Kazuto Iwasa   +2 more
openalex   +1 more source