Results 211 to 220 of about 2,677,083 (277)

Enantioselective Synthesis of Complex Carbocycles by C-H Insertion of Aryl/Aryl Carbenes. [PDF]

open access: yesACS Catal
Ruiz JM   +11 more
europepmc   +1 more source

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 41, 5 October 2026.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon   +9 more
wiley   +1 more source

Enantioselective Synthesis of 3-Alkyl-1,5-Functionalized 1,4-Diynes via Isoxazol-5(4<i>H</i>)-ones. [PDF]

open access: yesOrg Lett
Torán R   +6 more
europepmc   +1 more source

Engineering Metal‐Pocket Cooperativity in Single‐Atom COF Nanozymes for Selective Cascade Catalysis

open access: yesAdvanced Materials, Volume 38, Issue 58, 16 October 2026.
A multilevel programming strategy is developed to engineer single‐atom COF nanozymes with tunable metal centers and chiral pockets inspired by heme–pocket cooperativity. This approach enables controlled metal–pocket interplay for asymmetric cascade catalysis, delivering high activity, selectivity, and recyclability in an asymmetric oxidation–aldol ...
Ziping Li   +7 more
wiley   +1 more source

Clinopodium nepeta Essential Oil and Its Major Constituents Pulegone and Menthone: Composition and Activity Against Verticillium dahliae, Phytophthora infestans, and Macrophomina phaseolina

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Chemical fractionation of Clinopodium nepeta essential oil reveals pulegone and menthone as markedly more potent antifungal isolates than the whole oil, with activity varying among pathogens. Pulegone exhibits superior efficacy against Verticillium dahliae and Phytophthora infestans, whereas menthone shows enhanced activity against Macrophomina ...
Mohamed Taibi   +11 more
wiley   +1 more source

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