Results 91 to 100 of about 42,802 (288)

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

Machine learning-assisted amidase-catalytic enantioselectivity prediction and rational design of variants for improving enantioselectivity

Nature Communications
Biocatalysis is an attractive approach for the synthesis of chiral pharmaceuticals and fine chemicals, but assessing and/or improving the enantioselectivity of biocatalyst towards target substrates is often time and resource intensive.
Zi-Lin Li, Shuxin Pei, Ziying Chen, Teng-Yu Huang, Xu-Dong Wang, Lin Shen, Xuebo Chen, Qi-Qiang Wang, De-Xian Wang, Yu-Fei Ao   +9 more
doaj   +1 more source

A Comparative Study of C₂-Symmetric and C₁-Symmetric Hydroxamic Acids in Vanadium-Catalyzed Asymmetric Epoxidation of Allylic Alcohols

Molecules
Hydroxamic acids are emerging as versatile chiral ligands for metal-catalyzed asymmetric oxidations due to their tunable electronic and steric environments.
Marco Valtierra-Galván, Alfredo Rodríguez-Hernández, Israel Bonilla-Landa, Felipe Barrera-Méndez, Francisco Javier Enríquez-Medrano, Ramón Enrique Díaz de León-Gómez, José Luis Olivares-Romero   +6 more
doaj   +1 more source

Catalytic enantioselective synthesis of quaternary carbon stereocentres. [PDF]

, 2014
Quaternary carbon stereocentres-carbon atoms to which four distinct carbon substituents are attached-are common features of molecules found in nature. However, before recent advances in chemical catalysis, there were few methods of constructing single ...
Overman, Larry E, Quasdorf, Kyle W
core  

Shedding Light on Synthetic Autocatalysis: From Conventional Closed‐Shell Chemistries to Overlooked Open‐Shell Occurrences

Chemistry – A European Journal, EarlyView.
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley   +1 more source

Evaluation of the Impact of Flutriafol on Soil Culturable Microorganisms and on Soil Enzymes Activity

Agriculture
Fungicides play a role in managing plant diseases but raise concerns about environmental impact, emphasizing the need to understand and minimize their effects on non-target ecosystems. Flutriafol is a fungicide used to combat fungal diseases in crops. It
Diana-Larisa Roman, Mariana Adina Matica, Bianca-Vanesa Boros, Constantina-Bianca Vulpe, Adriana Isvoran   +4 more
doaj   +1 more source

Inter- and intramolecular enantioselective carbolithiation reactions

Beilstein Journal of Organic Chemistry, 2013
In this review we summarize recent developments in inter- and intramolecular enantioselective carbolithiation reactions carried out in the presence of a chiral ligand for lithium, such as (−)-sparteine, to promote facial selection on a C=C bond.
Asier Gómez-SanJuan, Nuria Sotomayor, Esther Lete   +2 more
doaj   +1 more source

Stereodivergent, Diels-Alder-initiated organocascades employing α,β-unsaturated acylammonium salts: scope, mechanism, and application. [PDF]

, 2017
Chiral α,β-unsaturated acylammonium salts are novel dienophiles enabling enantioselective Diels-Alder-lactonization (DAL) organocascades leading to cis- and trans-fused, bicyclic γ- and δ-lactones from readily prepared dienes, commodity acid chlorides ...
Abbasov, Mikail E, Hudson, Brandi M, Romo, Daniel, Tantillo, Dean J   +3 more
core   +2 more sources

Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview

Chemistry – A European Journal, EarlyView.
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati, Claudio Trapella, Vinicio Zanirato, Virginia Cristofori, Anna Fantinati   +4 more
wiley   +1 more source

The supramolecular attitude of metal-salophen and metal-salen complexes [PDF]

, 2018
In this review we cover some aspects of metal-salophen and metal-salen complex chemistry related to their supramolecular attitude. We examined under the lens of the non-covalent interactions their potential to behave as building blocks for auto-assembled
Dalla Cort, Antonella, Leoni, Luca
core   +2 more sources