Results 111 to 120 of about 42,802 (288)

Combining pot, atom and step economy (PASE) in organic synthesis. Synthesis of tetrahydropyran-4-ones [PDF]

, 2007
The combination of pot, atom and step economy (PASE) in the synthesis of organic molecules of medium complexity can lead to a significant 'greening' of a synthetic route.
Clarke, Paul A., Martin, William H. C., Santos, Soraia   +2 more
core   +1 more source

Iridium‐Catalyzed Linear‐Selective sp3 C−H Alkylation of N‐Methylamides Using Alkenes Enabled by Diphosphite Ligands

Chemistry – A European Journal, EarlyView.
An iridium‐catalyzed linear‐selective sp3 C─H alkylation of N‐methylamides with alkenes is described. This method tolerates various N‐methylacetamide derivatives and has a broad alkene scope. Mechanistic studies were also conducted. Internal alkenes can also be used through in situ consecutive alkene isomerization.
Haluhi Takahashi, Takanori Shibata
wiley   +1 more source

Chirality‐Induced Hydroxyapatite Manipulates Enantioselective Bone‐Implant Interactions Toward Ameliorative Osteoporotic Osseointegration

Advanced Science
Inspired by the fundamental attribute of chirality in nature, chiral‐engineered biomaterials now represent a groundbreaking frontier in biomedical fields.
Liang Yang, Jinzhou Du, Shengyang Jin, Shuyi Yang, Zhaowei Chen, Shiyang Yu, Cunyi Fan, Chao Zhou, Hongjiang Ruan   +8 more
doaj   +1 more source

Enantioselective Evans-Tishchenko Reduction of b-Hydroxyketone Catalyzed by Lithium Binaphtholate

Molecules, 2011
Lithium diphenylbinaphtholate catalyzed the enantioselective Evans-Tishchenko reduction of achiral b-hydroxyketones to afford monoacyl-protected 1,3-diols with high stereoselectivities.
Makoto Nakajima, Tomonori Ichibakase, Masato Nakatsu   +2 more
doaj   +1 more source

A General Strategy for the Synthesis of Jerangolids Enabled by π‐allyl Stille Coupling

Chemistry – A European Journal, EarlyView.
A general strategy for the synthesis of jerangolids is established, featuring a late‐stage π‐allyl Stille coupling of two advanced, highly customizable building blocks to form the skipped diene core. The approach provides access to all naturally occurring jerangolids, including jerangolid H, whose configuration is confirmed by NMR analysis.
Janick Schug, Bernd Morgenstern, Johann Jauch   +2 more
wiley   +1 more source

Optimization of the asymmetric synthesis of (S)-1-phenylethanol using Ispir bean as whole-cell biocatalyst

Green Processing and Synthesis, 2019
In this study, enantiomerically pure (S)-1-phenylethanol was produced via asymmetric bioreduction of acetophenone. Ispir bean (Phaseolus vulgaris) was used as an alcohol dehydrogenase (ADH) source since whole cells are cheaper than isolated enzymes ...
Atak Gunay Baydar, Bayraktar Emine, Mehmetoglu Ülkü   +2 more
doaj   +1 more source

Chiral Thioxanthones as Modulators of P-glycoprotein: Synthesis and Enantioselectivity Studies

Molecules, 2018
Recently, thioxanthone derivatives were found to protect cells against toxic P-glycoprotein (P-gp) substrates, acting as potent inducers/activators of this efflux pump.
Ana Lopes, Eva Martins, Renata Silva, Madalena M. M. Pinto, Fernando Remião, Emília Sousa, Carla Fernandes   +6 more
doaj   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

Chemistry – A European Journal, EarlyView.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis, Kyriakos D. Nikopoulos, Ioannis N. Lykakis   +2 more
wiley   +1 more source

Enantioconvergent catalysis

Beilstein Journal of Organic Chemistry, 2016
An enantioconvergent catalytic process has the potential to convert a racemic starting material to a single highly enantioenriched product with a maximum yield of 100%.
Justin T. Mohr, Jared T. Moore, Brian M. Stoltz   +2 more
doaj   +1 more source

The Asymmetric Self‐Replicative Alkylation of N‐Arylaldimines Using Organolithium Reagents

Chemistry – A European Journal, EarlyView.
Here, we report a new asymmetric autoinductive reaction; the addition of nBuLi to N‐arylaldimines to form chiral lithium amides. The reaction proceeds with full conversion and complete transfer of chirality, representing the first example of an asymmetric autoinductive reaction with organolithium reagents.
Anka Hagelschuer, Paco Visser, Ben L. Feringa   +2 more
wiley   +1 more source