Results 131 to 140 of about 12,531 (256)

Organocatalytic asymmetric synthesis of atropisomeric tetraarylethenes: design, properties, and applications. [PDF]

Chem Sci
An M, Lu CJ, Xie F, Sun YJ, Sun Z, Xi LL, Liu RR.   +6 more
europepmc   +1 more source

Enhanced Biocatalysis in Nanofluidic Membrane Reactors With Goldilocks Nanopores for Enzymes

Small, EarlyView.
We show that enzyme confinement within the three‐dimensionally interconnected nanochannels of a polyurea molecular network membrane, featuring pore‐size tunability to match the enzyme size, enables a highly active nanofluidic reactor platform. Stable continuous‐flow operation for >200 h and a 30 000‐fold increase in specific space‐time yield over ...
Wangsuk Oh, Ji‐Woong Park
wiley   +1 more source

Rhodium-catalyzed atroposelective C-H fluoroallylation of heteroarenes with <i>gem</i>-difluorocyclopropanes. [PDF]

Chem Sci
Li J, Wang F, He X, Huang G, Rong ZQ, Li X.   +5 more
europepmc   +1 more source

Contactless Detection of Giant Helicity‐Dependent Photovoltage in Chiral 2D Perovskites

Small, EarlyView.
A novel contactless probe—circularly polarized time‐resolved surface photovoltage spectroscopy is demonstrated to evaluate helicity‐dependent charge separation dynamics without the need for electrical contacts. Application of this novel methodology to chiral 2D perovskites reveals giant transient surface photovoltage anisotropy.
Joanna Dehnel, Ido Zemer, Rawan Hirzalla, Ido Hadar, Igal Levine   +4 more
wiley   +1 more source

Enantioselective Pyrazole Alkylation via Iridium and Squaramide Catalyzed N-H Insertion. [PDF]

J Am Chem Soc
Ruud KJ, Antonucci AJ, Lukovic V, Vennemeyer A, Dong VM.   +4 more
europepmc   +1 more source

Molecularly Engineered 2D Xene Heterostructures With Implanted Peroxidase‐Like Activity for Mimicking Enzyme Functions

Small Methods, EarlyView.
A modular electropolymerization strategy is used to covalently graft a vinyl‐terminated Co(II) molecular catalyst onto allyl 2D germanane. This molecular programming approach yields a 2D Xene nanozyme with implanted peroxidase‐like activity, enabling sensitive and selective electrochemical detection of hydrogen peroxide and the monitoring of ...
Yiming Lei, Xavier Sala, Jordi García‐Antón, Jose Muñoz   +3 more
wiley   +1 more source

Stereoselective, borane-catalysed synthesis of <i>syn</i>-β-hydroxyketones from α,β-unsaturated ketones. [PDF]

Chem Sci
Macleod J, Nimmo AJ, Cockcroft JHP, Dominguez-Molano P, Nichol GS, Thomas SP.   +5 more
europepmc   +1 more source

Complex Chemistry of a Chiral Terpyridine Ligand Based on (1R)‐(+)‐Camphor

Zeitschrift für anorganische und allgemeine Chemie, EarlyView.
From (1R)‐(+)‐camphor, a chiral terpyridine ligand is accessible in a few steps that coordinates to divalent metal ions of the first and second transition metal row. From structural characterization, the steric repulsion of the two equatorial methyl groups of the tetrahydromethanoquinoline units becomes evident, which causes cyclometalation of the ...
Julia Ehrhard, Marc H. Prosenc, Werner R. Thiel   +2 more
wiley   +1 more source

A Bifunctional Aminoxyl-Bipyridine Peptide Catalyst for the Atroposelective Copper-Catalyzed Aerobic Oxidation of Biaryl Diols. [PDF]

J Am Chem Soc
Marvich HM, Langner OC, Tampellini N, Miller SJ.   +3 more
europepmc   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source