Results 71 to 80 of about 42,802 (288)

Oligomerization of optically active N-(4-hydroxyphenyl)mandelamide in the presence of β-cyclodextrin and the minor role of chirality

Beilstein Journal of Organic Chemistry, 2014
The oxidative oligomerization of a chiral mandelamide derivative (N-(4-hydroxyphenyl)mandelamide, 1) was performed in the presence of horseradish peroxidase, laccase and N,N'-bis(salicylidene)ethylenediamine-iron(II) to obtain chiral oligophenols 2.
Helmut Ritter, Antonia Stöhr, Philippe Favresse   +2 more
doaj   +1 more source

Comparative Analysis of the Conversion of Mandelonitrile and 2-Phenylpropionitrile by a Large Set of Variants Generated from a Nitrilase Originating from Pseudomonas fluorescens EBC191

Molecules, 2019
The arylacetonitrilase from the bacterium Pseudomonas fluorescens EBC191 has been intensively studied as a model to understand the molecular basis for the substrate-, reaction-, and enantioselectivity of nitrilases.
Andreas Stolz, Erik Eppinger, Olga Sosedov, Christoph Kiziak   +3 more
doaj   +1 more source

Enantioselective Organocatalytic Diels-Alder Trapping of Photochemically Generated Hydroxy-o-Quinodimethanes [PDF]

, 2016
The photoenolization/Diels-Alder strategy offers straightforward access to synthetically valuable benzannulated carbocyclic products. This historical light-triggered process has never before succumbed to efforts to develop an enantioselective catalytic ...
Cuadros, Sara, Dell'Amico, Luca, Melchiorre, Paolo, Vega Pe\uf1aloza, Alberto   +3 more
core   +2 more sources

Enantioselective Palladium‐Catalyzed Transformations

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Tietze, Lutz F., Ila, Hiriyakkanavar, Bell, Hubertus P.   +2 more
openaire   +3 more sources

Chiral Derivatives of Xanthones: Investigation of the Effect of Enantioselectivity on Inhibition of Cyclooxygenases (COX-1 and COX-2) and Binding Interaction with Human Serum Albumin

Pharmaceuticals, 2017
Searching of new enantiomerically pure chiral derivatives of xanthones (CDXs) with potential pharmacological properties, particularly those with anti-inflammatory activity, has remained an area of interest of our group.
Carla Fernandes, Andreia Palmeira, Inês I. Ramos, Carlos Carneiro, Carlos Afonso, Maria Elizabeth Tiritan, Honorina Cidade, Paula C.A.G. Pinto, M. Lúcia M.F.S. Saraiva, Salette Reis, Madalena M.M. Pinto   +10 more
doaj   +1 more source

Enantioselective PCCP Brønsted acid-catalyzed aza-Piancatelli rearrangement. [PDF]

, 2019
An enantioselective aza-Piancatelli rearrangement has been developed using a chiral Brønsted acid based on pentacarboxycyclopentadiene (PCCP). This reaction provides rapid access to valuable chiral 4-amino-2-cyclopentenone building blocks from readily ...
Delgado, Jose M, Hammersley, Gabrielle R, Nichol, Meghan F, Read de Alaniz, Javier, Steffens, Helena C, Veits, Gesine K   +5 more
core  

Towards energetically viable asymmetric deprotonations : selectivity at more elevated temperatures with C2-symmetric magnesium bisamides [PDF]

, 2011
A novel chiral magnesium bisamide has enabled the development of effective asymmetric deprotonation protocols at substantially more elevated temperatures.
Aggarwal, Alexakis, Allan, Allan J. B. Watson, Anderson, Aoki, Aoki, Aoki, Aoki, Bassindale, Blümke, Brownbridge, Brownbridge, Bunn, Bunn, Bunn, Busch-Petersen, Carswell, Clegg, Conway, Corey, Cousins, Eaton, Eaton, Graf, Graf, Gronnow, Hama, Henderson, Henderson, Henderson, Henderson, Henderson, Hodgson, Ila, Kerr, Kerr, Kerr, Knochel, Leitner, Linsey S. Bennie, Melzig, Michael Middleditch, Mulvey, Navarro, Netherton, Sato, Shirai, Shirai, Simpkins, Simpkins, Westerhausen, William J. Kerr, Wunderlich, Çalimsiz   +54 more
core   +1 more source

Dynamic Kinetic Resolution of Hetero biaryl Ketones by Zinc- Catalyzed Asymmetr ic Hydrosil ylation [PDF]

, 2019
Adiastereo- and highly enantioselective dynamic kinetic resolution (DKR) of configurationally labile hetero- biaryl ketones is described. The DKR proceeds by zinc- catalyze dhydrosilylation of the carbonyl group ,thus leading to ...
Carmona, José A., Fernández Fernández, Rosario Fátima, Hornillos, Valentín, Iglesias Sigüenza, Francisco Javier, Lassaletta, José M., López Serrano, Joaquín, Ros Lao, Abel   +6 more
core   +1 more source

Photoenzymatic Hydroalkylation Enables Streamlined Access to Aryl Glutarimide Precursors. [PDF]

Angew Chem Int Ed Engl
We report a photoenzymatic hydroalkylation that enables streamlined, stereocontrolled access to aryl glutarimide precursors relevant to targeted protein degradation. Engineered flavin‐dependent “ene”‐reductases provide broad scope and high enantioselectivity through a distinct electron transfer–enantioselective proton transfer pathway.
Xu Z, Mukherjee P, Gossert S, Thomas S, Vasilev VH, Welin ER, Tan Y, McKenna SM, Emmanuel MA, Hyster TK.   +9 more
europepmc   +3 more sources

Molybdenum-catalyzed enantioselective sulfoxidation controlled by a nonclassical hydrogen bond between coordinated chiral imidazolium-based dicarboxylate and peroxido ligands [PDF]

, 2018
Chiral alkyl aryl sulfoxides were obtained by molybdenum-catalyzed oxidation of alkyl aryl sulfides with hydrogen peroxide as oxidant in mild conditions with high yields and moderate enantioselectivities.
Carrasco Carrasco, Carlos Jesús, Galindo del Pozo, Agustín, Montilla Ramos, Francisco Javier   +2 more
core