Results 181 to 190 of about 12,531 (256)

Unlocking Stereodefined Olefins by Z‐Selective Transition Metals‐catalyzed C−H Activations

ChemCatChem, Volume 18, Issue 15, 14 August 2026.
The synthesis of Z‐olefins is an important challenge in synthetic organic chemistry. Within this review, we report a comprehensive overview of transition metals‐catalyzed Z‐selective C–H activations of (hetero)arenes for the synthesis of stereodefined olefins.
Francesco Capranica, Silvia Cattani, Gianpiero Cera   +2 more
wiley   +1 more source

Enantioselective Rh/Cu-Catalyzed Addition of Terminal Alkynes to Allenes for the Synthesis of Chiral 1,4-Enynes. [PDF]

Org Lett
Daiger M, Kromer J, Kaplan S, Breit B.
europepmc   +1 more source

Structure‐Guided Engineering of a Ser192Ala Variant Enhances Bidirectional Catalysis in Amycolatopsis sulphurea L‐Alanine Dehydrogenase

ChemCatChem, Volume 18, Issue 15, 14 August 2026.
A rationally engineered Ser192Ala variant of Amycolatopsis sulphurea L‐alanine dehydrogenase (L‐AlaDH) exhibits ∼2‐fold higher catalytic efficiency in both reductive amination and oxidative deamination. Experimental characterization confirms maintained stability under tested conditions, highlighting its potential as an improved biocatalyst for ...
Tuba Okur Aksu, Fatih Aktaş, Onur Serçinoğlu, Barış Binay   +3 more
wiley   +1 more source

Enantioselective α,α-Chlorofluorination of Sulfoxonium Ylides. [PDF]

Org Lett
Furniel LG, Capellaro KC, Câmara VS, Hayashi M, Echemendía R, Pinto CB, Salata ABAM, Filho JAL, Hantao LW, Ellena J, Burtoloso ACB.   +10 more
europepmc   +1 more source

Green Chiral HPLC Method for Lumefantrine Analysis: Method Development, Greenness Assessment, and Computational Studies

Chirality, Volume 38, Issue 8, August 2026.
A green chiral HPLC method was developed and validated for the determination of lumefantrine enantiomers. The method employs ethanol as a mobile phase as a sustainable and efficient alternative to hexane. The chiral recognition mechanism and elution order of the enantiomers were investigated using electronic circular dichroism and molecular docking ...
Amanda Mohr, Gustavo Machado das Neves, Érika Segala, Vera Lucia Eifler‐Lima, Martin Steppe   +4 more
wiley   +1 more source

Highly enantioselective reduction of benzophenones by engineered Geotrichum candidum alcohol dehydrogenase. [PDF]

Appl Microbiol Biotechnol
Tang Z, Otárola Tejada GG, Koesoema AA, Matsuda T.   +3 more
europepmc   +1 more source

A Comparative Study of the Influence of Water and Temperature on the Racemization of Five‐ and Six‐Membered l‐Alanine‐Derived Imides

Chirality, Volume 38, Issue 8, August 2026.
Racemization of chiral imides in dimethylformamide is shown to increase with increasing water content and temperature. The six‐membered imide ring system is more stable than the five‐membered analogue, with slower racemization under identical conditions and an absence of competing side reactions.
Diksha U. Sawant, William Chant, Peter Halat, Ekaterina I. Izgorodina, David R. Turner   +4 more
wiley   +1 more source

Asymmetric hydrogenation of 3<i>H</i>-azepines <i>via</i> catalytic kinetic resolution: access to <i>anti</i>-disubstituted azepanes. [PDF]

Chem Sci
Bui L, Yildiz DB, Matesanz DG, Matador E, Sanchez R, Atodiresei I, Lonardi G, Leonori D.   +7 more
europepmc   +1 more source

Mass Spectrometry in Chiral Analysis and Synthesis

Chirality, Volume 38, Issue 8, August 2026.
Chiral molecules have the same mass, yet there are MS approaches that can distinguish chiral molecules. MS‐based chiral chemistry matters in fundamental physical experiments, industrial applications, and clinical analysis. ABSTRACT Mass spectrometry (MS) has a role to play in chiral chemistry, in part through methods based on microdroplets and non ...
Brison A. Shira, Mahdiyeh Shahi, R. Graham Cooks   +2 more
wiley   +1 more source

Engineering Enantiocomplementary Protoglobins for Stereoconvergent Construction of <i>N</i>-Alkylated α-Aminoketones. [PDF]

J Am Chem Soc
Qin ZY, Li ZQ, Zhang C, Heise JL, Mao R, Wu SJ, Houk KN, Goddard Iii WA, Arnold FH.   +8 more
europepmc   +1 more source