Results 171 to 180 of about 12,531 (256)

Biocatalytic Application of Goodfellowiella coeruleoviolacea Imine Reductase: Enantioselective Synthesis of Cyclic Secondary Amines in Deep Eutectic Solvent‐Based Media

Advanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.
A Goodfellowiella coeruleoviolacea Imine Reductase is here reported as a novel enzyme for biocatalytic application in chiral amine synthesis. Deep eutectic solvents have been used to increase substrate loadings, up to 150 mM, and boost enzymatic activity. Reaction scope and scale‐up procedure showcased the protocol applicability.
Federica De Nardi, Alessandro Marchetto, Nicoletta Schiavo, Francesca Spyrakis, Francesca Paradisi, Cristina Prandi   +5 more
wiley   +1 more source

Enantio- and Site-Selective Synthesis of α-Substituted Hydrazines, Pyrazolidines, and Tertiary Alcohols by Copper-Catalyzed Allylic C-N and C-O Bond Formation. [PDF]

J Am Chem Soc
Johnson BE, Hughes GM, Wheatley E, Meek SJ.   +3 more
europepmc   +1 more source

Synergistic Mechanism Between Ir–Phosphinito Catalyst and HFIP Enables Asymmetric Hydrogenation of Ketones Under Acidic Conditions

Advanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.
A cooperative mechanism between a phosphinito Ir complex and HFIP provides a low‐energy pathway for hydrogen activation. This allowed the development of a highly efficient catalytic system for the hydrogenation of ketones that operates under acidic conditions, enabling the reduction of substrates containing phenols and carboxylic acids with no added ...
Martí Sidro, Agustí Lledós, María Vicent‐Morales, Jordi Benet‐Buchholz, Giuseppe Sciortino, Antoni Riera, Xavier Verdaguer   +6 more
wiley   +1 more source

DFT Calculation-Assisted Virtual Screening to Refine Chiral Phosphoric Acid-Catalyzed Allylboration Enabling Organocatalytic Synthesis of Tetrafibricin C21-C40 Fragment. [PDF]

JACS Au
Umemiya S, Hirata T, Terada M.
europepmc   +1 more source

Chemoenzymatic Synthesis of Chiral Piperidines Using the Immobilized Transaminase ATA‐117 in Continuous Flow Reactors

Advanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.
A robust continuous flow chemoenzymatic process was developed for the stereoselective synthesis of cis‐(2R,6R)‐2,6‐disubstituted piperidines, including the natural alkaloid (–)‐pinidinone. The asymmetric transamination of α,β‐unsaturated ketones was catalyzed by immobilized ATA‐117, followed by spontaneous aza‐Michael cyclization, providing the desired
Sara Vicinanza, Ilaria Magrini Alunno, Stefania Patti, Morena Pirotta, Francesca Annunziata, Raffaella Gandolfi, Paola Conti, Chiara Borsari, Ivan Bassanini, Erica Elisa Ferrandi, Daniela Monti, Lucia Tamborini   +11 more
wiley   +1 more source

Transferable enantioselectivity models from sparse data. [PDF]

Nature
Gallarati S, Bucci EM, Doyle AG, Sigman MS.   +3 more
europepmc   +1 more source

The Oxidation Mechanisms of Saturated Fatty Acids: Formation of Hydroperoxide Isomers and Production of 2‐Alkanones and Lactones

Journal of the American Oil Chemists' Society, Volume 103, Issue 8, Page 945-955, August 2026.
ABSTRACT Saturated fatty acids (SFAs) are generally regarded simply as being resistant to oxidation compared with unsaturated fatty acids. However, it has long been reported that SFAs can undergo oxidation when heated at high temperatures, leading to the formation of unique degradation products such as 2‐alkanones and lactones.
Kanji Aoyagi, Shunji Kato, Kiyotaka Nakagawa   +2 more
wiley   +1 more source

Enantioselective Geminal Olefin Disulfonoxylation. [PDF]

J Org Chem
Silver R, Nirpal AK, Kelley SP, Sathyamoorthi S.   +3 more
europepmc   +1 more source

Quantum Phenomena in Molecular and Biological Systems: A Decoherence‐Based Decision Framework With Falsifiable Predictions and a Failure‐Mode Taxonomy

Advanced Physics Research, Volume 5, Issue 8, August 2026.
A physics‐grounded framework based on decoherence timescales (τ_dec vs τ_func), Markovian validity, and falsifiability criteria is applied across molecular systems to distinguish where quantum effects are necessary, marginal, or irrelevant. The analysis integrates quantum chemistry, biological quantum mechanisms, and quantum computing under a unified ...
Sarfaraz K. Niazi
wiley   +1 more source

Rhodium-Catalyzed Desymmetric Addition of Boronic Acids to Malononitriles. [PDF]

J Am Chem Soc
Zhang M, Zhang Q, Cao J, Wang JJ, Wang J, Huang Z.   +5 more
europepmc   +1 more source