Results 231 to 240 of about 32,089 (279)

Enantioselective Synthesis of Renieramide.

ChemInform, 2004
A highly chemo- and enantioselective PTC alkylation has been developed that allows rapid access to orthogonally protected (S,S)-isodityrosine. Utility of this material in the construction of isodityrosine-containing cyclic peptides is demonstrated by synthesis of the natural product renieramide.
Barry Lygo, Luke Humphreys
openaire   +1 more source

Enantioselective Desymmetrization of Diesters

The Journal of Organic Chemistry, 2014
The desymmetrization of prochiral diesters with a chiral phosphoric acid catalyst to produce highly enantioenriched lactones in excellent yield is reported. The process is easily scaled and accommodates a variety of substitution patterns, many of which result in the generation of an enantioenriched all-carbon quaternary center.
Jennifer, Wilent, Kimberly S, Petersen
openaire   +2 more sources

Enantioselective Synthesis of Xanthatin

Chemistry – A European Journal, 2014
Abstract The enantioselective synthesis of cytostatic and antibiotic xanthatin ( 1 a ) is reported. As a key intermediate, a bicyclic compound 2 was identified, which can be readily synthesized from methyl‐2‐furoic acid in diastereo ...
Andreas, Bergmann, Oliver, Reiser
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Enantioselective polyene cyclizations

Organic & Biomolecular Chemistry, 2016
A comprehensive review covering the field of enantioselective polyene cyclizations.
Chad N, Ungarean, Emma H, Southgate, David, Sarlah   +2 more
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Enantioselective Hydroxyvinylation with Lithioethenes.

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Jacques Maddaluno, Yi Yuan, Anne Harrison-Marchand   +2 more
openaire   +1 more source

Enantioselective Synthesis of (‐)‐Idiospermuline.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Larry E Overman, Emily A Peterson
openaire   +1 more source

Enantioselective Synthesis of Chromenes.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Christophe Hardouin, Lise Burgaud, Alain Valleix, Eric Doris   +3 more
openaire   +1 more source

Enantioselective Synthesis of Silanol

Journal of the American Chemical Society, 2008
An enantioselective nucleophilic substitution reaction of achiral dialkoxysilane has been developed. The reaction proceeds with efficient stereocontrol on the silicon chirality center to give the enantioenriched silyl ether, which can be converted to the silanol without loss of enantiopurity.
Kazunobu, Igawa, Junko, Takada, Tomohiro, Shimono, Katsuhiko, Tomooka   +3 more
openaire   +2 more sources

Enantioselective Synthesis of Silacyclopentanes

Angewandte Chemie, 2016
AbstractA variety of functionalized silacyclopentanes were synthesized by highly enantioselective β‐eliminations of silacyclopentene oxides followed by stereospecific transformations. The reaction mechanism of the β‐elimination was elucidated by DFT calculations.
Kazunobu Igawa, Daisuke Yoshihiro, Yusuke Abe, Katsuhiko Tomooka   +3 more
openaire   +2 more sources

An Enantioselective Synthesis of Voriconazole

The Journal of Organic Chemistry, 2013
A new seven-step sequence to access voriconazole, a clinically used antifungal agent, was developed. The initial catalytic asymmetric cyanosilylation is the key to constructing the consecutive tetra- and trisubstituted stereogenic centers. The fluoropyrimidine unit frequently triggered unexpected side reactions, but careful amendment of the reaction ...
Keiji, Tamura, Makoto, Furutachi, Naoya, Kumagai, Masakatsu, Shibasaki   +3 more
openaire   +2 more sources