Results 41 to 50 of about 264,177 (294)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Platform Approach to Protein Encapsulates with Controllable Surface Chemistry

Molecules, 2022
The encapsulation of proteins into core-shell structures is a widely utilised strategy for controlling protein stability, delivery and release. Despite the recognised utility of these microstructures, however, core-shell fabrication routes are often too ...
Nina Warner, Ilja Gasan Osojnik Črnivec, Vijay Kumar Rana, Menandro Cruz, Oren A. Scherman   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Use of poly vinyl alcohol (PVA) cryogelation for tissue engineering: composites, scaffold formation and cell encapsulation [PDF]

, 2009
PVA cryogelation is a physical hydrogel formation method, which yields cryogels with comparable mechanical properties to vascular tissue. However PVA cryogels are not suitable for cell attachment and proliferation alone.
Vrana, Nihal Engin
core   +2 more sources

Probing encapsulation-induced changes in 2D/3D perovskite heterostructures for perovskite solar cells [PDF]

EES Solar
Two-dimensional/three-dimensional (2D/3D) perovskite heterostructures have been extensively employed for effective interfacial defect passivation, enabling highly efficient perovskite solar cells (PSCs). At the same time, encapsulation plays a vital role
Xin Liu, Tai Wu, Jingwen Cao, Xiaoran Sun, Meng Zhang, Xiaojing Hao   +5 more
doaj   +1 more source

A Mini Review of S-Nitrosoglutathione Loaded Nano/Micro-Formulation Strategies

Nanomaterials, 2023
As a potential therapeutic agent, the clinical application of S-nitrosoglutathione (GSNO) is limited because of its instability. Therefore, different formulations have been developed to protect GSNO from degradation, delivery and the release of GSNO at a
Hui Ming, Kunpeng Zhang, Shengbo Ge, Yang Shi, Chunan Du, Xuqiang Guo, Libo Zhang   +6 more
doaj   +1 more source

Co-encapsulation of human serum albumin and superparamagnetic iron oxide in PLGA nanoparticles: Part II. Effect of process variables on protein model drug encapsulation efficiency. [PDF]

, 2014
This study investigates encapsulation efficiency of model drug, encapsulated by magnetic poly d,l-lactic-co-glycolic acid (PLGA) nanoparticles (NPs). This is the following part of our preceding paper, which is referred in this paper as Part I.
Kardos, Andrea F., Gyenis, János, Shubhra, Quazi T. H., Tóth, Judit, Feczkó, Tivadar, Dósa, György   +5 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Encapsulation of EGCG by Zein-Gum Arabic Complex Nanoparticles and In Vitro Simulated Digestion of Complex Nanoparticles

Foods, 2022
Epigallocatechin gallate (EGCG) has many excellent qualities such as its antitumor, antiradiation and anti-oxidation properties, but its application is limited because its oral bioavailability is low and stability is poor.
Jianchang Jin, Chengzhi Liu, Huafei Tong, Yulu Sun, Min Huang, Gerui Ren, Hujun Xie   +6 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source