Results 41 to 50 of about 254,809 (298)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Use of poly vinyl alcohol (PVA) cryogelation for tissue engineering: composites, scaffold formation and cell encapsulation [PDF]
, 2009 PVA cryogelation is a physical hydrogel formation method, which yields cryogels with comparable mechanical properties to vascular tissue. However PVA cryogels are not suitable for cell attachment and proliferation alone.
Vrana, Nihal Engin
core +2 more sources
Probing encapsulation-induced changes in 2D/3D perovskite heterostructures for perovskite solar cells [PDF]
EES SolarTwo-dimensional/three-dimensional (2D/3D) perovskite heterostructures have been extensively employed for effective interfacial defect passivation, enabling highly efficient perovskite solar cells (PSCs). At the same time, encapsulation plays a vital role
Xin Liu +5 more
doaj +1 more source
A Mini Review of S-Nitrosoglutathione Loaded Nano/Micro-Formulation Strategies
Nanomaterials, 2023 As a potential therapeutic agent, the clinical application of S-nitrosoglutathione (GSNO) is limited because of its instability. Therefore, different formulations have been developed to protect GSNO from degradation, delivery and the release of GSNO at a
Hui Ming +6 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Foods, 2022 Epigallocatechin gallate (EGCG) has many excellent qualities such as its antitumor, antiradiation and anti-oxidation properties, but its application is limited because its oral bioavailability is low and stability is poor.
Jianchang Jin +6 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
In Situ Encapsulation of Biologically Active Ingredients into Polymer Particles by Polymerization in Dispersed Media [PDF]
, 2022 The encapsulation of biologically active ingredients (e.g., peptides, proteins, enzymes, drugs) into polymer particles is extensively used for drug delivery purposes.
Julien, Nicolas, Maëlle, Lages
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Pharmaceutics, 2023 Colorectal cancer is one of the most diffused tumoral diseases. Since most medicaments employed for its treatment are debilitating, the use of naturally derived products, which can be effective against the mutated cells and, in addition, can reduce most ...
Stefano Russo +7 more
doaj +1 more source