Results 131 to 140 of about 49,920 (244)

Preventive effect of injections of vitamin D on the levels of Klotho in the brain tissue of female lewis rats with experimental autoimmune ensephalomyelitis

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2019
Introdution: The aim of this study was to investigate the effect of vitamin D supplementation on Klotho levels of the brain tissue. Methods: In this laboratory experimental study, 25 female Lewis rats, after 2 weeks adaptation to lab environmental, were ...
seyedeh fatemeh fatemi, zia fallah mohammadi, vahid Talebi, Sayed mojtaba Hosseini   +3 more
doaj  

Mitochondrial protein nitration primes neurodegeneration in experimental autoimmune encephalomyelitis

, 2006
The mechanisms of axonal and neuronal degeneration causing visual and neurologic disability in multiple sclerosis are poorly understood. Here we explored the contribution of mitochondria to neurodegeneration in the experimental autoimmune ...
Lewin, Alfred S, Hauswirth, William W, Guy, John, Sun, Liang, Qi, Xiaoping   +4 more
core   +1 more source

Enhancing Preclinical Rigor: Evaluating Robustness and Numerical Stability in a Chronic Pancreatitis Mouse Model

Annals of the New York Academy of Sciences, Volume 1560, Issue 1, June 2026.
In a modified cerulein‐induced chronic pancreatitis (CP) mouse model, key hallmarks of CP were robustly induced in male and female C57BL/6J (BL6) and BALB/c mice, whereas cytokine responses varied partly according to strain and sex. The RORγt inhibitor GSK805 reduced Il23r expression in the BL6 strain, significantly decreased collagen I deposition and ...
Annika Thämlitz, Muhammad Imran Khan, Benjamin Schulz, Lorenzo Pilch, Brigitte Vollmar, Dietmar Zechner   +5 more
wiley   +1 more source

B cell-specific METTL3 depletion exacerbates experimental autoimmune encephalomyelitis

Cellular and Molecular Life Sciences
N6-methyladenosine (m6A), the most prevalent RNA modification, plays a pivotal role in regulating mRNA metabolism and cellular processes such as immune responses.
Xuzhong Pei, Xiying Wang, Jie Ding, Haojun Yu, Chunran Xue, Chong Xie, Yi Chen, Xinyu Lin, Hong Yang, Yangtai Guan   +9 more
doaj   +1 more source

Molecular Clocks in Translational Roadmap for Circadian‐Based Therapeutics in Lung Diseases

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
High‐amplitude circadian oscillations maintain lung immune and epithelial homeostasis. Chronic inflammation dampens peripheral clock amplitude, driving chronodisruption, barrier dysfunction, and remodeling. Clock‐targeted therapies re‐entrain the lung circadian clock, restore rhythmic immune resolution, and promote functional lung repair.
Kingshuk Panda, Renu Khasa, Srinivasan Chinnapaiyan, Saurabh Aggarwal, Irfan Rahman, Hoshang Unwalla   +5 more
wiley   +1 more source

Interferon-¿ regulates oxidative stress during experimental autoimmune encephalomyelitis

, 2002
Neurobiology, experimental autoimmune encephalomyelitis IFN-d, multiple sclerosis, neurodegeneration, oxidative ...
Saez-Torres, I., Montalban, X., Espejo, C., Hidalgo, Juan, Penkowa, Milena, Garcia, A., Martinez-Caceres, E.M.   +6 more
core  

Orexin/hypocretinin in multiple sclerosis and experimental autoimmune encephalomyelitis

Neural Regeneration Research, 2020
Jean Pierre Pallais, Catherine M Kotz, Milos Stanojlovic   +2 more
doaj   +1 more source

The effect of regular interval training on histochemical symptoms and cytokine and neurotrophic levels of brain tissue of the Lewis rats in experimental model of multiple sclerosis

Fiyz̤, 2018
Background: Multiple sclerosis is an inflammatory and chronic disease of the central nervous system. Regarding the possible effects of exercise in preventing this disease, the aim of this study was to investigate the effect of 6 weeks of high intensity ...
Sayed Mojtaba Hosseini , Zia Fallahmohammadi , Vahid Talebi   +2 more
doaj  

Pertussis vaccine-induced experimental autoimmune encephalomyelitis in mice

Translational Neuroscience, 2014
Stojković Aleksandra, Maslovarić Irina, Kosanović Dejana, Vučetić Dušan   +3 more
doaj   +1 more source

??? and experimental autoimmune encephalomyelitis [PDF]

Inpharma Weekly, 1996
openaire   +1 more source