Results 191 to 200 of about 49,920 (244)

Costimulation loss enhances IL-2-driven Treg generation by PI3K-STAT3 inhibition in CNS autoimmunity. [PDF]

EMBO Mol Med
Nam KH, Kim GR, Kim YR, Kwon YN, Kim SM, Choi JM.   +5 more
europepmc   +1 more source

Early Reduction in Mitochondrial Membrane Potential in Synaptic Mitochondria Contribute to Synaptic Pathology in the EAE Mouse Model of Multiple Sclerosis. [PDF]

Int J Mol Sci
Ibrahim DR, Schwarz K, Kesharwani A, Tinschert R, Suiwal S, Schmitz F.   +5 more
europepmc   +1 more source

The potential role of S-nitrosoglutathione reductase in astrocyte BAFF expression and B cell activation in experimental autoimmune encephalomyelitis. [PDF]

J Neuroimmunol
Won J, Kim J, Islam SMT, Qiao F, Singh AK, Singh I.   +5 more
europepmc   +1 more source

Severe Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Leading to Assisted Suicide in a Patient in Her Late 30s: A Case Report. [PDF]

Cureus
Opala D, Villiger E, Levenfus I.
europepmc   +1 more source

Experimental Autoimmune Encephalomyelitis [PDF]

, 1995
Experimental Autoimmune Encephalomyelitis (EAE) is the prototype for cell-mediated autoimmune disease in general, and is the best animal model of human CNS inflammatory demyelinating disease. It has three forms, which vary in clinical course and neuropathology: acute EAE, hyperacute EAE and chronic relapsing EAE.
Pender, Michael P.
core   +4 more sources

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Experimental Autoimmune Encephalomyelitis in the Mouse

Current Protocols, 2021
AbstractThis article details the materials and methods required for both active induction and adoptive transfer of experimental autoimmune encephalomyelitis (EAE) in the SJL mouse strain using intact proteins or peptides from the two major myelin proteins: proteolipid protein (PLP) and myelin basic protein (MBP).
Collin, Laaker, Martin, Hsu, Zsuzsanna, Fabry, Stephen D, Miller, William J, Karpus   +4 more
openaire   +2 more sources

Microbiome Methods in Experimental Autoimmune Encephalomyelitis

Current Protocols, 2021
AbstractMicrobiome composition studies are increasingly shedding light on animal models of disease. This paper describes a protocol for analyzing the gut microbiome composition prior to and after the induction of mice to experimental autoimmune encephalomyelitis (EAE), the principal animal model of the human neuroinflammatory demyelinating disease ...
David P, Daberkow, Kristina, Hoffman, Hannah M, Kohl, Tyrel, Long, Trevor O, Kirby, Javier, Ochoa-Repáraz   +5 more
openaire   +2 more sources

Experimental Autoimmune Encephalomyelitis

2004
Experimental autoimmune encephalomyelitis (EAE) is an inflammatory demyelinating disease of the central nervous system that is induced in laboratory animals by the generation of an immune response against myelin epitopes. It has been used as a prototype of Th1- and/or Th17-driven, organ-specific autoimmunity and as a model for the human disease ...
Praveen, Rao, Benjamin M, Segal
openaire   +4 more sources

Experimental Autoimmune Encephalomyelitis

2021
Experimental autoimmune encephalomyelitis, originally experimental allergic encephalomyelitis, is the well-known animal model of multiple sclerosis, an immune- mediated, demyelinating, inflammatory chronic disease of the central nervous system. The experimental disease is widely utilized to test new therapies in preclinical studies, to investigate new ...
openaire   +3 more sources

Experimental Autoimmune Encephalomyelitis

Revue neurologique, 1998
Experimental autoimmune encephalomyelitis is an induced inflammatory and demyelinating disease of the central nervous system widely used as an animal model for multiple sclerosis. New insights into its pathophysiology have been possible due to recent immunological concepts.
A, Cornet, C, Vizler, R, Liblau
openaire   +3 more sources