Results 61 to 70 of about 49,920 (244)
Macrophage-targeted PEGylated liposomes ameliorate experimental autoimmune encephalomyelitis
Frontiers in ImmunologyMacrophages are the predominant immune cell type found in active multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE) lesions, where they contribute to demyelination and axonal damage. Depending on the lesion stage, these cells can
Alexander Muselman +10 more
doaj +1 more source
Behavioral investigation of mice with experimental autoimmune encephalomyelitis
Arquivos de Neuro-Psiquiatria, 2011 Multiple sclerosis is a neuroinflammatory disease that results in serious neurological disability. Besides physical impairment, behavioral symptoms are also common in patients with multiple sclerosis.
David Henrique Rodrigues +6 more
doaj +1 more source
Emodin attenuates inflammation and demyelination in experimental autoimmune encephalomyelitis
Neural Regeneration Research, 2023 Emodin, a substance extracted from herbs such as rhubarb, has a protective effect on the central nervous system. However, the potential therapeutic effect of emodin in the context of multiple sclerosis remains unknown.
Yue-Ran Cui +4 more
doaj +1 more source
Suppression of Experimental Autoimmune Encephalomyelitis by Ghrelin [PDF]
The Journal of Immunology, 2009 Abstract Ghrelin is a recently identified gastric hormone that displays strong growth hormone-releasing activity mediated by the growth hormone secretagogue receptor. While this unique endogenous peptide participates in the regulation of energy homeostasis, increases food intake, and decreases energy expenditure, its ability to ...
Michael-Mark, Theil +14 more
openaire +2 more sources
Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases
BMEMat, EarlyView.This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou +6 more
wiley +1 more source
Inosina previne a resposta inflamatória e nociceptiva induzida pelo modelo experimental de esclerose múltipla [PDF]
, 2015 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2015.A Esclerose Múltipla (EM) é uma doença autoimune mediada por linfócitos T e caracterizada por ...
Junqueira, Stella Célio
core
c-Jun N-Terminal Kinase as a Therapeutic Target in Experimental Autoimmune Encephalomyelitis. [PDF]
, 2020 c-Jun N-terminal kinase (JNK) is upregulated during multiple sclerosis relapses and at the peak of experimental autoimmune encephalomyelitis (EAE).
Bagnoud, Maud +17 more
core +1 more source
iNew Medicine, EarlyView.ABSTRACT This commentary integrates findings from three recent Cell reports to establish a unified mechanistic model of multiple sclerosis (MS) driven by the interplay between Epstein‐Barr virus (EBV) and the HLA‐DR15 genotype. EBV promotes CNS autoimmunity through three distinct but intersecting mechanisms.
Fang Zhu +2 more
wiley +1 more source
Understanding the Pathogenesis of Neuroinflammation using Magnetic Resonance Imaging [PDF]
, 2011 A non-invasive view of the brain with the aid of magnetic resonance imaging (MRI) is invaluable for studying pathological processes during autoimmune encephalomyelitis.
Waiczies, Sonia +3 more
core
, 2017 Huangqi glycoprotein (HQGP) is prepared from Astragalus membranaceus by ammonium sulfate precipitation. It was indicated that HQGP has an immunoregulatory effect.
Baoguo Xiao +9 more
core +1 more source