Results 61 to 70 of about 170,038,675 (262)

Evaluation of interactive web-based tools to stimulate reflection and communication about advance care planning with people with dementia and their family caregivers

BMC Palliative Care
Background People with dementia and their family caregivers often encounter challenges in engaging in advance care planning (ACP), such as a lack of information and difficulties in engaging in ACP conversations.
Fanny Monnet, Lara Pivodic, Charlèss Dupont, Tinne Smets, Aline De Vleminck, Chantal Van Audenhove, Lieve Van den Block   +6 more
doaj   +1 more source

The Support Needs of Patients Requesting Medical Aid in Dying and Their Relatives: A Qualitative Study Using Semi-Structured Interviews and Written Narratives

International Journal of Public Health
ObjectivesTo explore the support needs that patients and relatives experience throughout their medical aid in dying (MAID) trajectories.MethodsA qualitative study in Belgium in 2022 using 1) semi-structured interviews with and personal written narratives
Stijn Vissers, Stijn Vissers, Joni Gilissen, Joni Gilissen, Joachim Cohen, Joachim Cohen, Luc Deliens, Luc Deliens, Freddy Mortier, Freddy Mortier, Freddy Mortier, Kenneth Chambaere, Kenneth Chambaere, Sigrid Dierickx, Sigrid Dierickx   +14 more
doaj   +1 more source

Are the MORECare guidelines on reporting of attrition in palliative care research populations appropriate? A systematic review and meta-analysis of randomised controlled trials

BMC Palliative Care, 2020
Background Palliative care trials have higher rates of attrition. The MORECare guidance recommends applying classifications of attrition to report attrition to help interpret trial results.
Anna Oriani, Lesley Dunleavy, Paul Sharples, Guillermo Perez Algorta, Nancy J. Preston   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Adults' perspectives of experiences and preferences for end-of-life care

, 2023
Background: Decisions about end-of-life care often raise clinical and ethical challenges, especially when the person's capacity to contribute in the decision making at the end of life is limited.
Huang, Ya-Ling, Thorberg, Fred Arne, Wu, Chiung-Jung (Jo), Wang, Shou-Yu, Wu, Chiung-Jung Jo, Lin, Chun-Chih   +5 more
core   +1 more source

Implementing the theory-based advance care planning ACP+ programme for nursing homes: study protocol for a cluster randomised controlled trial and process evaluation

BMC Palliative Care, 2020
Background Research has highlighted the need for improving the implementation of advance care planning (ACP) in nursing homes. We developed a theory-based multicomponent ACP intervention (the ACP+ programme) aimed at supporting nursing home staff with ...
Joni Gilissen, Lara Pivodic, Annelien Wendrich-van Dael, Chris Gastmans, Robert Vander Stichele, Yvonne Engels, Myrra Vernooij-Dassen, Luc Deliens, Lieve Van den Block   +8 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Brief encounters: end of life decision-making in critical care [PDF]

, 2005
The health care system has, in many respects, been developed to oppose suffering. Yet health care’s almost compulsive urge to treat death as the enemy and to battle disease and injury with all available technology unavoidably results in suffering for ...
Sundin-Huard, Deborah
core  

Developing and validating a questionnaire for mortality follow-back studies on end-of-life care and decision-making in a resource-poor Caribbean country

BMC Palliative Care, 2020
Background Palliative and end-of-life care development is hindered by a lack of information about the circumstances surrounding dying in developing and resource-poor countries.
Nicholas Jennings, Kenneth Chambaere, Cheryl Cox Macpherson, Karen L. Cox, Luc Deliens, Joachim Cohen   +5 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source