Results 131 to 140 of about 7,379,857 (314)
The End is Never The End is Never The End
, 2022 A conclusion summarizing the contributions of the anthology on the theme of mental health in video games.
openaire +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
VOIP End-To-End Security using S/MIME and a Security Toolbox [PDF]
, 2014 Voice Over Internet Protocol (VOIP) is a rapidlygrowing Internet service for telephone communication. However, while it offers a number of cost advantages over traditional telephone service, it can pose a security threat, especially when used over public
Md. Shahidul Islm
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Development of end-to-end tests and extension of the continuous integration system of a web application [PDF]
reservedIl presente documento descrive il progetto di stage universitario svolto dal laureando Vanni Giachin nella primavera 2015, presso la sede di Vicenza dell'azienda Qlik, con l'obiettivo di sviluppare una serie di test end-to-end per il software ...
GIACHIN, VANNI
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Systems thinking in the prevention, control, and elimination of neglected tropical diseases (NTDs)
International Journal of Infectious DiseasesObjectives: It is estimated that more than one billion people are affected by neglected tropical diseases (NTDs). Whilst there are existing treatments to reduce morbidity, a major challenge is creating robust programs that are both country-led and ...
Louise K. Makau-Barasa +5 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source