Results 11 to 20 of about 99 (86)
Endocannabinoids and Reproduction [PDF]
Infertility is a worldwide reproductive health problem whose consequences have deep psychological and social impact in health, demographic change, and wellbeing. Thus, the knowledge of basic, conserved modulators of reproduction might contribute to the discovery of new potential target for the exploitation of drugs to treat infertility in humans ...
Rosaria Meccariello +3 more
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Background: Prurigo nodularis (PN) as an extremely pruritic and hyperplastic chronic dermatosis induces psychologically and physiologically stressful responses.
L. Chu +6 more
doaj +1 more source
Endocannabinoids and exercise [PDF]
Exercise induces changes in mental status, particularly analgesia, sedation, anxiolysis, and a sense of wellbeing. The mechanisms underlying these changes remain unknown. Recent findings show that exercise increases serum concentrations of endocannabinoids, suggesting a possible explanation for a number of these changes.
A, Dietrich, W F, McDaniel
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Estudio teórico de endocanabinoides análogos a anandamida
A partir de métodos computacionales, se estudió un total de 90 reacciones diseñadas por el grupo de investigación de farmoquímica de la UPTC cuya finalidad es la síntesis y determinación de posible actividad farmacológica de derivados de la anandamida en
Luis Carlos García Sánchez +2 more
doaj +1 more source
The Epigenetics of the Endocannabinoid System [PDF]
The endocannabinoid system (ES) is a cell-signalling system widely distributed in biological tissues that includes endogenous ligands, receptors, and biosynthetic and hydrolysing machineries. The impairment of the ES has been associated to several pathological conditions like behavioural, neurological, or metabolic disorders and infertility, suggesting
Meccariello Rosaria +6 more
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Receptores cannabinoides y vías de modulación del dolor.
Introducción: los endocannabinoides son mensajeros que contienen ácido araquidónico y que se almacenan en vesículas. Los más importantes son N-araquidoniletanolamina (anandamida) y 2-araquidonilglicerol (2-AG).
José Castro Barragán +2 more
doaj +1 more source
Endocannabinoid Turnover [PDF]
In this review, we consider the biosynthetic, hydrolytic, and oxidative metabolism of the endocannabinoids anandamide and 2-arachidonoylglycerol. We describe the enzymes associated with these events and their characterization. We identify the inhibitor profile for these enzymes and the status of therapeutic exploitation, which to date has been limited ...
Fowler, Christopher J. +2 more
openaire +4 more sources
Endocannabinoids and Immunity [PDF]
Over the last 10 years, a great boost of knowledge accumulated on the immunomodulatory and anti-inflammatory properties of endocannabinoids (eCBs). In this scenario, these bioactive lipids, which are produced by most immune cells along with a set of receptors and enzymes that regulate their synthesis and degradation, act as secondary modulators and ...
openaire +2 more sources
Endogenous cannabinoids play an important role in the physiology and behavioral expression of stress responses. Activation of the hypothalamic-pituitary-adrenal (HPA) axis, including the release of glucocorticoids, is the fundamental hormonal response to stress. Endocannabinoid (eCB) signaling serves to maintain HPA-axis homeostasis, by buffering basal
Riebe, C., Wotjak, C.
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Las plantas han sido un valioso recurso nutricional, terapéutico y medicinal a lo largo de la historia del hombre. La marihuana ha sido utilizada durante milenios para aliviar el dolor.
Marcela De Jesús Sánchez +2 more
doaj +1 more source

